Category: Triazoles

Campos, Joana F. published the artcileA greener and efficient method for nucleophilic aromatic substitution of nitrogen-containing fused heterocycles, Quality Control of 24415-66-5, the main research area is chloro heteroarenopyrimidine amine nucleophilic aromatic substitution green chem; amino heteroarenopyrimidine preparation; PEG-400; nitrogen fused heterocycles; nucleophilic aromatic substitution.

A simple and efficient methodol. for the nucleophilic aromatic substitution of nitrogen-containing fused heterocycles with interesting biol. activities was developed in an environmentally sound manner using polyethylene glycol (PEG-400) as the solvent, lead to the expected compounds in excellent yields only in five minutes.

Molecules published new progress about Aromatic nitrogen heterocycles Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Quality Control of 24415-66-5.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Schneider, Stefan published the artcileLiquid Azide Salts, Category: triazoles, the main research area is triazole amino azide crystal structure thermal stability ionic liquid.

Ionic liquid azides from azidoethyl, alkyl, and alkenyl substituted derivatives of amino-1,2,4- and -1,2,3-triazoles were prepared and examined for the first time to investigate their structural and phys. properties. All reported salts possess m.ps. below 100 °C. The unique character of these newly discovered ionic liquid azides is based upon the fact that these mols. are not simple protonated salts like previously reported substituted hydrazinium azides. The presence of quaternary nitrogen confers both thermal stability and negligible volatility.

Inorganic Chemistry published new progress about Azides Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 39602-93-2 belongs to class triazoles, name is 4-Amino-1-methyl-4H-1,2,4-triazol-1-ium iodide, and the molecular formula is C3H7IN4, Category: triazoles.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Campos, Joana F. published the artcileEucalyptol as bio-based solvent for Migita-Kosugi-Stille coupling reaction on O,S,N-heterocycle, Application In Synthesis of 24415-66-5, the main research area is eucalyptol heterocycle Migita Kosugi Stille coupling solvent green.

We report herein an investigation on the use of eucalyptol as new solvent for organic transformations applied to the Migita-Kosugi-Stille palladium-catalyzed cross-coupling reaction. Heterocycles containing oxygen, sulfur and nitrogen were chosen as starting materials. Eucalyptol turned out to be a viable sustainable alternative to common solvents for this reaction.

Catalysis Today published new progress about Aryl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent) (heteroaryl). 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Application In Synthesis of 24415-66-5.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Hu, Yongke published the artcileEfficient and selective palladium-catalyzed direct oxidative esterification of benzylic alcohols under aerobic conditions, COA of Formula: C9H9N3O, the main research area is aliphatic benzylic alc oxidative esterification palladium; alkyl benzoate preparation; palladium oxidative esterification catalyst.

A highly efficient palladium-catalyzed approach for the direct oxidative esterification of benzylic alcs. with methanol and long-chain aliphatic alcs. under mild conditions has been achieved. This practical catalyst system exhibits a broad substrate scope and good functional group tolerance. Catalytic amount of Bi(OTf)3 is used as co-catalyst to improve the activity and selectivity of the reactions. A variety of esters are obtained in yields of 43-96%.

Tetrahedron published new progress about Aliphatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 143426-50-0 belongs to class triazoles, name is 4-(1,2,4-Triazol-1-yl)benzyl Alcohol, and the molecular formula is C9H9N3O, COA of Formula: C9H9N3O.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Hu, Yongke published the artcilePractical CuCl/DABCO/4-HO-TEMPO-catalyzed oxidative synthesis of nitriles from alcohols with air as oxidant, Application In Synthesis of 143426-50-0, the main research area is copper chloride DABCO TEMPO oxidation alc; nitrile preparation green.

A mild and efficient methodol. for the direct oxidative synthesis of nitriles from easily available alcs. and aqueous ammonia by employing CuCl/DABCO/4-HO-TEMPO as the catalysts is described. This protocol uses the air as a green oxidant and aqueous ammonia as the nitrogen source at room temperature A variety of aryl, heterocyclic and allylic alcs. are smoothly converted into the corresponding nitriles in good to excellent yields.

Chinese Chemical Letters published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 143426-50-0 belongs to class triazoles, name is 4-(1,2,4-Triazol-1-yl)benzyl Alcohol, and the molecular formula is C9H9N3O, Application In Synthesis of 143426-50-0.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Fuerstner, Alois published the artcileIron-Catalyzed Cross-Coupling Reactions, Quality Control of 24415-66-5, the main research area is iron complex cross coupling catalyst organometallic compound; aryl chloride triflate tosylate coupling iron catalyst; heteroaryl chloride triflate tosylate coupling iron catalyst; green chem iron complex cross coupling catalyst.

Simple iron salts such as FeCln, Fe(acac)n (n = 2,3) or the salen complex I turned out to be highly efficient, cheap, toxicol. benign, and environmentally friendly precatalysts for a host of cross-coupling reactions of alkyl or aryl Grignard reagents, zincates, or organomanganese species with aryl and heteroaryl chlorides, triflates, and even tosylates. An “”inorganic Grignard reagent”” of the formal composition [Fe(MgX)2], prepared in situ, likely constitutes the propagating species responsible for the catalytic turnover, which occurs in many cases at an unprecedented rate even at or below room temperature Because of the exceptionally mild reaction conditions, a series of functional groups such as esters, ethers, nitriles, sulfonates, sulfonamides, thioethers, acetals, alkynes, and -CF3 groups are compatible. The method also allows for consecutive cross-coupling processes in one pot, as exemplified by the efficient preparation of compound II, and has been applied to the first synthesis of the cytotoxic marine natural product montipyridine (III). In contrast to the clean reaction of (hetero)aryl chlorides, the corresponding bromides and iodides are prone to a reduction of their C-X bonds in the presence of the iron catalyst.

Journal of the American Chemical Society published new progress about Aryl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Quality Control of 24415-66-5.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Campos, Joana F. published the artcileEucalyptol as new solvent for the synthesis of heterocycles containing oxygen, sulfur and nitrogen, Name: 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, the main research area is fused heterocyclic compound one pot preparation green chem.

The first investigation of the use of eucalyptol as a new solvent for organic transformations was reported. Heterocycles containing oxygen, sulfur and nitrogen were chosen as targets or as starting materials for widely used palladium-catalyzed cross-coupling reactions, i.e. Suzuki-Miyaura and Sonogashira-Hagihara reactions. Eucalyptol turned out to be a viable sustainable alternative to common solvents.

Green Chemistry published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 24415-66-5 belongs to class triazoles, name is 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine, and the molecular formula is C6H5ClN4, Name: 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Panmand, Deepak S. published the artcileSynthesis and Direct C2 Functionalization of Imidazolium and 1,2,4-Triazolium N-Imides, Recommanded Product: 4-Amino-1-methyl-4H-1,2,4-triazol-1-ium iodide, the main research area is aryl imidazolpyrazolole pyrazolotriazole imidazoliumylamide triazoliumylamide preparation fluorescence emission spectra; azoliumimide acetylene aryl iodide arylation alkynylation cyclization.

Pd-catalyzed direct C2 arylation and Cu-catalyzed direct one-pot alkynylation/intramol. cyclization of azolium N-imides are reported. Various acetylenes, aryl iodides, and 1-alkyl substituents were examined The mild protocol allows direct C2 arylation of azolium N-imides without the use of specialized reagents together with novel one-pot regioselective preparations of imidazole-pyrazolo e. g., I, and pyrazolo-1,2,4-triazole e. g., II ring systems. The electronic properties of selected examples were examined by fluorescence spectroscopy.

Journal of Organic Chemistry published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 39602-93-2 belongs to class triazoles, name is 4-Amino-1-methyl-4H-1,2,4-triazol-1-ium iodide, and the molecular formula is C3H7IN4, Recommanded Product: 4-Amino-1-methyl-4H-1,2,4-triazol-1-ium iodide.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Larson, Helen published the artcileNi-Catalyzed C-H Arylation of Oxazoles and Benzoxazoles Using Pharmaceutically Relevant Aryl Chlorides and Bromides, Synthetic Route of 108281-78-3, the main research area is nickel catalyst arylation oxazole benzoxazole pharmaceutically relevant aryl halide.

This manuscript details the development of the nickel-catalyzed arylation of oxazoles and benzoxazoles with aryl halides. A series of aryl, heteroaryl, and druglike electrophiles relevant to pharmaceutical applications were surveyed. The desired arylated products were obtained in synthetically useful yields using electronically and structurally varied aryl halides. The use of microscale high-throughput experimentation was essential for both the rapid identification of optimal reaction parameters and the investigation of the aryl halide scope.

Journal of Organic Chemistry published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 108281-78-3 belongs to class triazoles, name is 6-Bromo-3-methyl-[1,2,4]triazolo[4,3-a]pyridine, and the molecular formula is C7H6BrN3, Synthetic Route of 108281-78-3.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Jishkariani, Davit published the artcileCu(I)-Catalyzed Regioselective Synthesis of Pyrazolo[5,1-c]-1,2,4-triazoles, SDS of cas: 39602-93-2, the main research area is terminal alkyne triazolium imide regioselective cycloaddition copper; regioselective preparation; copper regioselective cycloaddition catalyst.

Cycloadditions of terminal alkynes to 1,2,4-triazolium N-imides in the presence of base and Cu(I) afford pyrazolo[5,1-c]-1,2,4-triazoles, e.g., I, regioselectively. The scope of alkynes, the influence of the electronic nature of the leaving group, and variations in the 1-alkyl substituent were examined Quantum chem. calculations were employed to explain the distinct reactivity of the propiolates.

Journal of Organic Chemistry published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 39602-93-2 belongs to class triazoles, name is 4-Amino-1-methyl-4H-1,2,4-triazol-1-ium iodide, and the molecular formula is C3H7IN4, SDS of cas: 39602-93-2.

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics