Tag: M.W=0-100

Wiench, P; Gonzalez, Z; Gryglewicz, S; Menendez, R; Gryglewicz, G in [Wiench, Piotr; Gryglewicz, Stanislaw; Gryglewicz, Grazyna] Wroclaw Univ Sci & Technol, Fac Chem, Dept Polymer & Carbonaceous Mat, Gdanska 7-9, PL-50344 Wroclaw, Poland; [Gonzalez, Zoraida; Menendez, Rosa] CSIC, Inst Nacl Carbon INCAR, Francisco Pintado Fe 26, Oviedo 33011, Spain published Enhanced performance of pyrrolic N-doped reduced graphene oxide-modified glassy carbon electrodes for dopamine sensing in 2019.0, Cited 60.0. Safety of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Two different nitrogen-doped reduced graphene oxides (N-rGOs) were used to modify glassy carbon electrodes (GCE/N-rGOs) as electrochemical sensors for the detection of dopamine (DA). For comparison, GCE/rGO was also studied. The N-rGOs were synthesized via hydrothermal treatment of graphene oxide (GO) with the N-dopants amitrole and urea. The resultant graphene materials exhibited distinct types and distributions of nitrogenated functional groups, but they possessed a similar oxygen content, thus avoiding interference from oxygenated groups. Pyridinic nitrogen was introduced into the rGO structure when amitrole was used as the N-dopant, whereas pyrrolic nitrogen was preferentially formed in the reaction with urea. After optimization of several experimental parameters and sensor calibration, the GCE/pyrrolic-N-rGO electrode was found to exhibit superior electrochemical performance compared with the pyridinic-N-rGO one, demonstrating a limit of detection and sensitivity of 335 nM and 3.51 mu A mu M-1, respectively. This sensor also showed better selectivity in the presence of interfering agents in the forms of ascorbic and uric acids. A significant improvement of sensor parameters can be explained in terms of the contribution of electrons derived from the pyrrolic structure to the delocalized C sp(2)-conjugated graphene system.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Yu, L; Xiong, SS; Lin, YH; Li, LY; Peng, JJ; Liu, W; Huang, XX; Wang, H; Li, J in [Yu, Liang; Lin, Yuhan; Liu, Wei; Huang, Xiaoxi; Wang, Hao; Li, Jing] Shenzhen Polytech, Hoffmann Inst Adv Mat, Shenzhen 518055, Guangdong, Peoples R China; [Xiong, Shunshun] China Acad Engn Phys, Inst Nucl Phys & Chem, Mianyang 621900, Sichuan, Peoples R China; [Li, Liangying; Li, Jing] Rutgers State Univ, Dept Chem & Chem Biol, 123 Bevier Rd, Piscataway, NJ 08854 USA; [Li, Liangying] Zhejiang Univ, Coll Chem & Biol Engn, Minist Educ, Key Lab Biomass Chem Engn, Hangzhou 310027, Zhejiang, Peoples R China; [Peng, Junjie] South China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510641, Guangdong, Peoples R China published Tuning the Channel Size and Structure Flexibility of Metal-Organic Frameworks for the Selective Adsorption of Noble Gases in 2019.0, Cited 19.0. Category: Triazoles. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Two ultramicroporous metal-organic frameworks, Zn(ox)(0.5)(trz) and Zn(ox)(0.5)(atrz) (ox = oxalate, trz = triazolate, and atrz = 3-aminotriazolate), have been synthesized and tested for the adsorptive separation of Xe and Kr. We demonstrate that the Xe/Kr adsorption selectivity relates to the pore size as well as the structure flexibility of the adsorbents.

Welcome to talk about 61-82-5, If you have any questions, you can contact Yu, L; Xiong, SS; Lin, YH; Li, LY; Peng, JJ; Liu, W; Huang, XX; Wang, H; Li, J or send Email.. Category: Triazoles

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Design, synthesis, characterization, and physical property determination of a new ionic liquid: the preparation of triazolo-pyrimidines at room temperature under metal-free conditions WOS:000557222500001 published article about AGENTS; ACID in [Shahnavaz, Zohreh; Khaligh, Nader Ghaffari; Johan, Mohd Rafie] Univ Malaya, Nanotechnol & Catalysis Res Ctr, Inst Postgrad Studies, Kuala Lumpur 50603, Malaysia; [Mihankhah, Taraneh] Iran Univ Sci & Technol, Sch Civil Engn, Dept Water & Environm Engn, Environm Res Lab, Tehran 16765163, Iran in 2020.0, Cited 19.0. Computed Properties of C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A new ionic liquid is synthesized, and its chemical structure is characterized by FTIR, 1D NMR and 2D NMR, and mass analyses. The thermal behavior and thermal stability of this ionic liquid are investigated. The results approved the formation of 4,4MODIFIER LETTER PRIME-trimethylene-N,NMODIFIER LETTER PRIME-dipiperidinium sulfate instead of 4,4MODIFIER LETTER PRIME-trimethylene-N,NMODIFIER LETTER PRIME-dipiperidinium hydrogen sulfate. Moreover, the synthesis of triazolo-pyrimidine derivatives was successfully conducted in the presence of new ionic liquid at room temperature under metal-free conditions, which demonstrated the catalytic efficiency of this ionic liquid. The workup was carried out without the utilization of high-cost column chromatography. After extraction of desired products, the residual ionic liquid could be recycled and reused in the next runs. New ionic liquid exhibited high catalytic activity even after fifth run with no significant change in the chemical structure.

Welcome to talk about 61-82-5, If you have any questions, you can contact Shahnavaz, Z; Khaligh, NG; Mihankhah, T; Johan, MR or send Email.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019.0 POLYM POLYM COMPOS published article about MECHANICAL-PROPERTIES; COMPOSITE RESIN; THERMAL-DEGRADATION; FILLER MORPHOLOGY; FLEXURAL STRENGTH; WEAR; PARTICLES; MEMBRANES; FRACTION; BEHAVIOR in [Yushau, Umar S.] D Yammadawa 628, Gwale Lga, Kano State, Nigeria; [Almofeez, Lama; Bozkurt, Ayhan] Imam Abdulrahman Bin Faisal Univ, Dept Biophys, IRMC, Dammam 31441, Saudi Arabia in 2019.0, Cited 40.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Product Details of 61-82-5

This article is focused on the preparation and characterization of functional nanosilica incorporated dental resins with better mechanical, cytotoxicity, sorption, and solubility properties. Silica nanoparticles were synthesized via Stober method and were functionalized with 3-amino-1,2,4-triazole. Dental nanocomposites were produced by embedding the functionalized nanosilica into bisphenol-A-glycidyl methacrylate/triethylene glycol dimethacrylate matrix to form B1-B6 series. This was achieved by mechanical mixing of the monomer (50:50 wt%), filler (10-60 wt%), initiator combination (CQ/EDMAB:O. 1 :0.4 wt%) and then followed by LED light curing (wavelength: 450-500 nm, power density:1000 mW cm(-2)) for 60 s. Fourier transform infrared spectroscopy, scanning electron microscopy, and thermogravimetric analysis techniques were used for characterization of the materials. Cytotoxicity tests were performed to evaluate cell viability and mechanical tests were done to check mechanical strength and stability of the materials. The mean sorption and solubility values of the materials were measured by making a series of experiments on different composite formulations.

Welcome to talk about 61-82-5, If you have any questions, you can contact Yushau, US; Almofeez, L; Bozkurt, A or send Email.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Product Details of 61-82-5. In 2021.0 ENVIRON MOL MUTAGEN published article about NONGENOTOXIC CHEMICALS; RECOMMENDED LISTS; OXIDATIVE STRESS; FOLLOW-UP; ASSAY; PERFORMANCE; MUTAGENESIS; QUERCETIN; THRESHOLD; TESTS in [Allemang, Ashley; De Abrew, K. Nadira; Shan, Yuqing K.; Pfuhler, Stefan] Procter & Gamble Co, Global Prod Stewardship, Cincinnati, OH USA; [Krailler, Jesse M.] Procter & Gamble Co, Data & Modeling Sci, Cincinnati, OH USA in 2021.0, Cited 35.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

A key step in the risk assessment process of a substance is the assessment of its genotoxic potential. Irrespective of the industry involved, current approaches rely on combinations of two or three in vitro tests and while highly sensitive, their specificity is thought to be limited. A refined in vitro genotoxicity testing strategy with improved predictive capacity would be beneficial and 3R friendly as it helps to avoid unnecessary in vivo follow-up testing. Here, we describe a proof of concept study evaluating a balanced set of compounds that have in vivo negative or positive outcomes, but variable in vitro data, to determine if we could differentiate between direct and indirect acting genotoxicants. Compounds were examined in TK6 cells using an approach in which the same sample was used to evaluate both early genomic markers (Affymetrix analysis 4 hr post treatment), and the genotoxic outcome (micronuclei [MN] after 24 hr). The resulting genomic data was then analyzed using the TGx-DDI biomarker, Connectivity mapping and whole genome clustering. Chemicals were also tested in the ToxTracker assay, which uses six different biomarker genes. None of the methods correctly differentiated all direct from indirect acting genotoxicants when used alone, however, the ToxTracker assay, TGx-DDI biomarker and whole genome approaches provided high predictive capacity when used in combination with the MN assay (1/18, 2/18, 1/18 missed calls). Ultimately, a fit for purpose combination will depend on the specific tools available to the end user, as well as considerations of the unique benefits of the individual assays.

Welcome to talk about 61-82-5, If you have any questions, you can contact Allemang, A; De Abrew, KN; Shan, YQK; Krailler, JM; Pfuhler, S or send Email.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Quality Control of 1H-1,2,4-Triazol-5-amine. Suarez-Diez, M; Porras, S; Laguna-Teno, F; Schaap, PJ; Tamayo-Ramos, JA in [Suarez-Diez, Maria; Schaap, Peter J.] Wageningen Univ & Res, Lab Syst & Synthet Biol, Stippeneg 4, NL-6708 WE Wageningen, Netherlands; [Porras, Santiago] Univ Burgos, Dept Econ Aplicada, Plaza Infanta Dona Elena S-N, Burgos 09001, Spain; [Laguna-Teno, Felix; Tamayo-Ramos, Juan A.] Univ Burgos, Int Res Ctr Crit Raw Mat ICCRAM, Plaza Misael Banuelos S-N, Burgos 09001, Spain published Toxicological response of the model fungus Saccharomyces cerevisiae to different concentrations of commercial graphene nanoplatelets in 2020.0, Cited 92.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Graphene nanomaterials have attracted a great interest during the last years for different applications, but their possible impact on different biological systems remains unclear. Here, an assessment to understand the toxicity of commercial polycarboxylate functionalized graphene nanoplatelets (GN) on the unicellular fungal model Saccharomyces cerevisiae was performed. While cell proliferation was not negatively affected even in the presence of 800 mg L-1 of the nanomaterial for 24 hours, oxidative stress was induced at a lower concentration (160 mg L-1), after short exposure periods (2 and 4 hours). No DNA damage was observed under a comet assay analysis under the studied conditions. In addition, to pinpoint the molecular mechanisms behind the early oxidative damage induced by GN and to identify possible toxicity pathways, the transcriptome of S. cerevisiae exposed to 160 and 800 mg L-1 of GN was studied. Both GN concentrations induced expression changes in a common group of genes (337), many of them related to the fungal response to reduce the nanoparticles toxicity and to maintain cell homeostasis. Also, a high number of genes were only differentially expressed in the GN800 condition (3254), indicating that high GN concentrations can induce severe changes in the physiological state of the yeast.

Quality Control of 1H-1,2,4-Triazol-5-amine. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Name: 1H-1,2,4-Triazol-5-amine. van Onselen, R; Downing, TG in [van Onselen, Rianita; Downing, Tim G.] Nelson Mandela Univ, Dept Biochem & Microbiol, POB 77000, ZA-6031 Port Elizabeth, South Africa published beta-N-methylamino-L-alanine Inhibits Human Catalase Activity: Possible Implications for Neurodegenerative Disease Development in 2019.0, Cited 62.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

The naturally produced, nonprotein amino acid beta-N-methylamino-l-alanine (BMAA) has been proposed as a significant contributor to sporadic neurodegenerative disease development worldwide. However, the existing hypothesized mechanisms of toxicity do not adequately explain the role of BMAA in neurodegenerative disease development. There is evidence for BMAA-induced enzyme inhibition, but the effect of BMAA on human stress response enzymes has received little attention, despite the well-described role of oxidative stress in neurodegenerative disease development. The aim of this study was therefore to investigate the effect of BMAA on human catalase activity and compare it to the known inhibitor 3-amino-1,2,4-triazole. BMAA inhibited human erythrocyte catalase in a cell-free exposure to the same extent as the known inhibitor. Based on enzyme kinetics, the inhibition appears to be noncompetitive, possibly as a result of BMAA binding in the nicotinamide adenine dinucleotide phosphate (NADPH) binding site. BMAA-induced catalase inhibition was also observed in a human cell line culture. We therefore propose that BMAA-induced enzyme inhibition, specifically catalase inhibition, is a mechanism of toxicity that may contribute to the neurotoxicity of BMAA, further supporting the role of BMAA in neurodegenerative disease development.

Welcome to talk about 61-82-5, If you have any questions, you can contact van Onselen, R; Downing, TG or send Email.. Name: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Transition-metal-free N-arylation: A general approach to aza-fused poly-heteroaromatics WOS:000486513400001 published article about ONE-POT SYNTHESIS; EFFICIENT METHOD; INTRAMOLECULAR CYCLIZATION; OXIDATIVE AMINATION; C(SP(3))-H BONDS; DERIVATIVES; COPPER; PALLADIUM; BENZODIAZEPINE; INDOLES in [Annareddygari, Srikanth; Kasireddy, Venkateshwer Reddy] Jawaharlal Nehru Technol Univ, Dept Chem, Coll Engn, Hyderabad 500085, India; [Annareddygari, Srikanth; Reddy, Jayachandra] Dr JCR BIOSCEIENCES PRIVATE Ltd, Dept Res & Dev, Plot 79-80,Cherlapalli Phase 3 Ind Pk, Hyderabad 500039, India; [Kasireddy, Venkateshwer Reddy] Jawaharlal Nehru Technol Univ, Dept Chem, CMR Engn Coll, Hyderabad 501401, India in 2019.0, Cited 55.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Safety of 1H-1,2,4-Triazol-5-amine

A new and efficient method for the synthesis of various aza-fused poly-hetero aromatics has been described. This protocol includes an intermolecular condensation followed by metal-free base-promoted intramolecular C?N coupling reaction. The advantage of this one-pot transformation lies in the use of simple cyclic amidines-like compounds without prefunctionalization of the starting heterocycles.

Safety of 1H-1,2,4-Triazol-5-amine. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 61-82-5. Authors Zhou, SR; Dong, Z; Yang, R; Wang, XY; Ye, ZW in WILEY-V C H VERLAG GMBH published article about in [Zhou, Shengren; Dong, Zhen; Yang, Rui; Wang, Xieyang; Ye, Zhiwen] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China in 2021.0, Cited 24.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Two energetic compounds, erythritol tetranitrocarbamate (ETNC) and pentaerythritol tetranitrocarbamate (PETNC), and their salts, were synthesized in three steps, characterized and compared. All synthesized compounds were characterized by IR, DSC and multinuclear NMR spectroscopy. Four compounds were further investigated by single crystal X-ray diffraction. All nonmetal salts show extremely low mechanical sensitivity (IS >= 30 J; FS >= 360 N). The heats of formation were calculated using Gaussian 09, and the detonation performances were calculated using EXPLO 5. Although these nonmetal salts are lower than the neutral compounds ETNC (D: 7960 m s(-1), P: 27.4 GPa) and PETNC (D: 7629 m s(-1), P: 24.3 GPa), they possess high detonation performances that are better than TNT. Erythritol-based and corresponding pentaerythritol-based energetic materials were compared in terms of their thermostability, detonation velocity and detonation pressure. They were also compared in their respective series. ETNC and PETNC and their salts have short preparation steps and are easy to isolate in high yields, and thus have promising potential applications as explosives.

Welcome to talk about 61-82-5, If you have any questions, you can contact Zhou, SR; Dong, Z; Yang, R; Wang, XY; Ye, ZW or send Email.. Recommanded Product: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 61-82-5. Authors Fandzloch, M; Jedrzejewski, T; Dobrzanska, L; Esteban-Parra, GM; Wisniewska, J; Paneth, A; Paneth, P; Sitkowski, J in ROYAL SOC CHEMISTRY published article about in [Fandzloch, Marzena] Polish Acad Sci, Inst Low Temp & Struct Res, Okolna 2, PL-50422 Wroclaw, Poland; [Jedrzejewski, Tomasz] Nicolaus Copernicus Univ Torun, Fac Biol & Vet Sci, Dept Immunol, Lwowska 1, PL-87100 Torun, Poland; [Dobrzanska, Liliana; Wisniewska, Joanna] Nicolaus Copernicus Univ Torun, Fac Chem, Gagarina 7, PL-87100 Torun, Poland; [Esteban-Parra, Gines M.] Univ Granada, Dept Inorgan Chem, Avda Severo Ochoa S-N, Granada 18071, Spain; [Paneth, Agata] Med Univ Lublin, Fac Pharm, Dept Organ Chem, Chodzki 4a, PL-20093 Lublin, Poland; [Paneth, Piotr] Lodz Univ Technol, Fac Chem, Inst Appl Radiat Chem, Zeromskiego 116, PL-90924 Lodz, Poland; [Sitkowski, Jerzy] Natl Inst Med, Chelmska 30-34, PL-00725 Warsaw, Poland; [Sitkowski, Jerzy] Polish Acad Sci, Inst Organ Chem, Kasprzaka 44-52, PL-01224 Warsaw, Poland in 2021.0, Cited 91.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Three half-sandwich organometallic ruthenium(II) complexes containing purine analogs such as triazolo-pyrimidines of general formula [(eta(6)-p-cym)Ru(L)Cl-2], where p-cym represents p-cymene and L is 5,6,7-trimethyl-1,2,4-triazolo[1,5-alpyrimidine (tmtp for 1), 5,7-diethyl-1,2,4-triazolo[1,5-a]pyrimidine (detp for 2) and 5-methyl-1,2,4-triazolo(1,5-a]pyrimidin-7(4H)-one (HmtpO for 3), have been synthesized and characterized by elemental analysis, infrared, multinuclear magnetic resonance spectroscopic techniques (H-1, C-13, N-15), and single-crystal X-ray diffraction (for 1 and 2). All these complexes have been thoroughly screened for their in vitro cytotoxicity against MCF-7 and HeLa cell lines as well as L929 murine fibroblast cells, indicating [(eta(6)-p-cym)Ru(HmtpO)Cl-2] (3) as the most active representative against the HeLa cell line and simultaneously being 64-fold less toxic to normal L929 murine fibroblast cells than cisplatin. At the same time, 3 has shown antimetastatic activity comparable to NAMI-A against HeLa cells both after 24 and 48 h of treatment in a wound healing assay. in order to better understand the mechanism of anti-cancer action and differences in the cytotoxic activity of 1-3, the studies were expanded to determining their lipophilicity, the kinetic stability at pH 6.5-8, the effect on reactive oxygen species (ROS) production in HeLa cells and interactions with significant biomolecules (DNA and albumin) by using molecular docking and circular dichroism (CD) experiments. Furthermore, antiparasitic studies against L braziliensis, L. infantum and T cruzi reveal that the newly synthesized complexes 1-3 are very promising candidates which can compete with commercial antiparasitic drugs. Complex 3 in particular, on top of exhibiting high antiparasitic effect (IC50 < 1 mu M against two strains), reaches a selectivity index >1000.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics