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An article Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase WOS:000552629800008 published article about GROWTH-FACTOR RECEPTOR-2; BIOLOGICAL EVALUATION; ANTICANCER EVALUATION; INHIBITORS; ANGIOGENESIS; RESISTANCE; MECHANISM; DISCOVERY; DESIGN in [Dawood, Dina H.] Natl Res Ctr, Chem Nat & Microbial Prod Dept, Pharmaceut & Drug Ind Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt; [Nossier, Eman S.] Al Azhar Univ, Fac Pharm Girls, Dept Pharmaceut Chem, POB 11754, Cairo, Egypt; [Ali, Mamdouh M.; Mahmoud, Abeer E.] Natl Res Ctr, Biochem Dept, Genet Engn & Biotechnol Res Div, 33 El Bohouth St,POB 12622, Giza, Egypt in 2020.0, Cited 50.0. Safety of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Based on the previous studies that revealed the valuable role of pyrazole scaffold in cancer management and VEGFR-2 inhibition, a new set of pyrazole conjugated with pyrazoline, triazolopyrimidine and pyrazolone moieties were synthesized and investigated for their anticancer efficiency against human breast cancer MCF-7. The anticancer screening revealed the significant sensitivity of breast carcinoma towards compounds 4b, 5c, 6c, 7b, 7c and 12c with IC50 values ranging from 16.50 – 26.73 mu M in comparison with tamoxifen (IC50 = 23.31 mu M). Moreover, the new analogues were further examined for their VEGFR-2 inhibitory activity, among the tested derivatives 5c, 6c, 7b, 7c and 12c displayed prominent inhibitory efficiency versus VEGFR-2 kinase with % inhibition ranging from 70 to 79%. Compounds 6c, 7c and 12c revealed inhibitory efficiency in nanomolar level with IC50 (913.51, 225.17 and 828.23 nM, respectively) comparing to sorafenib (IC50 = 186.54 nM). Flow cytometric analysis revealed that the promising compound 12c prompted pre-G1 apoptosis and cell growth cessation at G2/M phase and stimulated apoptosis via activation of caspase-3. Moreover, molecular docking study of the promising derivatives was performed to highlight their binding modes and interactions with the amino acid residues of VEGFR-2 enzyme.

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Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Kovygin, YA; Vandyshev, DY; Ledenyova, IV; Kosheleva, EA; Polikarchuk, VA; Kozaderov, OA; Shikhaliev, KS or concate me.

Formula: C2H4N4. Authors Kovygin, YA; Vandyshev, DY; Ledenyova, IV; Kosheleva, EA; Polikarchuk, VA; Kozaderov, OA; Shikhaliev, KS in SPRINGER published article about in [Kovygin, Yu A.; Vandyshev, D. Yu; Ledenyova, I., V; Kosheleva, E. A.; Polikarchuk, V. A.; Kozaderov, O. A.; Shikhaliev, Kh S.] Voronezh State Univ, 1 Univ Skaya Pl, Voronezh 394018, Russia in 2021.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A convenient method for the synthesis of 2-(2-R-5-oxo-6,7-dihydro-4H-[1,2,4]triazolo-[1,5-a]pyrimidin-6-yl)acetanilides based on the regioselective domino reaction of N-arylitaconimides with substituted 3-aminotriazoles was proposed. Presumably, the reaction pathway includes the conjugated aza-addition of the endo-nucleophilic center of triazole to imide, followed by the recyclization of the intermediate to triazolo[1,5-a]pyrimidine.

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Kovygin, YA; Vandyshev, DY; Ledenyova, IV; Kosheleva, EA; Polikarchuk, VA; Kozaderov, OA; Shikhaliev, KS or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Welcome to talk about 61-82-5, If you have any questions, you can contact Nayak, A; Smetana, V; Mudring, AV; Rogers, RD or send Email.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

An article Anhydrous vs Hydrated f-Element Acetate Polymers Dictated by the Stoichiometry of Protic Acidic/Basic Azole Mixtures WOS:000639012100064 published article about CRYSTAL-STRUCTURE; ACTINIDE; LANTHANIDE; SEPARATION; CHEMISTRY; COVALENCY; LIGAND in [Nayak, Amrita; Rogers, Robin D.] Univ Alabama, Coll Arts & Sci, Tuscaloosa, AL 35487 USA; [Smetana, Volodymyr; Mudring, Anja-Verena; Rogers, Robin D.] Stockholm Univ, Dept Mat & Environm Chem, S-10691 Stockholm, Sweden in 2021.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Continuing our investigations of ionic liquid (IL) based routes to a library of f-element/soft donor complexes which could be studied crystallographically, we have explored the dissolution of f-element salts in protic imidazole-based ILs containing only soft donors at high temperatures to drive off volatiles, including water and carboxylic or mineral acids. Here we present our results, reacting acidic and basic azoles in 1:3 or 1:1 stoichiometric compositions at elevated temperature, followed by saturation with Nd(OAc)(3)center dot xH(2)O or Ce(OAc)(3)center dot xH(2)O, which led to 13 new metal-acetate polymeric complexes identified by single-crystal X-ray diffraction. We found that the diversity in coordination modes of the simple acetate ligand that interfere with substitution of the softer N donors led to several readily crystallizable complexes forming two distinct groups with respect to f-element interaction with the ionic liquid precursors. When the acidic/basic azole ratio was 1:3, acetate and a neutral basic azole were found to be coordinated to the metal centers but no water, although in one case (2) water was observed in the secondary coordination sphere: [Ce(mu(2)-OAc)(3)(C(1)im)](n) (1, C(1)im = 1-methylimidazole), [Nd(mu(2)-(OAc)(3)(C(1)im)](n)center dot nH(2)O (2), [Ce(mu(2)-OAc)(3)(C(2)im)](n) (3, C(2)im = 1-ethylimidazole), [Ln(mu(2)-OAc)(3)DMF](n) (Ln = Nd (4), Ce (5); dimethylformamide (DMF) was substituted for the azole mixture), and [Nd(mu(2)-OAc)(3)(C(4)im)](n) (6, C(4)im = 1-butylimidazole). However, when the stoichiometric ratio was 1:1, water was always observed coordinated to the metal ions with the acidic azole included in the structure as a solvate or cocrystal, despite a higher reaction temperature: [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(1,2,3-Taz) (7,1,2,3-Taz = 1,2,3-triazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(4,5-DCim) (Ln = Nd (8), Ce (9), 4,5-DCim = 4,5-dicyanoimidazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(3,5-diNH(2)-1,2,4-Taz) (Ln = Nd (10), Ce (11), 3,5diNH(2)-1,2,4-Taz = 3,5-diamino-1,2,4-triazole), [Ce(mu(2)-OAc)(3)(OH2)](n)center dot n(3-NH2-1,2,4-Taz) (12, 3-NH2-1,2,4-Taz = 3-amino-1,2,4-triazole), and [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(5-NH2-Tz) (13, 5-NH2-Tz = 5-aminotetrazole). All of the compounds retain the Ln:OAc- ratio of 1:3 and form 1D polymeric chains; however, they exhibit a variety of coordination modes affecting the degree of chain condensation. The isolation of both hydrated and anhydrous products revealed different abilities of the investigated soft N-donors to compete with O-donors finding their place in the coordination sphere of the lanthanide or in the crystal lattice.

Welcome to talk about 61-82-5, If you have any questions, you can contact Nayak, A; Smetana, V; Mudring, AV; Rogers, RD or send Email.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Recommanded Product: 61-82-5. In 2021.0 J POROUS MAT published article about METAL-ORGANIC FRAMEWORK; HIGH-PERFORMANCE; ASSISTED SYNTHESIS; ACTIVATED CARBON; ENERGY-STORAGE; SUPERCAPACITORS; GRAPHENE; LAYER in [Zhang, Chi; Yang, Jing; Zhang, Jianqiang; Zhao, Xia; Feng, Huixia; Luo, Heming] Lanzhou Univ Technol, Sch Petrochem Engn, Lanzhou, Peoples R China in 2021.0, Cited 39.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Metal-organic framework compounds with abundant network structures are widely used in gas separation and storage, non-linear optics, catalysis, functional materials, and other applications. Here, self-doped nitrogen porous carbon was prepared by a one-step carbonization of Zn-2(ATRZ)(2)SO4 center dot 3H(2)O synthesized using a hydrothermal method. The self-doped nitrogen porous carbon material (ZYC-800) features a three-dimensional network structure, high specific surface area of 725 m(2) g(-1), and high nitrogen (7.26%) and oxygen (5.46%) contents. Consequently, the ZYC-800 electrode shows a high specific capacitance of 205.5 F g(-1)at a current density of 1.0 A g(-1)and high capacitance retention rate of 71.1% after 5000 cycles. Moreover, a composite electrode material (ZYC-800-5.3) with small redox additives was prepared and showed a high specific capacitance of 274.1 F g(-1)at a current density of 1.0 A g(-1). After 5000 cycles, the capacitance retention rate is 72.8%. The results show that the addition of redox additives in self-doped nitrogen porous carbon is an effective method in the development of high performance supercapacitors.

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Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Why Are Children Getting Addicted To C2H4N4

Welcome to talk about 61-82-5, If you have any questions, you can contact Mabkhot, YN; Algarni, H; Alsayari, A; Bin Muhsinah, A; Kheder, NA; Almarhoon, ZM; Al-aizari, FA or send Email.. Category: Triazoles

Mabkhot, YN; Algarni, H; Alsayari, A; Bin Muhsinah, A; Kheder, NA; Almarhoon, ZM; Al-aizari, FA in [Mabkhot, Yahia N.] King Khalid Univ, Coll Pharm, Dept Pharmaceut Chem, Abha 61441, Saudi Arabia; [Algarni, H.] King Khalid Univ, Dept Phys, Fac Sci, POB 9004, Abha 61441, Saudi Arabia; [Algarni, H.] King Khalid Univ, RCAMS, POB 9004, Abha 61441, Saudi Arabia; [Alsayari, Abdulrhman; Bin Muhsinah, Abdullatif] King Khalid Univ, Coll Pharm, Dept Pharmacognosy, Abha 61441, Saudi Arabia; [Kheder, Nabila A.] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt; [Almarhoon, Zainab M.; Al-aizari, Faiz A.] King Saud Univ, Coll Sci, Dept Chem, POB 2455, Riyadh 11451, Saudi Arabia; [Al-aizari, Faiz A.] AL Baydha Univ, Fac Sci, Dept Chem, Albaydah 38018, Yemen published Synthesis, X-ray Analysis, Biological Evaluation and Molecular Docking Study of New Thiazoline Derivatives in 2019.0, Cited 58.0. Category: Triazoles. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

A series of new thiazoline derivatives were synthesized. Structure analyses were accomplished employing H-1-NMR, C-13-NMR, X-ray and MS techniques. The in vitro antitumor activities were assessed against human hepatocellular carcinoma (HepG-2) and colorectal carcinoma (HCT-116) cell lines. The results revealed that the thiazolines 5b and 2c exhibited significant activity against the two cell lines. The in vitro antimicrobial screening showed that the thiazolines 2c, 5b and 5d showed promising inhibition activity against Salmonella sp. Additionally, the inhibition activity of thiazolines 2e and 5b against Escherichia coli was comparable to that of the reference compound gentamycin.

Welcome to talk about 61-82-5, If you have any questions, you can contact Mabkhot, YN; Algarni, H; Alsayari, A; Bin Muhsinah, A; Kheder, NA; Almarhoon, ZM; Al-aizari, FA or send Email.. Category: Triazoles

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Mohlala, RL; Coyanis, EM; Fernandes, MA; Bode, ML or concate me.

Authors Mohlala, RL; Coyanis, EM; Fernandes, MA; Bode, ML in PERGAMON-ELSEVIER SCIENCE LTD published article about MULTICOMPONENT REACTIONS; HETEROCYCLIC-SYSTEMS; CONSTRUCTION; UGI; ADDITIONS; ANALOGS; AMINES in [Mohlala, Reagan L.; Coyanis, E. Mabel] MINTEK, Adv Mat Div, Private Bag X3015, ZA-2125 Randburg, South Africa; [Mohlala, Reagan L.; Fernandes, Manuel A.; Bode, Moira L.] Univ Witwatersrand, Sch Chem, Mol Sci Inst, PO Wits, ZA-2050 Johannesburg, South Africa in 2020.0, Cited 60.0. Formula: C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A one-pot reaction of the zwitterion formed from an isocyanide and an acetylenedicarboxylate with different five-membered rings containing both an acidic proton and a suitable nucleophile resulted in the preparation of novel 5-membered ring fused pyrimidine derivatives in yields ranging from 18 to 87%. (C) 2020 Elsevier Ltd. All rights reserved.

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Mohlala, RL; Coyanis, EM; Fernandes, MA; Bode, ML or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Recommanded Product: 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact McCune, F; Samson-Robert, O; Rondeau, S; Chagnon, M; Fournier, V or send Email.

In 2021.0 ENVIRON SCI POLLUT R published article about APIS-MELLIFERA; NEONICOTINOID INSECTICIDES; ENVIRONMENTAL RISKS; WARDECKER WATERERS; WATERING DEVICE; SURFACE WATERS; HYMENOPTERA; RESIDUES; WORKERS; APIDAE in [McCune, Frederic; Samson-Robert, Olivier; Rondeau, Sabrina; Fournier, Valerie] Univ Laval, Ctr Rech & Innovat Vegetaux, Quebec City, PQ G1V 0A6, Canada; [Rondeau, Sabrina] Univ Guelph, Sch Environm Sci, Guelph, ON N1G 2W1, Canada; [Chagnon, Madeleine] Univ Quebec Montreal, Dept Sci Biol, Montreal, PQ H3C 3P8, Canada in 2021.0, Cited 104.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Water is essential for honey bees (Apis mellifera L.), but contaminated sources of water in agricultural environments represent a risk of exposure to potentially harmful contaminants. Providing clean water to honey bees could be an efficient and cost-effective measure for beekeepers to reduce bee mortality associated with pesticides and improve the health of their colonies. The main goal of this study was to design a waterer prototype to fulfill the water requirements of honey bees and to evaluate the potential of this waterer in improving colonies’ health in agricultural settings, through mitigating the possible impact of an exposure to pesticides from puddle water. We tested the preference of honey bees regarding water composition and waterer prototypes, among which honey bees showed a strong preference for salted water and a poultry-type waterer. Our waterer models were quickly adopted and intensively used through the season in both the context of honey production in field crops and pollination services in cranberry crops. However, in neither context did the use of waterers reduce worker mortality nor increase overall colony weight. Our waterers provided bees with water containing fewer pesticides and were associated with reduced risks of drowning compared to natural sources of water. Our study suggests that the use of waterers fulfills an important requirement for honey bees and represents an interesting and convenient precautionary measure for beekeepers.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. Welcome to talk about 61-82-5, If you have any questions, you can contact McCune, F; Samson-Robert, O; Rondeau, S; Chagnon, M; Fournier, V or send Email.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Silva, EN; Silveira, JAG; Aragao, RM; Vieira, CF; Carvalho, FEL or concate me.. SDS of cas: 61-82-5

SDS of cas: 61-82-5. Silva, EN; Silveira, JAG; Aragao, RM; Vieira, CF; Carvalho, FEL in [Silva, Evandro Nascimento] Univ Estadual Ceara, Fac Educ Ciencias & Letras Sertao Cent, BR-63900000 Quixada, Ceara, Brazil; [Silveira, Joaquim A. G.; Vieira, Cinthya F.; Carvalho, Fabricio E. L.] Univ Fed Ceara, Dept Bioquim & Biol Mol, Lab Metab Plantas, Campus Pici,CP 6020, BR-60451970 Fortaleza, Ceara, Brazil; [Aragao, Rafael M.] UFRA, Campus Capanema, BR-68700030 Capanema, Para, Brazil published Photosynthesis impairment and oxidative stress in Jatropha curcas exposed to drought are partially dependent on decreased catalase activity in 2019.0, Cited 58.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Catalase (CAT) is a crucial enzyme to control the excess peroxisomal H2O2 produced during photorespiration. In many plant species, this enzymatic activity decreases in response to drought but its specific role in photosynthesis and redox metabolism is still poorly understood. In this study was tested the hypothesis that photosynthetic and oxidative changes induced by drought are dependent on CAT activity. For this, Jatropha curcas, a drought-tolerant species, was subjected to water deficit and CAT inhibition by a specific pharmacological inhibitor (3-AT), in order to decrease the activity of this enzyme to a similar level as compared to that exhibited by water deficit-treated plants. The CO2 assimilation and other photosynthetic-related parameters were decreased more intensively by drought as compared to plants exposed to 3-AT, whereas the photochemical efficiency of PSII remained unchanged in both conditions. Non-photochemical quenching was strongly increased in drought-treated plants, but only slightly increased in 3-AT treatment. Membrane integrity and lipid peroxidation were strongly increased in both treatments, while H2O2 content was increased only by drought imposition. Ascorbate peroxidase and superoxide dismutase activities were increased in both drought and 3-AT treatments, but glycolate oxidase was strongly increased only in drought-stressed plants. The obtained results evidence that CO2 assimilation and oxidative protection in leaves of Jatropha curcas plants exposed to water deficit are greatly dependent on drought-induced CAT activity deficiency.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Silva, EN; Silveira, JAG; Aragao, RM; Vieira, CF; Carvalho, FEL or concate me.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Welcome to talk about 61-82-5, If you have any questions, you can contact Zhang, QM; Li, D; Cao, XK; Gu, HX; Deng, W or send Email.. SDS of cas: 61-82-5

An article Self-Assembled Microgels Arrays for Electrostatic Concentration and Surface-Enhanced Raman Spectroscopy Detection of Charged Pesticides in Seawater WOS:000484644800039 published article about SERS DETECTION; NANOPARTICLES; POINT; PRECONCENTRATION; MOLECULES; FILMS in [Zhang, Qinmei; Li, Dan; Cao, Xiukai; Deng, Wei] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China; [Gu, Haixin] Shanghai Fire Res Inst MEM, 918 Minjing Rd, Shanghai 200438, Peoples R China in 2019.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. SDS of cas: 61-82-5

Development of flexible surface-enhanced Raman spectroscopy (SERS) substrate with controllable hot spots has spurred increasing interest because of its unique structure and plasmonic properties. Here, charged poly(vinyl alcohol) microgels containing silver nanoparticles are developed by using microfluidic emulsification to produce a smart SERS sensor with charge screening and signals amplification. Importantly, this charged microgel enables the selective concentration of counter-charged molecules and induces the formation of assembled arrays at an immiscible liquid-liquid interface because of the electrostatic interaction. The SERS-active microgels arrays possess controllable structures and facilitate on-site determination of charged pesticides with an enhancement factor of 5.0 x 10(5). Such nanostructures present the ease of assembly, stability, and reproducibility which allow multiplex detection of analytes at aqueous and organic phases without any pretreatment of complex matrix samples. The interfacial sensing platform for on-site SERS analysis of charged pesticides will open vast possibilities for a wide range of in-field applications.

Welcome to talk about 61-82-5, If you have any questions, you can contact Zhang, QM; Li, D; Cao, XK; Gu, HX; Deng, W or send Email.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

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Product Details of 61-82-5. Kolodziej, B; Morawiak, M; Schilf, W; Kamienski, B in [Kolodziej, Beata] West Pomeranian Univ Technol, Fac Chem Technol & Engn, Dept Inorgan & Analyt Chem, Al Piastow 42, PL-71065 Szczecin, Poland; [Morawiak, Maja; Schilf, Wojciech; Kamienski, Bohdan] Polish Acad Sci, Inst Organ Chem, Ul Kasprzaka 44-52, PL-01224 Warsaw, Poland; [Kamienski, Bohdan] Polish Acad Sci, Inst Phys Chem, Ul Kasprzaka 44-52, PL-01224 Warsaw, Poland published Structure investigations of Schiff bases derived from 3-amino-1H-1,2,4-triazole in 2019.0, Cited 62.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In the present paper, twelve Schiff bases derived from 3-amino-1H-1,2,4-triazole (ATz) and various benzaldehydes, and salicylaldehydes were synthesized. The H-1, C-13, and N-15 NMR data are discussed in relation to the structure of ATz and its imine products. In addition, X-ray, ATR-FTIR, and UV-Vis analytical techniques are used for structure elucidation of ATz-based Schiff bases. It was found that the starting material, 3-amino-1H-1,2,4-triazole, exists as tautomeric mixture of three forms (Graphical Abstract) in solution, whereas in the solid state (C-13 and N-15 CPMAS data) potentially tautomeric proton is located on nitrogen atom traditionally marked as N-2 (Graphical Abstract, 2N-H structure). All investigated Schiff bases derived from salicylaldehydes exist in both phases as tautomeric equilibrium mixtures, where enol-imine forms are dominated structures. The positions of those equilibria only very slightly depend on substituents in phenol ring. Generally, the contributions of keto-amine forms in the solid state are higher comparing with DMSO solutions. (C) 2019 Published by Elsevier B.V.

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Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics