Tag: M.W=100-150

Smiglak, Marcin published the artcileAzolium azolates from reactions of neutral azoles with 1,3-dimethyl-imidazolium-2-carboxylate, 1,2,3-trimethyl-imidazolium hydrogen carbonate, and N,N-dimethyl-pyrrolidinium hydrogen carbonate, Synthetic Route of 14544-45-7, the publication is New Journal of Chemistry (2013), 37(5), 1461-1469, database is CAplus.

Utilizing previously reported synthetic protocols for the halide- and metal-free synthesis of organic salts, we have prepared a new group of imidazolium and pyrrolidinium azolate anion-based salts demonstrating the general applicability of the methodol. and expanding our investigation into non ion exchange routes to potentially energetic ionic liquids Eighteen salts, out of which six exhibit m.ps. below 100 °C, were prepared by a simple decarboxylation reaction, which resulted in clean formation of the new compounds without the need for extensive purification The low stability of the H₂CO₃ byproduct, and its decomposition to CO₂ and H₂O in aqueous media, allows for purification of the salts by evaporation only.

New Journal of Chemistry published new progress about 14544-45-7. 14544-45-7 belongs to triazoles, auxiliary class Triazoles, name is 5-Nitro-1H-1,2,3-triazole, and the molecular formula is C20H17FO4S, Synthetic Route of 14544-45-7.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Dunn, G. L. published the artcileOrally active 7-phenylglycyl cephalosporins. Structure-activity studies related to cefatrizine (SK & F 60771), Application of Sodium 1,2,3-triazole-5-thiolate, the publication is Journal of Antibiotics (1976), 29(1), 65-80, database is CAplus and MEDLINE.

A series of 24 broad-spectrum 7-phenylglycyl cephalosporins with 3-heterocyclicthiomethyl substituents was prepared by displacing the 3-acetoxy group of 7-aminocephalosporanic acid [957-68-6] with an appropriate heterocyclic thiol, followed by acylation by the mixed anhydride method. The effects of benzene ring hydroxylation and 3-substituent variation on in vitro antibacterial activity, height and duration of mouse serum levels, and protection against bacterial infection in the mouse were examined The most active, cefatrizine (I) [51627-14-6], had in vitro and in vivo activities and serum levels significantly higher than obtained with cephalexin [15686-71-2] or cephaloglycin [3577-01-3].

Journal of Antibiotics published new progress about 59032-27-8. 59032-27-8 belongs to triazoles, auxiliary class Triazoles, name is Sodium 1,2,3-triazole-5-thiolate, and the molecular formula is C2H2N3NaS, Application of Sodium 1,2,3-triazole-5-thiolate.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Ferris, James P. published the artcileRibopyranosyldiaminomaleonitrile: a key intermediate for the synthesis of nucleosides, Quality Control of 53817-16-6, the publication is Journal of the Chemical Society, Chemical Communications (1978), 1094-6, database is CAplus.

H₂NC(CN):C(NH₂)CN with D-ribose in MeOH containing AcOH (18h, 25°) gave 51% of the title compound I. Sequential treatment of I with Ac₂O (pyridine, 2 h, 0-5°, yield 49%) and isopentyl nitrite (MeOH, 20 min, room temperature) gave 37% β- and 20% α-II. Two related imidazole ribosides were also prepared from I.

Journal of the Chemical Society, Chemical Communications published new progress about 53817-16-6. 53817-16-6 belongs to triazoles, auxiliary class Triazoles, name is 1H-1,2,3-Triazole-4,5-dicarbonitrile, and the molecular formula is C4HN5, Quality Control of 53817-16-6.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Lai, Qi published the artcile1,2,3-Triazole with linear and branched catenated nitrogen chains – The role of regiochemistry in energetic materials, HPLC of Formula: 84406-63-3, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2021), 128148, database is CAplus.

Two energetic mols. possessing a linear and branched N8 structure were synthesized based on the oxidative coupling of N-aminotriazoles. Despite the same chem. formula and azo functionality, the decomposition temperatures (T_d) of these two regioisomers reflect a gap of more than 80°C. Based on the data of single crystal X-ray diffraction, comparative investigation associated with the bond length and stacking pattern rationalize the different properties of d. and mol. stability. Theor. analyses, e.g., charge distribution and Hirshfeld surface, were carried out subsequently to gain more insight into the regiochem. of catenated nitrogen-atom chains. The difference of charge distribution between two mols. caused by regional heterogeneity is the main reason for their different stabilities.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 84406-63-3. 84406-63-3 belongs to triazoles, auxiliary class Triazole,Nitro Compound, name is 4-Nitro-2H-1,2,3-triazole, and the molecular formula is C2H2N4O2, HPLC of Formula: 84406-63-3.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Voitekhovich, Sergei V. published the artcileSelective complexation of 1-ethyl-5-nitro-1,2,3-triazole (entz) with copper(II) salts: Preparation and characterization of [Cu(entz)₂Cl₂] and [Cu(entz)₄(H₂O)₂](ClO₄)₂, Name: 5-Nitro-1H-1,2,3-triazole, the publication is Inorganic Chemistry Communications (2012), 77-80, database is CAplus.

Treatment of a mixture of isomeric N-ethyl-4(5)-nitro-1,2,3-triazoles with copper(II) chloride or copper(II) perchlorate was found to yield crystalline complexes with 1-ethyl-5-nitro-1,2,3-triazole (entz), namely [Cu(entz)₂Cl₂] or [Cu(entz)₄(H₂O)₂](ClO₄)₂, resp. The obtained complexes, being the rare examples of coordination compounds of vicinal nitrotriazoles, have been characterized by X-ray diffraction and thermal methods. Both compounds present mononuclear complexes with entz coordinating through N3 atom of heterocycle. The complexes are readily decomposed under action of aqueous ammonia generating pure 1-ethyl-5-nitro-1,2,3-triazole with high yield. Succession of complexation and decomplexation reactions was shown to be a simple procedure for isolation of 1-ethyl-5-nitro-1,2,3-triazole from isomeric mixtures formed under alkylation of 4-nitro-1,2,3-triazole.

Inorganic Chemistry Communications published new progress about 14544-45-7. 14544-45-7 belongs to triazoles, auxiliary class Triazoles, name is 5-Nitro-1H-1,2,3-triazole, and the molecular formula is C11H10O, Name: 5-Nitro-1H-1,2,3-triazole.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Sukhanov, Gennady T. published the artcileAcidic N-dealkylation in nitrotriazolium salts, SDS of cas: 14544-45-7, the publication is Mendeleev Communications (2022), 32(2), 215-217, database is CAplus.

New selective synthesis of 1-alkyl-4-nitro-1,2,3-triazoles I [R¹ = Me, Et, Bn, etc.] and 1-alkyl-5-nitro-1,2,3-triazoles II [R² = Me, Et, n-Bu, etc.] had been developed, involving acid N-dealkylation of 1,3-dialkyl-4-nitro-1,2,3-triazolium salts III. The assortment of novel 1-alkyl-4(5)-nitro-1,2,3-triazoles had been thus essentially expanded. Treatment of relative 3-nitro-1,2,4-triazolium salts IV [R³ = H, Me; R⁴ = Me, Et, t-Bu; R⁵ = Me, Et] with HCl or HBr proceeded mostly as S^ipso_N-substitution of the nitro group.

Mendeleev Communications published new progress about 14544-45-7. 14544-45-7 belongs to triazoles, auxiliary class Triazoles, name is 5-Nitro-1H-1,2,3-triazole, and the molecular formula is C44H28ClFeN4, SDS of cas: 14544-45-7.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Sukhanov, Gennady T. published the artcileSynthesis of 1-(Adamantan-1-yl)-1H-1,2,3-Triazoles and their Salts by Adamantylation in AdOH-HClO₄ and AdOH-H₂SO₄ Systems, COA of Formula: C2H2N4O2, the publication is Chemistry of Heterocyclic Compounds (New York, NY, United States) (2019), 55(12), 1197-1203, database is CAplus.

1-(Adamantan-1-yl)-1H-1,2,3-triazoles and a series of 1-(adamantan-1-yl)-3-alkyl-1,2,3-triazolium salts were synthesized by regioselective adamantylation of 1,2,3-triazole derivatives The direction of the attack by the adamantyl cation at the N-1 nitrogen atom and the regioselectivity of the processes of adamantylation and quaternization were ensured by a number of factors: the specificity of the properties of the high-acid systems AdOH-HClO₄ and AdOH-H₂SO₄, as well as the structural aspect and high reactivity of adamantan-1-ol.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about 14544-45-7. 14544-45-7 belongs to triazoles, auxiliary class Triazoles, name is 5-Nitro-1H-1,2,3-triazole, and the molecular formula is C10H16O2, COA of Formula: C2H2N4O2.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Abboud, Jose-Luis M. published the artcileBasicity of N-H- and N-methyl-1,2,3-triazoles in the gas phase, in solution, and in the solid state – an experimental and theoretical study, Recommanded Product: 5-Nitro-1H-1,2,3-triazole, the publication is European Journal of Organic Chemistry (2001), 3013-3024, database is CAplus.

The gas-phase and aqueous basicities of six 1,2,3-triazoles have been determined, the former by FT-ICR and the latter by spectrophotometry and ¹H NMR. The gas-phase experiments agree very well with the Gibbs free energies calculated at the B3LYP/6-31G^* level. In contrast, only semiquant. ascertainments are possible when basicities in the gas phase and in solution are compared. It is possible, with the aid of calculations, to obtain a complete picture of the complex equilibrium involved in C-substituted N-H-1,2,3-triazoles. The crystal structures of 4(5)-phenyl-1,2,3-triazole (4) and 4(5)-nitro-1,2,3-triazole (15) have been determined In the gas phase, 2H tautomers b always predominate, while in aqueous solution, both 1H and 2H tautomers – a and b – are present. Finally, in the solid state, 1,2,3-triazole 1 exists as a 1:1 tautomer mixture , while 4 and 15 exist as single tautomeric structures.

European Journal of Organic Chemistry published new progress about 14544-45-7. 14544-45-7 belongs to triazoles, auxiliary class Triazoles, name is 5-Nitro-1H-1,2,3-triazole, and the molecular formula is C2H2N4O2, Recommanded Product: 5-Nitro-1H-1,2,3-triazole.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Abboud, Jose-Luis M. published the artcileBasicity of N-H- and N-methyl-1,2,3-triazoles in the gas phase, in solution, and in the solid state – an experimental and theoretical study, Safety of 4-Nitro-2H-1,2,3-triazole, the publication is European Journal of Organic Chemistry (2001), 3013-3024, database is CAplus.

The gas-phase and aqueous basicities of six 1,2,3-triazoles have been determined, the former by FT-ICR and the latter by spectrophotometry and ¹H NMR. The gas-phase experiments agree very well with the Gibbs free energies calculated at the B3LYP/6-31G^* level. In contrast, only semiquant. ascertainments are possible when basicities in the gas phase and in solution are compared. It is possible, with the aid of calculations, to obtain a complete picture of the complex equilibrium involved in C-substituted N-H-1,2,3-triazoles. The crystal structures of 4(5)-phenyl-1,2,3-triazole (4) and 4(5)-nitro-1,2,3-triazole (15) have been determined In the gas phase, 2H tautomers b always predominate, while in aqueous solution, both 1H and 2H tautomers – a and b – are present. Finally, in the solid state, 1,2,3-triazole 1 exists as a 1:1 tautomer mixture , while 4 and 15 exist as single tautomeric structures.

European Journal of Organic Chemistry published new progress about 84406-63-3. 84406-63-3 belongs to triazoles, auxiliary class Triazole,Nitro Compound, name is 4-Nitro-2H-1,2,3-triazole, and the molecular formula is C2H2N4O2, Safety of 4-Nitro-2H-1,2,3-triazole.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Al-Azmi, Amal published the artcileNovel 2H-1,2,3-triazole sodium complex from N-[2-amino-1,2-dicyanovinyl]alkanamides, Category: triazoles, the publication is Heterocycles (2007), 71(10), 2183-2201, database is CAplus.

Diazotization at 0 °C of N-[2-amino-1,2-dicyanovinyl]ethanamide or the propanamide analog prepared from diaminomaleonitrile (DAMN) I using aqueous acetic acid and NaNO₂ solution furnished sodium complex II. The x-ray structure of the complex II showed that it is a 1:1 mixture of the neutral 2H-triazole heterocycle III and its anion deprotonated at the central (N) atom of the ring, together with a sodium counterion and two coordinated water mols. However, when the diazotization reaction was carried out in the presence of aqueous HCl, the product was 5-cyano-2H-[1,2,3]triazole-4-carboxylic acid amide monohydrate III. Diazotization of I using aqueous HCl furnished 1H-1,2,3-triazole-4,5-dicarbonitrile IV, whereas with acetic acid there was no reaction, and hence no route analogous to that leading to complex II. The structure of both complex II and the triazole monohydrate III were solved using x-ray crystallog., and the compounds under study were fully characterized using spectroscopic techniques.

Heterocycles published new progress about 53817-16-6. 53817-16-6 belongs to triazoles, auxiliary class Triazoles, name is 1H-1,2,3-Triazole-4,5-dicarbonitrile, and the molecular formula is C4HN5, Category: triazoles.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics