Tag: 100-200

Luo, Guoli; Sun, Chenyang; Li, Yan; Li, Xiaoxiao; Zhao, Zhigang published an article in 2018, the title of the article was N2-selective alkylation of NH-1,2,3-triazoles with vinyl ethers via gold catalysis.Computed Properties of 5301-96-2 And the article contains the following content:

A new method was developed to synthesize N2-alkyl-substituted 1,2,3-triazoles via gold catalyzed alkylation of vinyl ethers with mono- and unsubstituted NH-1,2,3-triazoles and benzotriazole. A hydrogen bond between the oxygen atom of the vinyl ethers, activated via the gold catalyst, and the NH-1,2,3-triazoles was supposed to be generated, which selectively gave the N2-alkylation products. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Computed Properties of 5301-96-2

The Article related to alkyltriazole preparation, triazole vinyl ether gold catalyst regioselective alkylation, Heterocyclic Compounds (More Than One Hetero Atom): Triazines and other aspects.Computed Properties of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Wang, Liang; Pan, Liang; Chen, Qun; He, Mingyang published an article in 2017, the title of the article was Acidic ion-exchange resin-catalyzed synthesis of 4-aryl-1H-1,2,3-triazoles.Related Products of 5301-96-2 And the article contains the following content:

A series of 4-aryl-1H-1,2,3-triazole derivatives (I, Ar = Ph, 4-methylphenyl, 4-methoxyphenyl, etc.) were synthesized by 1,3-dipolar cycloaddition of nitroolefins with NaN3 using Amberlite IR-120 resin as the catalyst. Compared with conventional methods, good efficiency, mild reaction conditions and good substrate compatibility are the major advantages of the present protocol. In addition, the catalyst can be easily recovered by filtration, and can be reused for successive six runs with slight decrease in its activity. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Related Products of 5301-96-2

The Article related to acidic ion exchange resin aryl triazole, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Related Products of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On September 11, 2013, Kuang, Chunxiang; Yang, Qing; Lixin, Juanzi; Wang, Xun; Li, Yonggang published a patent.Electric Literature of 5301-96-2 The title of the patent was Method for synthesizing 1H-1,2,3-triazole compounds. And the patent contained the following:

The title method comprises the steps of: taking p-toluenesulfonyl azide, aryl acetylene, a catalyst, a ligand and a solvent as a reaction system, performing reaction at 20-30°C under magnetic stirring for 10-60 min, adding a small amount of water into the reaction solution, heating, carrying out reaction at 80-130°C under magnetic stirring for 1-20 h, cooling reaction solution to room temperature, extracting, washing the organic layer, drying, vacuum distilling to remove solvent and obtain crude product, and separating and purifying by column chromatog. to obtain the the title product. According to this invention, inexpensive and easily available p-toluenesulfonyl azide and aryl acetylene are used as substrates, and NH-1,2,3-triazole compound can be easily and effectively synthesized under catalyst action. The method has the advantages of mild reaction condition, short reaction time, high safety, convenient operation, high reaction efficiency and low catalyst cost, and has potential application value. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Electric Literature of 5301-96-2

The Article related to triazole preparation cyclization, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Electric Literature of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On November 23, 2016, Wu, Luyong; Wang, Xianghui; Hui, Yang; Lin, Qiang; Huang, Qinglan; Tan, Zhiqiang published a patent.COA of Formula: C9H9N3 The title of the patent was Synthetic method of NH-1,2,3-triazole compound. And the patent contained the following:

The present invention relates to synthetic method of NH-1,2,3-triazole. The method comprises the steps of: carrying out one-pot reaction of aldehyde, nitro compound, sodium azide, solvent and additive for 1-8 h at 80-150 °C, and carrying out post treatment after reaction to obtain NH-1,2,3-triazole. With cheap and easily available aldehyde, nitro compound and sodium azide as raw materials, NH-1,2,3-triazole compound is easily prepared The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).COA of Formula: C9H9N3

The Article related to synthetic triazole compound, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.COA of Formula: C9H9N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Kim, Ji Dang; Palani, Thiruvengadam; Kumar, Manian Rajesh; Lee, Sunwoo; Choi, Hyun Chul published an article in 2012, the title of the article was Preparation of reusable Ag-decorated graphene oxide catalysts for decarboxylative cycloaddition.Related Products of 5301-96-2 And the article contains the following content:

In this study, we demonstrated a noble Ag-decorated graphene oxide catalyst (GOSH-Ag) for use in the decarboxylative cycloaddition reaction. The catalyst was easily prepared by depositing Ag nanoparticles on thiolated graphene oxide (GOSH) surfaces. Transmission electron microscopy (TEM) indicated that the nanoparticles were well-dispersed and of a small, approx. 3.7 nm average size. These characteristics resulted in a high surface area, which enhanced the catalytic activity of the supported catalyst. Moreover, it was found that the aggregation of Ag catalysts was inhibited by the strong adhesion between the GOSHs and the Ag nanoparticles during the chem. reactions, thereby permitting their reuse. Indeed, the supported catalyst could easily be separated and recovered from the reaction mixture and reused several times. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Related Products of 5301-96-2

The Article related to reusable silver graphene oxide catalyst decarboxylative cycloaddition, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Related Products of 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Shibl, Mohamed F.; Elroby, Shabaan A. K.; Hilal, Rifaat H. published an article in 2011, the title of the article was Solvent and substituent effects on the electronic structures of triazoles: computational study.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

The tautomerization reaction of 1,2,3-triazole and some of its derivatives was studied and the transition states were located. The anal. of results indicates that 2H-triazole is more stable than the 1H-tautomer in all studied compounds in gas phase and in solution The p detachment energies and the geometries of the compounds studied were analyzed using d. functional theory (DFT) and Hartree-Fock (HF) methods in gas phase and solution Deprotonation takes place in all cases studied by the detachment of N-H p. The solvent effect on the stability the tautomeric and anion forms of studied compounds was examined using B3LYP/6-31G* level of theory by applying the polarizable continuum model. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to solvent substituent effect electronic structure triazole tautomerization, dft hartree fock transition state benzotriazole tautomerization, Physical Organic Chemistry: Rearrangements, Including Isomerization and Tautomerization and other aspects.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Hauptmann, Siegfried; Wilde, Horst published an article in 1976, the title of the article was Substituent effects on the polarographic reduction of 1-amino-4-aryl-1,2,3-triazoles and 1H-4-aryl-1,2,3-triazoles.Formula: C9H9N3 And the article contains the following content:

Cathodic half-wave potentials (E1/2) for I (R = NH2, H; X = p-F, p-Cl, p-Br, p-Me, etc.), determined in MeCN at 20°, were between -2.1 and -2.6 V. Linear relations were found between E1/2 and the π-electron d. at C(5), as well as Hammett σ values. Pos. ρ values indicate a nucleophilic mechanism. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Formula: C9H9N3

The Article related to reduction electrochem triazole mechanism, reaction constant electrochem reduction, Physical Organic Chemistry: Oxidation-Reduction Reactions (Including Hydrogenation) and other aspects.Formula: C9H9N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On August 14, 2020, Yadav, Chetna; Maka, Vijay Kumar; Payra, Soumen; Moorthy, Jarugu Narasimha published an article.Recommanded Product: 5301-96-2 The title of the article was De Novo Access to SO3H-Grafted Porous Organic Polymers (POPs@H): Synthesis of Diarylbenzopyrans/Naphthopyrans and Triazoles by Heterogeneous Catalytic Cyclocondensation and Cycloaddition Reactions. And the article contained the following:

Covalent polymerization of contrived mol. building blocks leads to porous organic polymers (POPs) with intrinsic. Leveraging the results of our extensive investigations with mol. systems based on twisted biaryl scaffold as applied to metal-organic frameworks (MOFs) and organic light-emitting diodes (OLEDs), we envisioned that the Fridel-Crafts polyalkylation of the 2,2′,6,6′-tetramethylbiphenyl core with α,α’-dichloro-p-xylene should lead to a hypercrosslinked polymer with assured porosity. Furthermore, sulfonation of the latter in a postsynthetic fashion was surmised to yield a POP grafted with sulfonic acid groups for catalysis. Indeed, the polyalkylation of tetramethylbiphenyl led to a highly porous POP (MeBP) with a BET surface area of 1277 m2 g-1. Also, its sulfonated derivative (MeBP@H) exhibited a surface area of 766 m2 g-1, as determined by N2 sorption anal. Polymer MeBP@H with palpable porosity and endowed with Bronsted acid sites installed through sulfonation was explored for the heterogeneous catalysis of cyclocondensation and cycloaddition reactions in a recyclable fashion. We show that MeBP@H exhibits exceptionally high catalytic activity in the synthesis of a wide variety of photochromic diarylbenzopyrans/naphththopyrans and pharmacol. relevant triazoles at room temperature Diverse functional groups are shown to be tolerated in both condensation and cycloaddition reactions. The catalyst is found to be efficient for the synthesis of triazoles having both electron-rich and electron-poor functionalities. Although a variety of methods are known in the literature for the synthesis of both diarylbenzopyrans/naphthopyrans and triazoles, MeBP@H allows the reactions to be conducted in shorter reaction times and very cleanly, leading to the isolation of products with high operational simplicity. The catalyst can be isolated back by filtration and recycled; indeed, MeBP@H is shown to be recycled for at least 10 catalytic cycles for both reactions without any loss of efficiency. Addnl., MeBP and MeBP@H are found to exhibit higher uptake capacities for CO2 and C2H2 over N2 at 298 K and inverse uptake capacity for C2H2 over CO2. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 5301-96-2

The Article related to diarylbenzopyran naphthopyran triazole heterogeneous catalytic cyclocondensation cycloaddition, Chemistry of Synthetic High Polymers: Ring-Opening and Other Polymerizations and other aspects.Recommanded Product: 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On September 30, 2017, Bhagat, Ujjawal Kumar; Peddinti, Rama Krishna published an article.Recommanded Product: 5301-96-2 The title of the article was Base-Mediated Ring Opening of meso-Epoxides with 4-Aryl-NH-1,2,3-triazoles: Synthesis of trans-2-(Aryltriazolyl)cycloalkanols. And the article contained the following:

A novel method of nucleophilic ring-opening of meso-epoxides with 4-aryl-NH-1,2,3-triazoles has been developed under metal-free conditions. The epoxide-ring opening process was carried out in the presence of organic bases (DABCO/Et3N) in acetonitrile at 85°C to afford a regioisomeric mixture of trans-2-(4-aryl-2H-1,2,3-triazol-2-yl)cycloalkanols (2,4-disubstituted triazoles) as major adducts and trans-2-(4-aryl-1H-1,2,3-triazol-1-yl)cycloalkanols (1,4-disubstituted triazoles) as minor adducts in excellent combined chem. yields (isolated yield up to 99%). The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Recommanded Product: 5301-96-2

The Article related to ring opening nucleophilic regioselective meso epoxide aryltriazole, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Recommanded Product: 5301-96-2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On March 18, 2022, Jankovic, Dominik; Virant, Miha; Gazvoda, Martin published an article.Category: triazoles The title of the article was Copper-Catalyzed Azide-Alkyne Cycloaddition of Hydrazoic Acid Formed In Situ from Sodium Azide Affords 4-Monosubstituted-1,2,3-Triazoles. And the article contained the following:

Authors report a copper-catalyzed cycloaddition of hydrogen azide (hydrazoic acid, HN3) with terminal alkynes to form 4-substituted-1,2,3-triazoles in a sustainable manner. Hydrazoic acid was formed in situ from sodium azide under acidic conditions to react with terminal alkynes in a copper-catalyzed reaction. Using polydentate N-donor chelating ligands and mild organic acids, the reactions were realized to proceed at room temperature under aerobic conditions in a methanol-water mixture and with 5 mol % catalyst loadings to afford 4-substituted-1,2,3-triazoles in high yields. This method is amenable on a wide range of alkyne substrates, including unprotected peptides, showing diverse functional group tolerance. It is applicable for late-stage functionalization synthetic strategies, as demonstrated in the synthesis of the triazole analog of losartan. The preparation of orthogonally protected azahistidine from Fmoc-L-propargylglycine was realized on a gram scale. The hazardous nature of hydrazoic acid has been diminished as it forms in situ in <6% concentrations at which it is safe to handle. Reactions of distilled solutions of hydrazoic acid indicated its role as a reactive species in the copper-catalyzed reaction. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Category: triazoles

The Article related to triazole preparation green chem, azide alkyne cycloaddition copper, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: triazoles

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics