Tag: M.W=0-100

SDS of cas: 61-82-5. I found the field of Polymer Science very interesting. Saw the article Organotin Polymers as Antiviral Agents Including Inhibition of Zika and Vaccinia Viruses published in 2020.0, Reprint Addresses Roner, MR (corresponding author), Univ Texas Arlington, Dept Biol, Arlington, TX 76010 USA.; Carraher, CE (corresponding author), Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

The ability to inhibit two important viruses is described. Two groups of polymers exhibited ability to totally inhibit the Zika virus. These polymers are derived from organotin dihalides and camphoric acid and lamivudine. This is the initial report of complete inhibition of the Zika virus by simple drugs. The ability to inhibit vaccinia virus is also reported. The inhibition of the vaccinia virus is shown by a number of organotin drugs including those also derived from lamivudine and camphoric acid and additional drugs derived from 3-amino-1,2,4-triazole, dicumarol, 4,6-diaminopyridine, alpha-cyano-4-hydroxcinnamic acid, and a variety of organotin polyethers including water soluble polymers derived from poly(ethylene glycol). All the drugs described in these studies are rapidly (< 30 s) synthesized using commercially available reactants at room temperature employing the interfacial reaction system that is employed industrially so that scale up to kilograms is relatively straight forward. SDS of cas: 61-82-5. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Safety of 1H-1,2,4-Triazol-5-amine. Authors Mu, YZ; Maharjan, Y; Dutta, RK; Wei, XF; Kim, JH; Son, J; Park, C; Park, R in PUBLIC LIBRARY SCIENCE published article about in [Mu, Yizhu; Maharjan, Yunash; Dutta, Raghbendra Kumar; Wei, Xiaofan; Kim, Jin Hwi; Son, Jinbae; Park, Channy; Park, Raekil] Gwangju Inst Sci & Technol, Dept Biomed Sci & Engn, Gwangju, South Korea in 2021.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Peroxisomes are metabolically active organelles which are known to exert anti-inflammatory effects especially associated with the synthesis of mediators of inflammation resolution. However, the role of catalase and effects of peroxisome derived reactive oxygen species (ROS) caused by lipid peroxidation through 4-hydroxy-2-nonenal (4-HNE) on lipopolysaccharide (LPS) mediated inflammatory pathway are largely unknown. Here, we show that inhibition of catalase by 3-aminotriazole (3-AT) results in the generation of peroxisomal ROS, which contribute to leaky peroxisomes in RAW264.7 cells. Leaky peroxisomes cause the release of matrix proteins to the cytosol, which are degraded by ubiquitin proteasome system. Furthermore, 3-AT promotes the formation of 4HNE-I kappa B alpha adduct which directly interferes with LPS induced NF-kappa B activation. Even though, a selective degradation of peroxisome matrix proteins and formation of 4HNE- I kappa B alpha adduct are not directly related with each other, both of them are could be the consequences of lipid peroxidation occurring at the peroxisome membrane.

Welcome to talk about 61-82-5, If you have any questions, you can contact Mu, YZ; Maharjan, Y; Dutta, RK; Wei, XF; Kim, JH; Son, J; Park, C; Park, R or send Email.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Category: Triazoles. In 2019.0 J MOL STRUCT published article about METAL-ORGANIC FRAMEWORKS; IONIC LIQUID; INHIBITORS; DESIGN; DERIVATIVES; EFFICIENT; POTENT; WATER; ACID in [Abdollahi-Basir, Mohammad Hossein; Shirini, Farhad; Tajik, Hassan] Univ Guilan, Coll Sci, Dept Chem, Rasht 4133519141, Iran; [Ghasemzadeh, Mohammad Ali] Islamic Azad Univ, Qom Branch, Dept Chem, Qom, Iran in 2019.0, Cited 31.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Zinc terephthalate metal-organic framework catalyzed one-pot, three-component reaction of 3-amino-1H-1,2,4-triazoles, aromatic aldehydes and barbituric acid to prepare some new pyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidinediones. The reactions conducted under ultrasonic irradiation and solvent-free conditions with good to excellent yields of products. The zinc terephthalate metal-organic framework catalyst could be recovered by a simple filtration and applied in consecutive runs with no significant decrease in the yield. The method was demonstrated to be a truly green process with economics and sustainability. (C) 2019 Elsevier B.V. All rights reserved.

Category: Triazoles. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Computed Properties of C2H4N4. Recently I am researching about NONGENOTOXIC CHEMICALS; RECOMMENDED LISTS; OXIDATIVE STRESS; FOLLOW-UP; ASSAY; PERFORMANCE; MUTAGENESIS; QUERCETIN; THRESHOLD; TESTS, Saw an article supported by the . Published in WILEY in HOBOKEN ,Authors: Allemang, A; De Abrew, KN; Shan, YQK; Krailler, JM; Pfuhler, S. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

A key step in the risk assessment process of a substance is the assessment of its genotoxic potential. Irrespective of the industry involved, current approaches rely on combinations of two or three in vitro tests and while highly sensitive, their specificity is thought to be limited. A refined in vitro genotoxicity testing strategy with improved predictive capacity would be beneficial and 3R friendly as it helps to avoid unnecessary in vivo follow-up testing. Here, we describe a proof of concept study evaluating a balanced set of compounds that have in vivo negative or positive outcomes, but variable in vitro data, to determine if we could differentiate between direct and indirect acting genotoxicants. Compounds were examined in TK6 cells using an approach in which the same sample was used to evaluate both early genomic markers (Affymetrix analysis 4 hr post treatment), and the genotoxic outcome (micronuclei [MN] after 24 hr). The resulting genomic data was then analyzed using the TGx-DDI biomarker, Connectivity mapping and whole genome clustering. Chemicals were also tested in the ToxTracker assay, which uses six different biomarker genes. None of the methods correctly differentiated all direct from indirect acting genotoxicants when used alone, however, the ToxTracker assay, TGx-DDI biomarker and whole genome approaches provided high predictive capacity when used in combination with the MN assay (1/18, 2/18, 1/18 missed calls). Ultimately, a fit for purpose combination will depend on the specific tools available to the end user, as well as considerations of the unique benefits of the individual assays.

Computed Properties of C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Allemang, A; De Abrew, KN; Shan, YQK; Krailler, JM; Pfuhler, S or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zohari, N; Mohammadkhani, FG in [Zohari, Narges; Mohammadkhani, Faezeh Ghiasvand] Malek Ashtar Univ Technol, Chem, Fac Chem & Chem Engn, Shahid Shaabanloo St, Tehran 158751774, Iran published Detonation Velocity Assessment of Energetic Cocrystals Using QSPR Approach in 2020.0, Cited 39.0. Computed Properties of C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In order to design a new energetic material with desirable performance, it is necessary to know its detonation performance. This study, exhibits a linear relationship between detonation velocity of energetic cocrystals and their molecular structure through quantitative structure property relationship (QSPR) method. The methodology of this research affords a new model which can relate the detonation velocity of energetic cocrystals to their several molecular structural descriptors. Moreover, this method supposes that the detonation velocity of energetic cocrystals is a function of n(N), Mw, n(C)/n(H), and n(O)/n(H). The new correlation is acquired on the basis of calculated data of detonation velocities of 40 cocrystals through reliable methods as training set. The R-2 or determination coefficient of the obtained correlation is 0.952. The new correlatoion provides an appropriate estimation for further 12 energetic cocrystals as test set. Meanwhile, the root mean square and average absolute deviation of a newly introduced correlation were found to be 0.398 and 0.308 km center dot s(-1), respectively. As a matter of fact, it is conceivable to design novel energetic cocrystals by the utility of the proposed correlation.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Category: Triazoles. I found the field of Chemistry very interesting. Saw the article Synthesis and properties of gem-dinitro energetic salts based on 1,2,4-oxadiazole with low impact sensitivity published in 2021.0, Reprint Addresses Chen, FX (corresponding author), Beijing Inst Technol, Sch Chem Sc Chem Engn, Liangxiang Campus,8 Liangxiang East Rd, Beijing 102488, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

Eight energetic salts with a gem-dinitro group based on 1,2,4-oxadiazole were developed. All of the structures were confirmed by infrared (IR) spectroscopy, H-1 and C-13 nuclear magnetic resonance (NMR) spectroscopy, and high-resolution mass spectrometry (HRMS), and single-crystal X-ray diffraction was used to determine the structures of the pivotal intermediate 3-(chlorodinitromethyl)-5-methyl-1,2,4-oxadiazole (3), the potassium salt (4) and the hydrazinium salt (7). All of them are insensitive to impact (>40 J) and have higher energy levels than trinitrotoluene (TNT).

Category: Triazoles. Welcome to talk about 61-82-5, If you have any questions, you can contact Lu, T; He, YN; Song, J; Hou, ZW; Yin, HQ; Fan, GJ; Chen, FX or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Selective adsorption and separation of C-2 hydrocarbons in a flexible-robust metal-organic framework based on a guest-dependent gate-opening effect WOS:000536127800010 published article about PROPANE in [Li, Jian-Rong] Beijing Univ Technol, Beijing Key Lab Green Catalysis & Separat, Coll Environm & Energy Engn, Beijing 100124, Peoples R China; Beijing Univ Technol, Dept Chem & Chem Engn, Coll Environm & Energy Engn, Beijing 100124, Peoples R China in 2020.0, Cited 31.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Formula: C2H4N4

The selective adsorption/separation of C-2 hydrocarbons has been realized in a flexible-robust MOF, Zn-2(Atz)(2)Ox. Owing to the distinctive guest-dependent multistep adsorption behaviors and suitable guest-framework interactions, this MOF shows outstanding separation performance for C2H2/C2H4 mixtures in a wide range of temperature confirmed by a column breakthrough experiment.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhang, PD; Wu, XQ; He, T; Xie, LH; Chen, Q; Li, JR or concate me.. Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019.0 J HETEROCYCLIC CHEM published article about FACILE SYNTHESIS; DERIVATIVES; EFFICIENT in [Sayed, Galal H.; Azab, Mohammad E.; Anwer, Kuris E.] Ain Shams Univ, Organ Chem Lab, Chem Dept, Fac Sci, Cairo 11566, Egypt in 2019.0, Cited 30.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Name: 1H-1,2,4-Triazol-5-amine

Under both conventional and microwave methods, 2-amino-4H-pyran-3-carbonitrile derivative 1 was synthesized and reacted with different reagents. Thus, 2-amino-4H-pyran-3-carbonitrile derivative was treated with chloroacetyl chloride, phenyl isocyanate, cyanoacetic acid, benzoyl chloride, triethyl orthoformate, acetic anhydride/H2SO4, arylidene malononitrile, urea, and/or p-aminosulphaguanidine producing chloroacetamide, 3-phenylurea, cyanoacetamide, N-benzoylpyran, ethylformimidate, pyranopyrimidin-4-one, pyranopyridine, pyranopyrimidin-2-one, and pyranopyrimidin-2-imine derivatives, respectively. Meanwhile, compound 1 was reacted with ethyl bromoacetate, phenacyl bromide, phthalic anhydride, different aromatic amines, and/or acetic acid/H2SO4 to produce 5-aminopyrano[2,3-b]pyrrole-6-carboxylate, dihydropyrano[2,3-b]pyrrole-6-yl-(phenyl)methanone, 1,3-dioxoisoindolinyl pyran, 1,4-dihydropyridine, and 2-hydroxy-1,4-dihydropyridine derivatives, respectively. On the other hand, when compound 1 was allowed to react with maleic anhydride and/or hydrazine hydrate, pyran-4-oxobut-2-enoic acid and 3-aminopyranopyrazole derivatives were obtained, respectively. Reaction of pyran-4-oxobut-2-enoic acid with malononitrile under different conditions gave 2-(furan-2-yl)-4H-pyran and 2-(4H-pyran-2-yl)-1H-pyrrole derivatives, while condensation of 3-aminopyranopyrazole with benzaldehyde gave 1,4-dihydropyrano[2,3-c]pyrazol-3-yl-1-phenylmethanimine derivative. The newly synthesized compounds were characterized by the spectroscopic tools IR, H-1-NMR, C-13-NMR, MS, and elemental analysis. Some of these compounds have been screened in vitro for antimicrobial activity against different strains of bacteria and fungi and also were tested against two cancer cell lines: mammary gland breast cancer (MCF-7) and colon cancer (HCT-118).

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Name: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Safety of 1H-1,2,4-Triazol-5-amine. In 2021.0 SYNTHETIC COMMUN published article about FAST-ATOM-BOMBARDMENT; BIGINELLI; 3-AMINO-1,2,4-TRIAZOLE; ANTICANCER in [Shvets, Elena H.; Pidvorotnia, Anastasiia, V; Kulyk, Olesia G.; Kolosov, Maksim A.] Kharkov Natl Univ, Sch Chem, UA-61022 Kharkiv, Ukraine; [Mazepa, Alexander, V] NAS Ukraine, AV Bogatsky Physicochem Inst, Odesa, Ukraine in 2021.0, Cited 31.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

4,7-Dihydroazolo[1,5-a]pyrimidin-5-ylmethanesulfonamides are side-products of the three-component Biginelli-like reaction of aminoazoles, aldehydes andN,N-dialkyl-2-ketomethanesulfonamides. Herein, we report a straightforward synthesis of 5-sulfonamidomethyl substituted 4,7-dihydroazolo[1,5-a]pyrimidines by a two-component condensation of aminoazoles andN,N-dialkyl(cinnamoyl)methanesulfonamides in DMF at reflux. The startingN,N-dialkyl-2-ketomethanesulfonamides can be obtained by either lithiation ofN,N-dialkylmethanesulfonamides and reaction with aldehydes followed by oxidation of the resulting alcohols or by Claisen condensation ofN,N-dialkylmethanesulfonamides with the corresponding esters. The chemical structures of all synthesized compounds are supported by(1)H and(13)C NMR-spectroscopy, mass spectrometry and elemental analysis.

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Shvets, EH; Pidvorotnia, AV; Kulyk, OG; Mazepa, AV; Kolosov, MA or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2020.0 MOL DIVERS published article about FUNCTIONALIZED MCM-41; BIOLOGICAL EVALUATION; DERIVATIVES in [Akrami, Sedigheh; Karami, Bahador; Farahi, Mahnaz] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran in 2020.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. HPLC of Formula: C2H4N4

Herein, an effectual, quick and novel method is described for the synthesis of new triazolo[1,5-a]pyrimidine, triazolo[5,1-b][1,3] thiazine and pyrazolo[1,5-a]pyrimidine derivatives. This series of fused six-member rings to triazole and pyrazole was prepared via the catalyst-free reaction of dialkyl acetylenedicarboxylates and 3-substituted 1H-1,2,4-triazole or 3-amino-1H-pyrazole-4-carbonitrile. The structures of the prepared products were deduced from their Fourier-transform infrared, elemental analysis and proton and carbon-13 nuclear magnetic resonance spectral data. Graphical abstract A novel and green method is described for the synthesis of new triazolo[1,5-a]pyrimidine, triazolo[5,1-b][1,3] thiazine and pyrazolo[1,5-a]pyrimidine derivatives. [GRAPHICS] .

HPLC of Formula: C2H4N4. Welcome to talk about 61-82-5, If you have any questions, you can contact Akrami, S; Karami, B; Farahi, M or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics