In 2017,Xiong, Biquan; Hu, Chenghong; Gu, Jingfang; Yang, Changan; Zhang, Panliang; Liu, Yu; Tang, Kewen published 《Efficient and Controllable Esterification of P(O)-OH Compounds Using Uronium-Based Salts》.ChemistrySelect published the findings.COA of Formula: C12H22F6N6OP2 The information in the text is summarized as follows:
An efficient and convenient method is developed for the direct esterification of P(O)-OH compounds with alcs. under room temperature The protocol makes use of inexpensive uronium-based salts as coupling reagents and shows good tolerance towards numerous alcs., giving the corresponding esterification products in good to excellent yield. Phenols are also tolerated in this reaction. It is a simple way to produce a broad spectrum of functionalized phosphinates, phosphonates, and phosphates from basic P(O)-OH starting materials. Ph2P(O)OH.((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6COA of Formula: C12H22F6N6OP2) was used in this study.
((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It acts as a substitute for (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.COA of Formula: C12H22F6N6OP2
Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics