Why Are Children Getting Addicted To 1H-1,2,4-Triazol-5-amine

Welcome to talk about 61-82-5, If you have any questions, you can contact Liu, HJ; Dong, LB; Wang, M; Huang, GF or send Email.. HPLC of Formula: C2H4N4

Authors Liu, HJ; Dong, LB; Wang, M; Huang, GF in ROYAL SOC CHEMISTRY published article about RESONANCE ENERGY-TRANSFER; GOLD NANOCLUSTERS; FLUORESCENT SENSOR; RESIDUE; NANOCRYSTALS; PESTICIDES; CELLS; SERUM; PROBE; WATER in [Liu, Haijian; Dong, Libin; Wang, Miao; Huang, Guofu] Weifang Univ Sci & Technol, Shandong Peninsula Engn Res Ctr Comprehens Brine, Shouguang 262700, Weifang, Peoples R China; [Liu, Haijian; Huang, Guofu] Weifang Univ Sci & Technol, Weifang Key Lab Pollut Control & Resource Utiliza, Shouguang 262700, Weifang, Peoples R China in 2021.0, Cited 30.0. HPLC of Formula: C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Herein, a novel and sensitive fluorescence method for cartap determination is established on the basis of the inner filter effect (IFE) of gold nanoparticles (Au NPs) on the fluorescence of glutathione protected Cu NCs (GSH-Cu NCs). In the presence of Au NPs, the fluorescence of GSH-Cu NCs was strongly quenched by the IFE because the absorption spectra of Au NPs overlap well with the emission spectra of GSH-Cu NCs. Upon addition of cartap, cartap could induce the aggregation of Au NPs whose absorption spectrum does not overlap with the emission spectrum of GSH-Cu NCs. Then, with the increase in cartap concentration, the IFE-decreased fluorescence was gradually recovered, realizing the fluorescence sensing of cartap. Under optimal conditions, the proposed method has a good linear relationship with cartap concentration in the range of 7-100 nM, and the detection limit is 3.34 nM. In addition, satisfactory results were obtained for cartap analysis using tap water and cabbage as real samples, which demonstrated that the method as-developed would have great practical application prospects.

Welcome to talk about 61-82-5, If you have any questions, you can contact Liu, HJ; Dong, LB; Wang, M; Huang, GF or send Email.. HPLC of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

When did you first realize you had a special interest and talent in1H-1,2,4-Triazol-5-amine

Welcome to talk about 61-82-5, If you have any questions, you can contact Abdollahi-Basir, MH; Shirini, F; Tajik, H; Ghasemzadeh, MA or send Email.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Recently I am researching about METAL-ORGANIC FRAMEWORKS; IONIC LIQUID; INHIBITORS; DESIGN; DERIVATIVES; EFFICIENT; POTENT; WATER; ACID, Saw an article supported by the . Published in ELSEVIER SCIENCE BV in AMSTERDAM ,Authors: Abdollahi-Basir, MH; Shirini, F; Tajik, H; Ghasemzadeh, MA. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Zinc terephthalate metal-organic framework catalyzed one-pot, three-component reaction of 3-amino-1H-1,2,4-triazoles, aromatic aldehydes and barbituric acid to prepare some new pyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidinediones. The reactions conducted under ultrasonic irradiation and solvent-free conditions with good to excellent yields of products. The zinc terephthalate metal-organic framework catalyst could be recovered by a simple filtration and applied in consecutive runs with no significant decrease in the yield. The method was demonstrated to be a truly green process with economics and sustainability. (C) 2019 Elsevier B.V. All rights reserved.

Welcome to talk about 61-82-5, If you have any questions, you can contact Abdollahi-Basir, MH; Shirini, F; Tajik, H; Ghasemzadeh, MA or send Email.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Top Picks: new discover of 1H-1,2,4-Triazol-5-amine

Welcome to talk about 61-82-5, If you have any questions, you can contact Szennyes, E; Bokor, E; Docsa, T; Sipos, A; Somsak, L or send Email.. Safety of 1H-1,2,4-Triazol-5-amine

Safety of 1H-1,2,4-Triazol-5-amine. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Synthesis of C-beta-D-glucopyranosyl derivatives of some fused azoles for the inhibition of glycogen phosphorylase published in 2019.0, Reprint Addresses Bokor, E; Somsak, L (corresponding author), Univ Debrecen, Dept Organ Chem, POB 400, H-4002 Debrecen, Hungary.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

Annulated C-beta-D-glucopyranosyl heterocycles were synthesized and tested as inhibitors of glycogen phosphorylase. 2-(beta-D-Glucopyranosyl)-1H-imidazo[4,5-b] pyridine was formed by ring-closure of O-perbenzoylated C-beta-D-glucopyranosyl formic acid with 2,3-diaminopyridine in the presence of triphenylphosphite. Cyclisations of bromomethyl 2,3,4,6-tetra-O-benzoyl-beta-D-glucopyranosyl ketone with a set of 2-aminoheterocycles resulted in constitutionally reversed C-beta-D-glucopyranosyl imidazoles fused by pyridine, pyrimidine, thiazole, 1,3,4-thiadiazole, benzothiazole and benzimidazole. O-Debenzoylation of the above compounds was effected by standard transesterification to get the test compounds. The 1H-imidazo[4,5-b] pyridine proved to be a low micromolar inhibitor (K-i = 21.1 mu M) of rabbit muscle glycogen phosphorylase b, while the other heterocycles displayed weak or no inhibition against the same enzyme.

Welcome to talk about 61-82-5, If you have any questions, you can contact Szennyes, E; Bokor, E; Docsa, T; Sipos, A; Somsak, L or send Email.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Why Are Children Getting Addicted To 61-82-5

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1H-1,2,4-Triazol-5-amine

In 2020.0 J HETEROCYCLIC CHEM published article about BIOLOGICAL EVALUATION; DERIVATIVES; DESIGN; FLUORESCENCE; INSIGHT; HYBRIDS in [El-Gohary, Nasser M.; El-Kazak, Azza M.; Ibrahim, Magdy A.] Ain Shams Univ, Fac Educ, Dept Chem, Cairo 11711, Egypt in 2020.0, Cited 33.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Safety of 1H-1,2,4-Triazol-5-amine

Polyfunctional 3-chloro-3-(4-chlorocoumarin-3-yl)prop-2-enal (1) used as a precursor for heterocyclic synthesis. Dichloro-aldehyde 1 was allowed to react with variable nucleophilic reagents, and a diversity of heterocyclic systems linked coumarin moiety at position 3 was synthesized. The reaction of compound 1 with guanidine and cyanoguanidine produced 3-(pyrimidin-4-yl)-4-chlorocoumarins 2 and 3. Treating compound 1 with 3-amino-1,2,4-triazole and 2-aminobenzimidazole yielded triazolo[4,3-a]pyrimidine 4 and pyrimido[1,2-a]benzimidazole 5. The treatment of compound 1 with cyanoacetamide, N-benzyl-2-cyanoacetamide, and 1H-benzimidazolylacetonitrile gave 2(1H)-pyridones 6, 7 and pyrido[1,2-a]benzimidazole 8. The reaction of compound 1 with 5-amino-3-methyl-1H-pyrazole and 6-aminouracil afforded pyrazolo[3,4-b]pyridine 9 and pyrido[2,3-d]pyrimidine 10, respectively. Compound 1 reacted with ethylenediamine, o-phenylenediamine, o-aminophenol, and o-aminothiophenol leading to 5-(imidazolylmethyl)chromeno[4,3-e] [1,4]diazepine (12), 3-(benzodiazepin/benzoxazepin-2-yl)-4-chlorocoumarins 13, 14, and 6-(benzothiazol-2-ylmethyl)chromeno[4,3-b][1,5]benzothiazepine 16, respectively. Structures of the new synthesized products were deduced on the basis of their analytical and spectral data.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

New learning discoveries about C2H4N4

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Formula: C2H4N4

In 2021 J ANAL APPL PYROL published article about SECOIRIDOID GLUCOSIDES; ANTIBACTERIAL ACTIVITY; CHEMICAL-COMPOSITION; PYROLYSIS; PRODUCT; BIOMASS; MOLECULES; OIL; ANTIOXIDANT; COMPONENTS in [Gu, Haiping; Lam, Su Shiung; Yue, Xiaochen; Yang, Jun; Peng, Wanxi] Henan Agr Univ, Henan Prov Engn Res Ctr Biomass Value Added Prod, Zhengzhou 450002, Peoples R China; [Foong, Shin Ying; Lam, Su Shiung] Univ Malaysia Terengganu, Inst Trop Aquaculture & Fisheries Akuatrop, Pyrolysis Technol Res Grp, Terengganu 21030, Malaysia in 2021, Cited 75. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Formula: C2H4N4

Utilization of lignocellulosic biomass is increasingly important. Jasminum nudiflorum Lindl. (JNL) is a widely cultivated landscape plant in China. To evaluate the chemical components, pyrolysis characteristics as well as the potential values of JNL bark for utilization, the components were extracted using methanol, ethanol, and benzene/ethanol (2:1, v/v) and pyrolyzed from room temperature to 300 ?C, respectively. Many components were detected in the extracts and the pyrolyzates of JNL bark and their chemical properties were analyzed. The compounds identified in the extracts and the pyrolyzates of JNL bark included acids, aldehydes, alcohols, esters, ketones, aromatics, saccharides, olefins, and nitrogen-containing compounds. Some of the identified compounds, such as urs-12-en-28-al, 3-(acetyloxy)-, (3.beta.)-, 5-hydroxymethylfurfural, and vanillin, are widely used in the medical, energy, and food industries. The pyrolysis of JNL bark using thermogravimetric (TG) analyzer showed the highest reaction rate occurred at between 200 and 300 ?C where the maximum mass loss was observed. According to the Coats-Redfern method, the calculated apparent activation energy (E) and pre-exponential factor (A) of the pyrolysis process of JNL bark were 52.04 kJ mol- 1 and 3.14 ? 105 min-1, respectively. This research provides information on the components and pyrolysis characteristics of JNL bark, which shows great potential for application in medical, food, and chemical industries.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

The Best Chemistry compound:1H-1,2,4-Triazol-5-amine

SDS of cas: 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Jahanshahi, P; Mamaghani, M or send Email.

I found the field of Chemistry very interesting. Saw the article Efficient and straightforward access to diverse and densely functionalized chromenes by 3-amino-1,2,4-triazole supported on hydroxyapatite-encapsulated-gamma-Fe2O3(gamma-Fe2O3@HAp@CPTMS@AT) as a new magnetic basic nanocatalyst published in 2020.0. SDS of cas: 61-82-5, Reprint Addresses Mamaghani, M (corresponding author), Univ Guilan, Dept Chem, Fac Sci, POB 41335-1914, Rasht, Iran.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

A highly efficient and straightforward one-pot three-component synthesis of functionalized 2-amino-4H-chromenes and indole-substituted 3-amino-1H-benzo[f]chromenes have been developed by 3-amino-1,2,4-triazole supported on hydroxyapatite-encapsulated-gamma-Fe2O3(gamma-Fe2O3@HAp@CPTMS@AT) as the new magnetically recyclable heterogeneous basic nanocatalyst. The wide range of valuable 4H-chromene and 1H-chromene structures having different substituents were efficiently synthesized using one-pot tandem Knoevenagel cyclocondensation reaction of aromatic aldehydes, active methylene nitriles (malononitrile and 3-cyanoacetylindole) and diverse phenolic nucleophiles (resorcinol, alpha-naphthol and beta-naphthol) in the presence of nano gamma-Fe2O3@HAp@CPTMS@AT in EtOH. The structure and morphology of the synthesized nanocatalyst were characterized by using various techniques such as FT-IR, FESEM, EDS, XRD, TGA-DTA and VSM. The catalytic activity of nano gamma-Fe2O3@HAp@CPTMS@AT was evaluated and the results indicated its applicability as a novel, highly efficient, green, recyclable and promising heterogeneous basic nanocatalyst for the synthesis of 4H-chromene and 1H-chromene derivatives.

SDS of cas: 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Jahanshahi, P; Mamaghani, M or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

When did you first realize you had a special interest and talent in61-82-5

Recommanded Product: 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Mekky, AEM; Sanad, SMH; Ahmed, AAM or send Email.

Recently I am researching about DIHYDROOROTATE DEHYDROGENASE; ANTIMICROBIAL EVALUATION; BIOLOGICAL EVALUATION; BRIDGEHEAD NITROGEN; SMALL-MOLECULE; DERIVATIVES; DISCOVERY; DESIGN; BENZOTHIAZOLE; BENZIMIDAZOLE, Saw an article supported by the . Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Mekky, AEM; Sanad, SMH; Ahmed, AAM. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine. Recommanded Product: 61-82-5

Novel bis[(thiazol-2-yl)acetonitrile] derivatives were prepared in good yields by the cyclocondensation of bis(bromoacetyl) derivatives with two equivalents of 2-cyanothioacetamide in dioxane at reflux. The bis[(thiazol-2-yl)acetonitrile] derivatives were taken as synthetic precursors for the synthesis of novel bis(aminoazolo[1,5-a]pyrimidines), bearing thiazole moiety. The target molecules were prepared by the three component one pot reaction of bis[(thiazol-2-yl)acetonitrile] derivatives, dimethylformamide-dimethylacetal and several of 3-aminopyrazoles in pyridine under microwave irradiation at 140 degrees C for 2 h. Using the same protocol, novel bis(aminotriazolo[1,5-a]pyrimidines), bis(aminopyrimido[1,2-a]benzimidazoles) and bis(aminopyrido [1,2-a]benzimidazoles), incorporating thiazole moieties, were prepared by using the appropriate heterocyclic amine or 2-(1H-benzoimidazol-2-yl)acetonitrile instead of 3-aminopyrazoles. The structure of the newly prepared thiazoles was confirmed via considering their elemental analyses and spectral data.

Recommanded Product: 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Mekky, AEM; Sanad, SMH; Ahmed, AAM or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

What I Wish Everyone Knew About 61-82-5

Welcome to talk about 61-82-5, If you have any questions, you can contact Dogra, S; Kar, AK; Girdhar, K; Daniel, PV; Chatterjee, S; Choubey, A; Ghosh, S; Patnaik, S; Ghosh, D; Mondal, P or send Email.. Quality Control of 1H-1,2,4-Triazol-5-amine

Dogra, S; Kar, AK; Girdhar, K; Daniel, PV; Chatterjee, S; Choubey, A; Ghosh, S; Patnaik, S; Ghosh, D; Mondal, P in [Dogra, Surbhi; Girdhar, Khyati; Daniel, P. Vineeth; Chatterjee, Swarup; Choubey, Abhinav; Ghosh, Subrata; Mondal, Prosenjit] Indian Inst Technol Mandi, Sch Basic Sci, Mandi, Himachal Prades, India; [Kar, Aditya K.; Patnaik, Satyakam; Ghosh, Debabrata] ITTR, CSIR, Lucknow, Uttar Pradesh, India published Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis in 2019.0, Cited 29.0. Quality Control of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Insulin resistance is thought to be a common link between obesity and Non-Alcoholic Fatty Liver Disease (NAFLD). NAFLD has now reached epidemic status worldwide and identification of molecules or pathways as newer therapeutic strategies either to prevent or overcome insulin resistance seems critical. Dysregulated hepatic lipogenesis (DNL) is a hallmark of NAFLD in humans and rodents. Therefore, reducing DNL accretion may be critical in the development of therapeutics of NAFLD. In our in vivo model (high-fat-diet fed [HFD] obese mice) we found Zinc oxide nanoparticles (ZnO NPs) significantly decreased HFD-induced hepatic steatosis and peripheral insulin resistance. This protective mechanism of ZnO NPs was signaled through hepatic SIRT1-LKB1-AMPK which restricted SREBP-lc within the cytosol limiting its transcriptional ability and thereby ameliorating HFD mediated DNL. These observations indicate that ZnO NP can serve as a therapeutic strategy to improve the physiological homeostasis during obesity and its associated metabolic abnormalities. (C) 2019 Elsevier Inc. All rights reserved.

Welcome to talk about 61-82-5, If you have any questions, you can contact Dogra, S; Kar, AK; Girdhar, K; Daniel, PV; Chatterjee, S; Choubey, A; Ghosh, S; Patnaik, S; Ghosh, D; Mondal, P or send Email.. Quality Control of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

The Best Chemistry compound:61-82-5

Category: Triazoles. Welcome to talk about 61-82-5, If you have any questions, you can contact Zhou, SH; Xu, HB; Wei, YJ; Gao, J; Feng, Y; Wang, N; Gao, JF or send Email.

I found the field of Science & Technology – Other Topics; Materials Science; Physics very interesting. Saw the article Platelet Nitrogen and Sulfur Co-Doped Ordered Mesoporous Carbon with Inexpensive Methylene Blue as a Single Precursor for Electrochemical Detection of Herbicide Amitrole published in 2019.0. Category: Triazoles, Reprint Addresses Zhou, SH; Xu, HB (corresponding author), Hebei Normal Univ Nationalities, Dept Chem & Chem Engn, Chengde 067000, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Heteroatom-doped ordered mesoporous carbons (OMCs) have currently been considered as promising electrode materials for electrochemical sensors due to the combined advantages of ordered mesoporous materials and heteroatom-doped carbon materials. Herein, a novel nitrogen and sulfur co-doped OMCs (N,S-OMC) has been prepared via a nanocasting strategy with an inexpensive methylene blue as single precursor. The obtained mesoporous carbon has platelet morphology, short mesoporous channel together with a large surface area (549 m(2)/g) as well as rich N- and S-containing functional groups (6.8 at.% N and 2.3 at.% S). Compared with the graphene (GR) and carbon nanotube (CNT) electrode material, the N,S-OMC exhibited a higher electrochemical activity towards the oxidation of herbicide amitrole, ascribable to N,S-OMC’s open mesoporous structures and abundant electroactive defect sites on the carbon skeleton. And, an amitrole electrochemical sensor with N,S-OMC modified electrode as working electrode was fabricated, exhibiting a good selectivity, stability, reproducibility and wide linear range of 3-750 mu M. Moreover, the N,S-OMC-based electrochemical sensor was proved feasible in river water sample analyses, showing a satisfied recovery ranging from 97.03% to 105.42%. The results not only demonstrate cheap methylene blue can be used as single precursor for the N,S-OMC preparation, but also confirm the N,S-OMC is promising in amitrole sensor fabrication.

Category: Triazoles. Welcome to talk about 61-82-5, If you have any questions, you can contact Zhou, SH; Xu, HB; Wei, YJ; Gao, J; Feng, Y; Wang, N; Gao, JF or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Awesome and Easy Science Experiments about C2H4N4

Welcome to talk about 61-82-5, If you have any questions, you can contact Landin, EJB; Lovera, S; de Fabritiis, G; Kelm, S; Mercier, J; McMillan, D; Sessions, RB; Taylor, RJ; Sands, ZA; Joedicke, L; Crump, MP or send Email.. Computed Properties of C2H4N4

Computed Properties of C2H4N4. Landin, EJB; Lovera, S; de Fabritiis, G; Kelm, S; Mercier, J; McMillan, D; Sessions, RB; Taylor, RJ; Sands, ZA; Joedicke, L; Crump, MP in [Landin, Erik J. B.; Crump, Matthew P.] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England; [Kelm, Sebastian; McMillan, David; Taylor, Richard J.; Joedicke, Lisa] UCB Celltech, 216 Bath Rd, Slough SL1 3WE, Berks, England; [Lovera, Silvia; Mercier, Joel; Sands, Zara A.] UCB Biopharma, 1 Chemin Foriest, B-1420 Braine Lalleud, Belgium; [de Fabritiis, Gianni] Acellera, Barcelona Biomed Res Pk PRBB,C Doctor Aiguader 88, Barcelona 08003, Spain; [de Fabritiis, Gianni] Passeig Lluis Co 23, ICREA, Barcelona 08010, Spain; [Sessions, Richard B.] Univ Bristol, Biomed Sci, Bristol BS8 1TD, Avon, England published The Aminotriazole Antagonist Cmpd-1 Stabilises a Distinct Inactive State of the Adenosine 2A Receptor in 2019.0, Cited 25.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

The widely expressed G-protein coupled receptors (GPCRs) are versatile signal transducer proteins that are attractive drug targets but structurally challenging to study. GPCRs undergo a number of conformational rearrangements when transitioning from the inactive to the active state but have so far been believed to adopt a fairly conserved inactive conformation. Using (FNMR)-F-19 spectroscopy and advanced molecular dynamics simulations we describe a novel inactive state of the adenosine 2A receptor which is stabilised by the aminotriazole antagonist Cmpd-1. We demonstrate that the ligand stabilises a unique conformation of helix V and present data on the putative binding mode of the compound involving contacts to the transmembrane bundle as well as the extracellular loop 2.

Welcome to talk about 61-82-5, If you have any questions, you can contact Landin, EJB; Lovera, S; de Fabritiis, G; Kelm, S; Mercier, J; McMillan, D; Sessions, RB; Taylor, RJ; Sands, ZA; Joedicke, L; Crump, MP or send Email.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics