Category: Triazoles

Hung, Jui-Yi’s team published research in Journal of Materials Chemistry in 20 | CAS: 219508-27-7

Journal of Materials Chemistry published new progress about 219508-27-7. 219508-27-7 belongs to triazoles, auxiliary class Trifluoromethylated Building Blocks, name is 2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine, and the molecular formula is C8H5F3N4, Recommanded Product: 2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine.

Hung, Jui-Yi published the artcilePhosphorescent Ir(III) Complexes Bearing Double Benzyldiphenylphosphine Cyclometalates; Strategic Synthesis, Fundamental and Integration for White OLED Fabrication, Recommanded Product: 2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine, the publication is Journal of Materials Chemistry (2010), 20(36), 7682-7693, database is CAplus.

A new Ir(III) complex [Ir(bdp)2(OAc)] (1) was prepared by the treatment of IrCl3(tht)3 with approx. two equiv of benzyldiphenylphosphine in refluxing decalin solution(bdpH = benzyldiphenylphosphine and tht = tetrahydrothiophene). Complex 1 proves to be a versatile precursor, which could further react with various triazolate chelates such as 5-pyridyl-3-trifluoromethyl-1,2,4-triazole (fptzH), 3-tert-butyl-5-(2-pyridyl)-1,2,4-triazole (bptzH), 5-(1-isoquinolyl)-3-tert-butyl-1,2,4-triazole (iqbtzH) and 5-(1-phenanthridinyl)-3-tert-butyl-1,2,4-triazole (pbtzH) to afford the emissive complexes [Ir(bdp)2(fptz)] (2), [Ir(bdp)2(bptz)] (3), [Ir(bdp)2(iqbtz)] (4), and [Ir(bdp)2(phbtz)] (5), resp. Single crystal x-ray diffraction studies of 1 and 5 revealed a distorted octahedral Ir(III) metal core; both possess two mutually orthogonal bdp cyclometalates, and the resp. PPh2 donors reside at the cis-orientation. Formation of complexes 2–5 can be envisioned as simple replacement of acetate with the incoming N-heterocyclic triazolate chelates. As for photophys. properties, the structural variation leads to salient differences in emission features among complexes 2–5. Combining theor. approaches, the results are rationalized by the contribution from the degree of ligand π-conjugation, together with the occurrence of ligand-to-ligand charge transfer (LLCT) and intra-ligand ππ* transition in the lowest lying excited state. The orange-red and white light-emitting OLEDs were then fabricated using 5 as dopant, for which the resp. devices gave peak efficiencies of 13.6% photons/electron, 33.3 cd A-1, 29.8 lm/W and with CIEx,y = 0.530, 0.467 at 100 cd m-2, and peak efficiencies of 13.0% photons/electron, 28.0 cd A-1, 22.8 lm/W, and with CIEx,y = 0.356, 0.348 at 1000 cd m-2.

Journal of Materials Chemistry published new progress about 219508-27-7. 219508-27-7 belongs to triazoles, auxiliary class Trifluoromethylated Building Blocks, name is 2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine, and the molecular formula is C8H5F3N4, Recommanded Product: 2-[5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl]pyridine.

Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics

Subiros-Funosas, Ramon et al. published their research in Chimica Oggi in 2008 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Category: triazoles

PyClocK, the phosphonium salt derived from 6-Cl-HOBt was written by Subiros-Funosas, Ramon;Moreno, Juan A.;Bayo-Puxan, Nuria;Abu-Rabeah, Khalil;Ewenson, Ariel;Atias, Danit;Marks, Robert S.;Albericio, Fernando. And the article was included in Chimica Oggi in 2008.Category: triazoles The following contents are mentioned in the article:

Novel phoshphonium salts of benzotriazoles, which are highly reactive coupling agents, and are particularly useful in peptide synthesis, are described. Further described is a process of preparing the novel phosphonium salts and methods for preparing peptides. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Category: triazoles).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. The presence of the three nitrogen atoms in triazole structures afforded opportunities for a plethora of structural modification with the generation of novel therapeutically potential agents, which is different from other heterocyclic compounds.Category: triazoles

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Garcia-Martin, Fayna et al. published their research in Peptide Science in 2010 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeRecommanded Product: ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)

Novel coupling method for the incorporation of ‘complex’ amino acid was written by Garcia-Martin, Fayna;Hinou, Hiroshi;Matsushita, Takahiko;Nishimura, Shin-ichiro. And the article was included in Peptide Science in 2010.Recommanded Product: ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) The following contents are mentioned in the article:

A symposium report. Novel coupling method for glycosylated amino acids (models for “complex” amino acids) relies on the synergy of microwave energy, incorporation of only 1.2 equiv of amino acid, PEG-containing resins and “double-activation” method. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Recommanded Product: ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeRecommanded Product: ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Carpino, Louis A. et al. published their research in Tetrahedron Letters in 1994 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeElectric Literature of C17H27F6N7OP2

Racemization studies during solid-phase peptide synthesis using azabenzotriazole-based coupling reagents was written by Carpino, Louis A.;El-Faham, Ayman;Albericio, ernando. And the article was included in Tetrahedron Letters in 1994.Electric Literature of C17H27F6N7OP2 The following contents are mentioned in the article:

1-Hydroxy-7-azabenzotriazole (HOAt) (I) and its corresponding uronium salts are more effective in avoiding racemization in a model solid-phase peptide segment coupling process than their benzotriazole analogs. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Electric Literature of C17H27F6N7OP2).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeElectric Literature of C17H27F6N7OP2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Katritzky, Alan R. et al. published their research in ARKIVOC (Gainesville, FL, United States) in 2004 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Safety of ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)

N-acylation in combinatorial chemistry was written by Katritzky, Alan R.;Suzuki, Kazuyuki;Singh, Sandeep K.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2004.Safety of ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) The following contents are mentioned in the article:

A review. Polymer-supported N-acylation utilizing carbodiimides with additives, direct coupling reagents (phosphonium salts and uronium salts), N-acylazoles, and other reagents are discussed. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Safety of ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Safety of ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Zhang, Wei et al. published their research in Journal of Peptide Science in 2009 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Recommanded Product: 156311-83-0

Synthesis of the C-terminal pentapeptide of the peptaibol culicinins was written by Zhang, Wei;Sun, Tian-Tian;Li, Ying-Xia. And the article was included in Journal of Peptide Science in 2009.Recommanded Product: 156311-83-0 The following contents are mentioned in the article:

The synthesis of the C-terminal pentapeptide of culicinins has been achieved using [4 + 1] protocol and reduction-coupling strategy. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Recommanded Product: 156311-83-0).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Many triazoles are versatile, biologically active compounds commonly used as fungicides and plant retardants.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Recommanded Product: 156311-83-0

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Gibertson, Scott R. et al. published their research in Chemtracts in 2001 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Triazoles consist of a five-membered ring containing three nitrogen atoms and are biologically active, especially as antifungal, antimicrobial and enzyme inhibitors. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeSDS of cas: 156311-83-0

Reaction microarrays: a method for rapidly determining the enantiomeric excess of thousands of samples was written by Gibertson, Scott R.. And the article was included in Chemtracts in 2001.SDS of cas: 156311-83-0 The following contents are mentioned in the article:

The title research (of G. A. Gorber, et al., 2001) is reviewed with commentary and 21 references This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0SDS of cas: 156311-83-0).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Triazoles consist of a five-membered ring containing three nitrogen atoms and are biologically active, especially as antifungal, antimicrobial and enzyme inhibitors. Triazole growth retardants such as uniconazole and paclobutrazol have been known to inhibit the biosynthesis of gibberellins by blocking kaurene oxidase, an P450 enzymeSDS of cas: 156311-83-0

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Nicolaou, K. C. et al. published their research in Angewandte Chemie, International Edition in 2005 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Triazoles are important five-member nitrogen heterocycles involved in a wide range of industrial applications such as agrochemicals, corrosion inhibitors, dyes, optical brighteners, as well as biologically active agents. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Category: triazoles

Total synthesis of halipeptins A and D and analogues was written by Nicolaou, K. C.;Kim, David W.;Schlawe, Daniel;Lizos, Dimitrios E.;de Noronha, Rita G.;Longbottom, Deborah A.. And the article was included in Angewandte Chemie, International Edition in 2005.Category: triazoles The following contents are mentioned in the article:

Deceptive rings: Halipeptins A I (R2 = CH2OH) and D I (R2 = Me) and analogs thereof were synthesized from azide fragment II and ester fragment III (R = OSiPh2CMe3, H, resp.). Key steps included peptide-bond formation, DAST-induced thiazoline construction, and macrolactamization. Unlike the naturally isolated (and possibly contaminated) material, synthetic halipeptin D exhibited only weak toxicity against tumor cells. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Category: triazoles).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. Triazoles are important five-member nitrogen heterocycles involved in a wide range of industrial applications such as agrochemicals, corrosion inhibitors, dyes, optical brighteners, as well as biologically active agents. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Category: triazoles

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Bardhan, Sujata et al. published their research in Organic Letters in 2009 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Formula: C17H27F6N7OP2

Heteroaryl ethers by oxidative palladium catalysis of pyridotriazol-1-yloxy pyrimidines with arylboronic acids was written by Bardhan, Sujata;Wacharasindhu, Sumrit;Wan, Zhao-Kui;Mansour, Tarek S.. And the article was included in Organic Letters in 2009.Formula: C17H27F6N7OP2 The following contents are mentioned in the article:

The oxidative palladium-catalyzed cross-coupling of pyrimidines containing pyridotriazol-1-yloxy (OPt) as either a urea or an amide functional group with arylboronic acids in the presence of Cs2CO3 in DME containing 0.6-1.0% H2O is described for the preparation of heteroaryl ethers. The bromo substitution in the case of 3-(5-bromo-pyrimidin-2-yloxy)-3H-[1,2,3]triazolo[4,5-b]pyridine could serve as a handle for further elaborations such as Suzuki coupling for attaching varied aryl groups. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Formula: C17H27F6N7OP2).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. However, triazoles are also useful in bioorthogonal chemistry, because the large number of nitrogen atoms causes triazoles to react similar to azides.Triazole heterocyclic structures are found to form many weak nonbond interactions with the receptors and enzymes in biological systems.Formula: C17H27F6N7OP2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Xiao, Xiaoyin et al. published their research in Chemical Physics in 2006 | CAS: 156311-83-0

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Formula: C17H27F6N7OP2

Redox-gated electron transport in electrically wired ferrocene molecules was written by Xiao, Xiaoyin;Brune, Daniel;He, Jin;Lindsay, Stuart;Gorman, Christopher B.;Tao, Nongjian. And the article was included in Chemical Physics in 2006.Formula: C17H27F6N7OP2 The following contents are mentioned in the article:

We have synthesized cysteamine-terminated ferrocene mols. and determined the dependence of the electron transport properties of the mols. on their redox states by measuring the current through the mols. as a function of the electrode potential. The current fluctuates over a large range, but its average value increases with the potential. We attribute the current fluctuation and its increase with the potential to the switching of the mols. from low-conductance reduced state to high-conductance oxidized state. This study involved multiple reactions and reactants, such as ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0Formula: C17H27F6N7OP2).

((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V) (cas: 156311-83-0) belongs to triazole derivatives. The triazole ring is a relatively stable functional group, and the triazole bond can be used for a variety of applications, such as replacing the phosphate backbone of DNA. 1,2,3-Triazoles are usually prepared following (3+2) cycloaddition protocols. A common technique for unsubstituted triazoles is the Huisgen azide-alkyne 1,3-dipolar cycloaddition: a azide and an alkyne react at high temperature to form a ring. However, the Huisgen strategy produces a mixture of isomers (typically 1,4- and 1,5-disubstituted) when used to produce substituted triazoles.Formula: C17H27F6N7OP2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics