Tag: 100-200

On November 7, 2014, Quan, Xue-Jing; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui published an article.Safety of 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was p-Toluenesulfonic Acid Mediated 1,3-Dipolar Cycloaddition of Nitroolefins with NaN3 for Synthesis of 4-Aryl-NH-1,2,3-triazoles. And the article contained the following:

A p-TsOH-mediated 1,3-dipolar cycloaddition of nitroolefins and sodium azide for the synthesis of 4-aryl-NH-1,2,3-triazoles has been developed. p-TsOH was discovered as a vital additive in this type of 1,3-dipolar cycloaddition This novel cycloaddition reaction is a good method for the rapid synthesis of valuable 4-aryl-NH-1,2,3-triazoles in high yields. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Safety of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to aryltriazole preparation toluenesulfonic acid mediated dipolar cycloaddition, dipolar cycloaddition nitroolefin sodium azide aryltriazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Safety of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On December 1, 2017, Kang, Taewon; Kim, Hongsik; Lee, Dongwhan published an article.Application In Synthesis of 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was Triazoliptycenes: A Twist on Iptycene Chemistry for Regioselective Cross-Coupling To Build Nonstacking Fluorophores. And the article contained the following:

Triazoliptycene fluorophores have been designed and synthesized, in which a three-dimensional propeller-like iptycene motif is employed to suppress intermol. π-π stacking in the solid state. Key to the success of this modular synthesis is a stereoelectronic bias imposed by the iptycene scaffold, which assists the desired regioselectivity in the C-N cross-coupling step as the last-stage structure diversification from a common precursor. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Application In Synthesis of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to crystal mol structure triazoliptycene fluorophore, triazoliptycene modular preparation regioselective coupling nonstacking fluorophore, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application In Synthesis of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On April 20, 2018, Lee, Heejin; Lee, Jae Kyun; Min, Sun-Joon; Seo, Hyeonglim; Lee, Youngbok; Rhee, Hakjune published an article.HPLC of Formula: 5301-96-2 The title of the article was Copper(I)-Catalyzed Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Azidoformates and Aryl Terminal Alkynes. And the article contained the following:

The copper(I)-catalyzed azide-alkyne cycloaddition reaction has been extensively studied and widely applied in organic synthesis. However, the formation of 1,2,3-triazoles with electron-deficient azide has been a challenging problem. In this report, we have demonstrated the formation of regioselective 1,4-disubstituted 1,2,3-triazoles from various types of aryl terminal alkynes and azidoformates, which are electron-deficient azides, using a commercialized [Cu(CH3CN)4]PF6 copper(I) catalyst under mild conditions. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).HPLC of Formula: 5301-96-2

The Article related to triazole regioselective preparation cycloaddition azidoformate aryl terminal alkyne, azide alkyne cycloaddition azidoformate aryl terminal alkyne, crystal structure phenyl triazole carboxylate and other aspects.HPLC of Formula: 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Bagheri, Sepideh; Nejad, Masoumeh Jadidi; Pazoki, Farzane; Miraki, Maryam Kazemi; Heydari, Akbar published an article in 2019, the title of the article was Folic-Acid-Functionalized Magnetic Nanoparticles as Green and Magnetic Recyclable Catalyst for the Synthesis of 4-Aryl-NH-1,2,3-triazoles in a Green Media.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

A useful, robust, and cheap procedure was obtained for the synthesis of 4-aryl-NH-1,2,3-triazoles via aromatic aldehydes, nitromethane and choline azide in the presence of folic acid immobilized magnetic nanoparticle with good yields. The magnetic catalyst was easily synthesized and can be recycled at least five times with no significant loss in activity. In addition, the choline azide was used as a reagent and green solvent. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to reusable folic acid functionalize iron oxide catalyst preparation property, aromatic aldehyde nitromethane choline azide iron oxide catalyst cycloaddition, aryltriazole preparation green chem and other aspects.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On April 17, 2003, Kallander, Lara S.; Ryan, Dominic M.; Thompson, Scott K. published a patent.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole The title of the patent was Preparation of 4-phenyl-1H-1,2,3-triazoles as inhibitors of type 2 methionine aminopeptidase (MetAP2). And the patent contained the following:

The title compounds [I; X, Y = N, CH, CR, provided that X and Y are not both CR; R = H, halo, alkyl, etc.; R1 = H, halo, alkyl, etc.; R2, R3 = H, halo, alkyl, etc.] which are non-peptide, reversible inhibitors of type 2 methionine aminopeptidase, and useful in treating conditions mediated by angiogenesis, such as cancer, hemangioma, proliferative retinopathy, rheumatoid arthritis, atherosclerotic neovascularization, psoriasis, ocular neovascularization and obesity, were prepared Thus, reacting 3-ethynylphenylamine with Et glyoxalate in the presence of NaBH(OAc)3 and AcOH in 1,2-dichloroethane followed by treating the resulting ethoxycarbonylmethyl-(3-ethynylphenyl)amine with trimethylsilylazide in PhMe afforded I [X, Y = CH; R1, R2 = H; R3 = NHCH2CO2Et]. The compounds I show MetAP2 inhibitor activity having IC50 values in the range of 0.0001 to 100 μM. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to phenyltriazole preparation methionine aminopeptidase metap2 inhibitor angiogenesis antitumor, triazole phenyl preparation methionine aminopeptidase metap2 inhibitor angiogenesis antitumor and other aspects.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Mirzaei-Mosbat, Maryam; Ghorbani-Vaghei, Ramin; Sarmast, Narges published an article in 2019, the title of the article was One-pot synthesis of 4-aryl-NH-1,2,3-triazoles in presence of Fe3O4@SiO2@propyl-HMTA as a new basic catalyst.Formula: C9H9N3 And the article contains the following content:

Hexamethylenetetramine-functionalized magnetic Fe3O4 nanoparticles (Fe3O4@SiO2@Propyl-HMTA) catalyst was prepared and characterized by FT-IR, SEM, TEM, TGA, XRD and VSM. This nanomagnetic catalyst had several advantages such as easier separation, recycling from reaction media due to its heterogeneous nature, higher reactivity and catalytic power due to its enhanced surface area. Further, this catalyst was utilized for the synthesis of 4-aryl-NH-1,2,3-triazole derivs I [Ar = 4-ClC6H4, 2-O2NC6H4, 3-indolyl, etc.] by three-component reaction of aldehydes, nitromethane and sodium azide through Henry condensation and then in situ [3+2] cycloaddition reaction. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Formula: C9H9N3

The Article related to hmta functionalized silica coated iron oxide nanoparticle catalyst preparation, triazole green preparation, aldehyde nitromethane sodium azide henry cycloaddition iron oxide nanocatalyst and other aspects.Formula: C9H9N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On July 12, 2017, Vergara-Arenas, Blanca Ivonne; Lomas-Romero, Leticia; Angeles-Beltran, Deyanira; Negron-Silva, Guillermo Enrique; Gutierrez-Carrillo, Atilano; Lara, Victor Hugo; Morales-Serna, Jose Antonio published an article.Electric Literature of 5301-96-2 The title of the article was Multicomponent synthesis of 4-aryl-NH-1,2,3-triazoles in the presence of Al-MCM-41 and sulfated zirconia. And the article contained the following:

The acid properties of Al-MCM-41 and sulfated zirconia were used to develop a strategy for the synthesis of 4-aryl-NH-1,2,3-triazoles via a multicomponent reaction involving various benzaldehydes, sodium azide and nitromethane. The efficiency of the process is analyzed from the perspective of the difference in acids among the catalysts used. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Electric Literature of 5301-96-2

The Article related to triazole preparation, aldehyde nitromethane sodium azide multicomponent condensation aluminosilicate sulfonated zirconia, mcm 41 aluminosilicate sulfonated zirconia catalyst preparation and other aspects.Electric Literature of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zhang, You-Can; Jin, Rui; Li, Luo-Yuan; Chen, Zili; Fu, Li-Min published an article in 2017, the title of the article was Study on the Fluorescent activity of N2-indolyl-1,2,3-triazoles.COA of Formula: C9H9N3 And the article contains the following content:

A new type of blue emitter, N2-indolyl-1,2,3-triazoles (NITs), with the λmax ranging from 420-480 nm and Stokes shift from 89-143 nm, were synthesized through the coupling reaction of indoles with triazole derivatives The influence of different substitution patterns on the optical properties (efficiency, excitation, and emission wavelengths) of the NITs was investigated. In addition, one palladium complex was synthesized by using NITs as the ligands, which, however, exhibited no fluorescent activity, but did show the enhanced co-planarity. Lastly, two bio-active mol. derivatives were explored for the potential use of these novel dyes in related chem. and biol. applications. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).COA of Formula: C9H9N3

The Article related to indolyl triazole preparation fluorescence, triazole indole coupling, n2-aryl-1,2,3-triazoles (nats), n2-indolyl-1,2,3-triazoles (nits), blue-emissive fluorophore, fluorescent activity and other aspects.COA of Formula: C9H9N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On March 18, 2022, Motornov, Vladimir; Beier, Petr published an article.Formula: C9H9N3 The title of the article was Access to Fluoroalkylated Azoles and 2-Acylaminoketones via Fluorinated Anhydride-Mediated Cleavage of NH-1,2,3-Triazoles. And the article contained the following:

NH-1,2,3-Triazoles I (R = Ph, 2-chlorophenyl, cyclohex-1-enyl, etc.; R1 = H, CH3, C2H5, C6H5, (CH2)2C(O)2CH3, Cl) undergo a ring cleavage in reactions with fluorinated acid anhydrides (trifluoroacetic, trichloroacetic, difluoroacetic, chlorodifluoroacetic and pentafluoropropionic anhydrides) by nitrogen acylation and acid-mediated triazole ring opening. Structurally diverse fluoroalkylated oxazoles II (X = H, F, Cl, CF3) were prepared from 4,5-disubstituted-1,2,3-triazoles I. Efficient synthesis of 2-acylaminoketones RC(O)CH2NHC(O)CF2X and 2,2,2-trichloro-N-(2-oxo-2-(p-tolyl)ethyl)acetamide was achieved from 4-substituted-1,2,3-triazoles I (R1 = H). Finally, easy access to fluoroalkylated imidazoles III (R2 = 4-methylphenyl, 4-chlorophenyl, 4-methoxyphenyl; R3 = Me, n-Bu; R4 = CF3, CF2CF3) and 1,2,4-triazines IV was developed by a one-pot two step route from NH-triazoles, fluorinated anhydrides and amines such as methanamine and butanamine or hydrazine, resp. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Formula: C9H9N3

The Article related to fluoroalkyl oxazole preparation, acylaminoketone preparation, imidazole fluoroalkyl preparation, trifluoromethyl triazine preparation, triazole acid anhydride acylation ring opening and other aspects.Formula: C9H9N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Payra, Soumen; Saha, Arijit; Banerjee, Subhash published an article in 2018, the title of the article was On Water Cu@g-C3N4 Catalyzed Synthesis of NH-1,2,3-Triazoles via [2+3] Cycloadditions of Nitroolefins/Alkynes and Sodium Azide.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

Here, graphitic polymeric carbon nitride supported copper chloride (Cu@g-C3N4) was prepared by the calcination of urea followed by immobilization of CuCl2 and characterized by powder X-ray diffraction, field emission SEM, high resolution transmission electron microscopy, XPS studies. An efficient and regioselective protocol for the on water synthesis of 4-aryl-NH-1,2,3-triazole derivatives I (R1 = H, 4-OMe, 2-NO2, etc.) via 1,3-dipolar cycloaddition reactions of nitroolefins/phenylacetylenes to sodium azide were demonstrated by using Cu@g-C3N4 as robust and reusable catalyst. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to aryl triazole preparation regioselective, nitroolefin phenylacetylene sodium azide dipolar cycloaddition, graphitic carbon nitride supported copper chloride preparation catalyst and other aspects.Recommanded Product: 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics