Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 584-13-4, name is 4H-1,2,4-Triazol-4-amine, A new synthetic method of this compound is introduced below., HPLC of Formula: C2H4N4
The mixture of compound 5 (0.01 mol), 4-amino-1,2,4-triazole (0.01 mol), KOH (0.02 mol) in 10-15 mL of dioxanewas heated at 80-100oC for 7-8 h. The solvent was evaporatedand the residue was processed with ether. The part,which was not dissolved in the ether, was neutralized withacetic acid, and the precipitate was filtered off. White crystals;yield 89%, mp 224-225oC. 1H NMR: delta 2.29 (brs, 3H,CH3-pyrim.); 2.31 (s, 3H, SCH3); 3.20 (brs, NH+H2O of solven);5.99 (brs, 1H, CH-pyrim.); 8.40 (s, 2H, 2¡ÁCH-triaz.).Anal. calcd for C8H10N6S: C, 43.23; H, 4.54; N, 37.81;found: C, 43.12; H, 4.45; N, 37.60%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Ayvazyan, Armen G.; Azaryan, Zhermen A.; Ghazaryan, Emma A.; Pivazyan, Vergush A.; Tamazyan, Rafael A.; Yengoyan, Aleksandr P.; Letters in Organic Chemistry; vol. 17; 2; (2020); p. 149 – 156;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics