Reference of 584-13-4, A common heterocyclic compound, 584-13-4, name is 4H-1,2,4-Triazol-4-amine, molecular formula is C2H4N4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
An EtOH solution of 4-amino-1,2,4-triazole (1.26 g, 15 mmol) and 2-pyridinecarboxaldehyde (1.61 g, 15 mmol) was refluxed for 3 h, a large amount of precipitate of the ligand L was filtered off after cooling and dried under vacuum. Yield 80%, 2.08 g. Anal. Calcd. (%) for C8H7N5: C, 55.49; H, 4.04; N, 40.46. Found: C, 55.53; H, 3.97; N, 40.40. IR (cm-1, KBr pellet): 3094 (s), 1617 (w), 1587 (m), 1503 (s), 1475 (s), 1439 (m), 1392 (w), 1315 (w), 1287 (m), 1223 (m), 1173 (s), 1093 (w), 1058 (s), 995 (m), 982 (w), 964 (w), 939 (w), 869 (m), 781 (s), 760 (w), 743 (m), 622 (s), 521 (m), 505 (w).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Dang, Dong-Bin; Li, Meng-Meng; Bai, Yan; Zhou, Rui-Min; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 103; (2013); p. 101 – 107;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics