Tag: M.W=0-100

Qu, L; Li, HL; Guo, D; Wang, Y; Zhu, JH; Yin, LY; Peng, SQ in [Qu, Long; Yin, Li-Yan] Hainan Univ, Sch Life & Pharmaceut Sci, Haikou 570228, Hainan, Peoples R China; [Qu, Long; Li, Hui-Liang; Guo, Dong; Wang, Ying; Zhu, Jia-Hong; Peng, Shi-Qing] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, 4 Xueyuan Rd, Haikou 571101, Hainan, Peoples R China published HbWRKY27, a group IIe WRKY transcription factor, positively regulates HbFPS1 expression in Hevea brasiliensis in 2020.0, Cited 46.0. Recommanded Product: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Farnesyl pyrophosphate synthase (FPS) is a key enzyme that catalyzes the formation of farnesyl pyrophosphate, the main initiator for rubber chain initiation in Hevea brasiliensis Muell. Arg. The transcriptional regulatory mechanisms of the FPS gene still not well understood. Here, a WRKY transcription factor designated HbWRKY27 was obtained by screening the latex cDNA library applied the HbFPS1 promoter as bait. HbWRKY27 interacted with the HbFPS1 promoter was further identified by individual Y1H and EMSA assays. HbWRKY27 belongs to group IIe WRKY subfamily which contains a typical WRKY domain and C-X5-CX23-HXH motif. HbWRKY27 was localized to the nucleus. HbWRKY27 predominantly accumulated in latex. HbWRKY27 was up-regulated in latex by ethrel, salicylic acid, abscisic acid, and methyl jasmonate treatment. Transient expression of HbWRKY27 led to increasing the activity of the HbFPS1 promoter in tobacco plant, suggesting that HbWRKY27 positively regulates the HbFPS1 expression. Taken together, an upstream transcription factor of the key natural rubber biosynthesis gene HbFPS1 was identified and this study will provide novel transcriptional regulatory mechanisms of the FPS gene in Hevea brasiliensis.

Welcome to talk about 61-82-5, If you have any questions, you can contact Qu, L; Li, HL; Guo, D; Wang, Y; Zhu, JH; Yin, LY; Peng, SQ or send Email.. Recommanded Product: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article A new and green approach for regiospecific synthesis of novel chromeno-triazolopyrimidin using tungstic acid immobilized MCM-41 as a reusable catalyst WOS:000539021400012 published article about FUNCTIONALIZED MCM-41; SILICA; NANOPARTICLES; COUMARIN; POTENT in [Akrami, Sedigheh; Karami, Bahador; Farahi, Mahnaz] Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran in 2020.0, Cited 40.0. HPLC of Formula: C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A novel, eco-friendly and fast route has been developed for the synthesis of new and known triazolo[1,5-a]pyrimidin fused chromone derivatives via a one pot three-component reaction of 3-amino-1,2,4-triazoles, aromatic aldehydes and 4-hydroxycoumarin in aqueous medium at room temperature. These reactions are catalyzed by MCM-41-HWO4 as a safe and recyclable mesoporous solid acid. It combines successfully the synergistic effect of green chemistry with nanocatalysis. The yields are high and the products were characterized by H-1 NMR, (CNMR)-C-13 spectra and elemental analysis.

Welcome to talk about 61-82-5, If you have any questions, you can contact Akrami, S; Karami, B; Farahi, M or send Email.. HPLC of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase WOS:000552629800008 published article about GROWTH-FACTOR RECEPTOR-2; BIOLOGICAL EVALUATION; ANTICANCER EVALUATION; INHIBITORS; ANGIOGENESIS; RESISTANCE; MECHANISM; DISCOVERY; DESIGN in [Dawood, Dina H.] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Pharmaceut & Drug Ind Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt; [Nossier, Eman S.] Al Azhar Univ, Fac Pharm Girls, Dept Pharmaceut Chem, POB 11754, Cairo, Egypt; [Ali, Mamdouh M.; Mahmoud, Abeer E.] Natl Res Ctr, Biochem Dept, Genet Engn & Biotechnol Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt in 2020.0, Cited 50.0. Category: Triazoles. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Based on the previous studies that revealed the valuable role of pyrazole scaffold in cancer management and VEGFR-2 inhibition, a new set of pyrazole conjugated with pyrazoline, triazolopyrimidine and pyrazolone moieties were synthesized and investigated for their anticancer efficiency against human breast cancer MCF-7. The anticancer screening revealed the significant sensitivity of breast carcinoma towards compounds 4b, 5c, 6c, 7b, 7c and 12c with IC50 values ranging from 16.50 – 26.73 mu M in comparison with tamoxifen (IC50 = 23.31 mu M). Moreover, the new analogues were further examined for their VEGFR-2 inhibitory activity, among the tested derivatives 5c, 6c, 7b, 7c and 12c displayed prominent inhibitory efficiency versus VEGFR-2 kinase with % inhibition ranging from 70 to 79%. Compounds 6c, 7c and 12c revealed inhibitory efficiency in nanomolar level with IC50 (913.51, 225.17 and 828.23 nM, respectively) comparing to sorafenib (IC50 = 186.54 nM). Flow cytometric analysis revealed that the promising compound 12c prompted pre-G1 apoptosis and cell growth cessation at G2/M phase and stimulated apoptosis via activation of caspase-3. Moreover, molecular docking study of the promising derivatives was performed to highlight their binding modes and interactions with the amino acid residues of VEGFR-2 enzyme.

Category: Triazoles. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 1H-1,2,4-Triazol-5-amine. In 2019.0 INT J MOL SCI published article about HISTONE H2AX; BRCT DOMAINS; S-PHASE; DNA; PROTEIN; REPAIR; MDC1; LOCALIZATION; LIGASE; REGION in [Krieger, Kimiko L.; Hu, Wen-Feng; Ripperger, Tyler; Woods, Nicholas T.] Univ Nebraska Med Ctr, Fred & Pamela Buffett Canc Ctr, Eppley Inst Res Canc & Allied Dis, Omaha, NE 68198 USA; [Hu, Wen-Feng] Univ Nebraska Med Ctr, Coll Med, Dept Emergency Med, Omaha, NE 68198 USA; [Ripperger, Tyler] Univ Arizona, Dept Immunobiol, Coll Med, Tucson, AZ 85724 USA in 2019.0, Cited 43.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Deleterious mutations in Breast Cancer 1 (BRCA1) are associated with an increased risk of breast and ovarian cancer. Mutations in the tandem BRCA1 C-terminal (tBRCT) protein domain disrupt critical protein interactions required for the faithful repair of DNA through homologous recombination, which contributes to oncogenesis. Our studies have identified RICTOR, PRR5, and SIN1 subunits of the mammalian target of rapamycin complex 2 (mTORC2) as interacting partners with the tBRCT domain of BRCA1 leading to the disruption of the mTORC2 complex. However, the interplay between mTORC2 signaling and BRCA1 function in the DNA damage response (DDR) remains to be determined. In this study, we used protein interaction assays to determine the binary interactions between the tBRCT domain and mTORC2 subunits, evaluated the impact of mTOR inhibition on the transcriptional function of the tBRCT, evaluated the impact of mTOR signaling on BRCA1 recruitment to DNA damage-induced foci and determined the breast cancer cell line response to mTOR inhibition dependent upon BRCA1 expression and mutation. This study determined that PRR5, RICTOR, and SIN1 could each independently interact with the BRCA1 tBRCT. Inhibition of mTORC1, but not mTORC1/2, increases BRCA1 transcriptional activation activity. Treatment with pan-mTOR inhibitor PP242 diminishes DNA damage-induced gamma H2AX and BRCA1 foci formation. Breast cancer cells lacking expression of functional BRCA1 are more sensitive to mTOR inhibitors. These data suggest that mTOR signaling is required for BRCA1 response to DNA damage and breast cancer cells lacking BRCA1 are more sensitive to pan-mTOR inhibition. This work suggests chemotherapeutic strategies using mTOR inhibitors could be tailored for patients that lack functional BRCA1.

Welcome to talk about 61-82-5, If you have any questions, you can contact Krieger, KL; Hu, WF; Ripperger, T; Woods, NT or send Email.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Authors Chen, Y; Chen, YH; Zhang, YJ; Zhang, DP; Li, GM; Wei, JL; Hua, X; Lv, B; Liu, LJ in TAYLOR & FRANCIS INC published article about in [Chen, Yun; Liu, Lijun] Yangzhou Univ, Jiangsu Key Lab Crop Genet & Physiol, Jiangsu Coinnovat Ctr Modern Prod Technol Grain C, Jiangsu Key Lab Crop Genom & Mol Breeding, Yangzhou, Jiangsu, Peoples R China; [Chen, Yun; Chen, Yuanhua; Zhang, Yajun; Zhang, Dongping; Li, Guoming; Wei, Jiali; Hua, Xia; Lv, Bing] Yangzhou Univ, Coll Biosci & Biotechnol, Yangzhou, Jiangsu, Peoples R China in 2021.0, Cited 49.0. Recommanded Product: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Heterotrimeric G-protein a and beta-subunits regulate H2O2-mediated aerenchyma formation. The rice G-protein gamma-subunit, dense and erect panicle 1 (DEP1), is known to interact with the a-subunit and regulate nitrogen utilization and yield. However, it is unclear whether DEP1 regulates cell death for aerenchyma formation in rice roots. Using wild-type WYJ8 and its transgenic line WYJ8(DEPJ), we confirmed that DEP1 is involved in H2O2-mediated aerenchyma formation. The rates of aerenchyma formation varied in different parts of the roots in both varieties, with the highest rate in the 4-7 cm segments, reaching a plateau in the 7-8 cm segments. Compared with WYJ8, the aerenchyma area and H2O2 content in WYJ8(DEP1) were increased by 55.98% and 53.37%, respectively; however, the responses of aerenchyma formation to exogenous H2O2 were basically the same in the two varieties. Diphenylene iodonium (DPI) treatment had no effect on H2O2 production and elimination processes in WYJ8, but significantly reduced the activity of the key enzyme that catalyzes H2O2 biosynthesis in WYJ8(DEP1). Importantly, exogenous H2O2 treatment did not offset the effect of the decrease in endogenous H2O2 level caused by DPI on aerenchyma formation. These results indicated that DEP1 enhanced H2O2 biosynthesis and promoted the cell death of the root cortex, thus contributing to aerenchyma development in WYJ8(DEP1).

Recommanded Product: 61-82-5. Welcome to talk about 61-82-5, If you have any questions, you can contact Chen, Y; Chen, YH; Zhang, YJ; Zhang, DP; Li, GM; Wei, JL; Hua, X; Lv, B; Liu, LJ or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Safety of 1H-1,2,4-Triazol-5-amine. Zubir, M; Nasutioni, HI; Sudarma, TF in [Zubir, Moondra; Nasutioni, Hafni Indriati] State Univ Medan, Fac Math & Nat Sci, Chem Dept, Jl Willem Iskandar,Pasar 5,Medan Estate, Medan 20221, North Sumatera, Indonesia; [Sudarma, Teguh Febri] State Univ Medan, Fac Math & Nat Sci, Phys Dept, Jl Willem Iskandar,Pasar 5,Medan Estate, Medan 20221, North Sumatera, Indonesia published The Role of Micropores and Amino Groups in Preferential CO2 Adsorptivity of Porous Zn-Coordination Polymers Comprising Mixed Ligands of Triazole and Amino Triazole in 2019.0, Cited 18.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Porous coordination polymers (PCPs) of Zn2+, oxalic acid and mixture ratio of 3-amino, 1,2,4-triazole (Ataz) and 1,2,4-triazole (Taz) were synthesized to capture of carbon dioxide. A series of molar fraction Taz/(Taz + ATaz) prepared as 0.1;0.3;0.4;0.5;0.6;0.7 and 0.9 and also only ATaz and Taz ligand as 0 and 1 molar fraction respectively. Mixture of Taz and ATaz crystal induce new structure of 0.4, 0.5 and 0.6 molar fraction. Nitrogen adsorption of 50% mixture each ligand contribute the highest surface area as function of optimum condition to integrate pore space and amine group presence with adsorbed as 290 mgg(-1). This phenomena also shown through CO2 adsorption amount as 135 mgg(-1), instead of 0.4, 0.6 and 0.7 molar fraction observed higher amount of CO2 compared with only Taz ligand (X=1), indicate the integrated effects both of the ligand could generated the capture of higher amount of carbon dioxide.

Welcome to talk about 61-82-5, If you have any questions, you can contact Zubir, M; Nasutioni, HI; Sudarma, TF or send Email.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Dual-signal aptamer sensor based on polydopamine-gold nanoparticles and exonuclease I for ultrasensitive malathion detection WOS:000461341700052 published article about ORGANOPHOSPHORUS PESTICIDES; ELECTROCHEMICAL APTASENSOR; MASS-SPECTROMETRY; DNA APTAMER; BIOSENSOR; RESIDUES; SAMPLES; ACID; MICROEXTRACTION; EXTRACTION in [Xu, Guoli; Zhao, Yanan; Bao, Jing; Yang, Mei; Yang, Yixia; Li, Li; Huo, Danqun; Hou, Changjun] Chongqing Univ, Key Lab Biorheol Sci & Technol, State & Local Joint Engn Lab Vasc Implants, Minist Educ,Bioengn Coll, Chongqing 400044, Peoples R China; [Hou, Jingzhou] Chongqing Univ, Key Lab Ecoenvironm Three Gorges Reg, Fac Urban Construct & Environm Engn, Minist Educ, Chongqing 400045, Peoples R China; [Fa, Huanbao] Chongqing Univ, Coll Chem & Chem Engn, Chongqing 400044, Peoples R China in 2019.0, Cited 56.0. Safety of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A highly sensitive dual-signal aptamer sensor based on polydopamine-gold nanoparticles (PDA-AuNPs) and exonuclease I (Exo I) was developed for detection of malathion. Compared with traditional sensing elements, aptamer has many advantages, such as high affinity, superior specificity, strong stability and easy modification. The electrodeposition synthesis of PDA-AuNPs gave excellent biocompatibility and electrical conductivity on the sensor. With the addition of malathion, the specific interaction between malathion and its aptamer forced the aptamer to detach from the electrode surface and induced the capture probe to form a hairpin structure on the electrode surface. Exo I was added to motivate the autocatalytic target cycling which remarkably increased the current change of electrochemical signal over 2 times. Therefore, the promising strategy gave rise to an optional dual-signal current readout in both the signal-on of Fc and the signal-off of Tn. In this work, the prepared biosensor exhibited high sensitivity to malathion via the combination of dual-signal design and autocatalytic target cycling amplification. Under the optimized conditions, the proposed sensor showed a wide linear range from 0.5 to 600 ng/L malathion. It also exhibited excellent specificity, acceptable repeatability and good stability. The application of real samples obtained satisfactory recovery results, demonstrating a promising potential in food safety analysis.

Safety of 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact Xu, GL; Hou, JZ; Zhao, YN; Bao, J; Yang, M; Fa, HB; Yang, YX; Li, L; Huo, DQ; Hou, CJ or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Redenti, S; Marcovich, I; De Vita, T; Perez, C; De Zorzi, R; Demitri, N; Perez, DI; Bottegoni, G; Bisignano, P; Bissaro, M; Moro, S; Martinez, A; Storici, P; Spalluto, G; Cavalli, A; Federico, S in [Redenti, Sara; Marcovich, Irene; De Zorzi, Rita; Spalluto, Giampiero; Federico, Stephanie] Univ Trieste, Dept Chem & Pharmaceut Sci, Via Licio Giorgeri 1, I-34127 Trieste, Italy; [De Vita, Teresa; Cavalli, Andrea] Ist Italiano Tecnol, Drug Discovery & Dev D3, Via Morego 30, I-16163 Genoa, Italy; [Perez, Concepcion; Perez, Daniel I.; Martinez, Ana] CSIC, Ctr Invest Biol, Ave Ramiro Maeztu 9, Madrid 28040, Spain; [Demitri, Nicola; Storici, Paola] Elettra Sincrotrone Trieste SCpA, SS 14,Km 163-5,AREA Sci Pk, I-34149 Trieste, Italy; [Bottegoni, Giovanni] Univ Birmingham, Sir Robert Aitken Inst Med Res, Coll Med & Dent Sci, Sch Pharm,Inst Clin Sci, Edgbaston B15 2TT, England; [Bisignano, Paola] Univ Calif San Francisco, Cardiovasc Res Inst, 555 Mission Bay Blvd South, San Francisco, CA 94158 USA; [Bissaro, Maicol; Moro, Stefano] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Mol Modeling Sect, Via Marzolo 5, I-35131 Padua, Italy published A Triazolotriazine-Based Dual GSK-3 beta/CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition in 2019.0, Cited 33.0. HPLC of Formula: C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Glycogen synthase kinase 3 beta (GSK-3 beta) and casein kinase 1 delta (CK-1 delta) are emerging targets for the treatment of neuroinflammatory disorders, including Parkinson’s disease. An inhibitor able to target these two kinases was developed by docking-based design. Compound 12, 3-(7-amino-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl)-2-cyanoacrylamide, showed combined inhibitory activity against GSK-3 beta and CK-1 delta [IC50(GSK-3 beta)=0.17 mu m; IC50(CK-1 delta)=0.68 mu m]. In particular, classical ATP competition was observed against CK-1 delta, and a co-crystal of compound 12 inside GSK-3 beta confirmed a covalent interaction between the cyanoacrylamide warhead and Cys199, which could help in the development of more potent covalent inhibitors of GSK-3 beta. Preliminary studies on in vitro models of Parkinson’s disease revealed that compound 12 is not cytotoxic and shows neuroprotective activity. These results encourage further investigations to validate GSK-3 beta/CK-1 delta inhibition as a possible new strategy to treat neuroinflammatory/degenerative diseases.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. HPLC of Formula: C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Microwave Assisted Three Component One-pot Synthesis of Bis(aminoazolo[1,5-a]pyrimidines) and Bis(aminoazino[1,2-a]benzimidazoles) Bearing Thiazole Moiety WOS:000491263700031 published article about DIHYDROOROTATE DEHYDROGENASE; ANTIMICROBIAL EVALUATION; BIOLOGICAL EVALUATION; BRIDGEHEAD NITROGEN; SMALL-MOLECULE; DERIVATIVES; DISCOVERY; DESIGN; BENZOTHIAZOLE; BENZIMIDAZOLE in [Mekky, Ahmed E. M.; Sanad, Sherif M. H.; Ahmed, Ahmed A. M.] Cairo Univ, Chem Dept, Fac Sci, Giza 12613, Egypt; [Ahmed, Ahmed A. M.] Jouf Univ, Sakaka, Saudi Arabia in 2019.0, Cited 55.0. SDS of cas: 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Novel bis[(thiazol-2-yl)acetonitrile] derivatives were prepared in good yields by the cyclocondensation of bis(bromoacetyl) derivatives with two equivalents of 2-cyanothioacetamide in dioxane at reflux. The bis[(thiazol-2-yl)acetonitrile] derivatives were taken as synthetic precursors for the synthesis of novel bis(aminoazolo[1,5-a]pyrimidines), bearing thiazole moiety. The target molecules were prepared by the three component one pot reaction of bis[(thiazol-2-yl)acetonitrile] derivatives, dimethylformamide-dimethylacetal and several of 3-aminopyrazoles in pyridine under microwave irradiation at 140 degrees C for 2 h. Using the same protocol, novel bis(aminotriazolo[1,5-a]pyrimidines), bis(aminopyrimido[1,2-a]benzimidazoles) and bis(aminopyrido [1,2-a]benzimidazoles), incorporating thiazole moieties, were prepared by using the appropriate heterocyclic amine or 2-(1H-benzoimidazol-2-yl)acetonitrile instead of 3-aminopyrazoles. The structure of the newly prepared thiazoles was confirmed via considering their elemental analyses and spectral data.

Welcome to talk about 61-82-5, If you have any questions, you can contact Mekky, AEM; Sanad, SMH; Ahmed, AAM or send Email.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Synthesis, chemical and biological investigations of new Ru(III) and Se(IV) complexes containing 1,3,5-triazine chelating derivatives published in 2019.0. Application In Synthesis of 1H-1,2,4-Triazol-5-amine, Reprint Addresses Al-Khodir, FAI (corresponding author), Princess Nourah Bint Abdulrahman Univ, Coll Sci, Dept Chem, Riyadh, Saudi Arabia.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

A series of vital complexes of [Se (L-n) (Cl)(x)]center dot yCl (where n = L-1, L-2, L-3 and L-4; x = 1, 2, or 3 and y = 1, 2, or 3) and [Ru (L-n) (Cl)(x) (H2O)(y)]zCl (where x = 2 or 3; y = 0,1 or 2 and z = 0 or 1) have been synthesized from the chemical reactions between ruthenium (III) or selenium (IV) salts and tri-substituted s-triazine derivatives (L-1 = N-2-(4-chlorophenyl)-N-4,N-6-di (pyrimidin-2-yl)-1,3,5-triazine-2,4,6-triamine; L-2 = N-2-(4-chlorophenyl)-N-4- (pyrimidin-2-yl)- N-6-(thiazol-2-yl)-1,3,5-triazine-2,4,6-triamine; L-3 = 6-chloro-N-2-(pyrimidin-2-yl)-N-4-(1H-1,2,4-triazol-3-yl)-1,3,5-triazine-2,4-diamine and L-4 = 6-chloro-N-2-(4-chlorophenyl)-N-4-(pyrimidin-2-yl)-1,3,5-triazine-2,4-diamine). The structural was investigated using of elemental analyses, molar conductance, IR, UV-Vis, magnetic susceptibility, H-1, C-13 NMR spectra and thermal analyses. The surface morphology behaviors of selenium (IV) and ruthenium (111) complexes were studied based on scanning and transmittance electron microscopes. The crystalline nature of s-triazine complexes have been investigated using X-ray powder diffraction spectra. Spectral results were concluded that the ligand acts as a neutral bidentate for (L-1 and L-4) and tridentate for (L-2 and L-3), and coordinates through the nitrogen atom of triazine ring and nitrogen atoms of (pyrimidine, thiazole, and triazole) rings towards metal ion. The cytotoxic IC50 results of the free L-n ligands and its selenium (IV) complexes in vitro against the human colon and lung cancer cell lines introduced a promising efficiency. (C) 2018 Elsevier B.V. All rights reserved.

Welcome to talk about 61-82-5, If you have any questions, you can contact Al-Khodir, FAI; Al-Warhi, T; Abumelha, HMA; Al-Issa, SA or send Email.. Application In Synthesis of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics