Category: Triazoles

Product Details of 61-82-5. Pisa, R; Cupido, T; Steinman, JB; Jones, NH; Kapoor, TM in [Pisa, Rudolf; Cupido, Tommaso; Steinman, Jonathan B.; Jones, Natalie H.; Kapoor, Tarun M.] Rockefeller Univ, Lab Chem & Cell Biol, New York, NY 10065 USA; [Pisa, Rudolf; Jones, Natalie H.] Rockefeller Univ, Triinst PhD Program Chem Biol, New York, NY 10065 USA; [Steinman, Jonathan B.] Weill Cornell Rockefeller Sloan Kettering Triinst, New York, NY 10065 USA published Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins in 2019.0, Cited 45.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Drug-like inhibitors are often designed by mimicking cofactor or substrate interactions with enzymes. However, as active sites are comprised of conserved residues, it is difficult to identify the critical interactions needed to design selective inhibitors. We are developing an approach, named RADD (resistance analysis during design), which involves engineering point mutations in the target to generate active alleles and testing compounds against them. Mutations that alter compound potency identify residues that make key interactions with the inhibitor and predict target-binding poses. Here, we apply this approach to analyze how diaminotriazole-based inhibitors bind spastin, a microtubule-severing AAA (ATPase associated with diverse cellular activities) protein. The distinct binding poses predicted for two similar inhibitors were confirmed by a series of X-ray structures. Importantly, our approach not only reveals how selective inhibition of the target can be achieved but also identifies resistance-conferring mutations at the early stages of the design process.

Product Details of 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Pisa, R; Cupido, T; Steinman, JB; Jones, NH; Kapoor, TM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Antiglycation Activity of Triazole Schiff’s Bases Against Fructose-mediated Glycation: In Vitro and In Silico Study WOS:000536018300011 published article about END-PRODUCTS; NONENZYMATIC GLYCATION; MAILLARD REACTION; ACCURATE DOCKING; LENS PROTEINS; INHIBITORS; DERIVATIVES; GLIDE; FRUCTOSYLATION; AMINOGUANIDINE in [Shaikh, Muniza; Zafar, Humaira; Subzwari, Fakiha; Imad, Rehan; Choudhary, Muhammad I.] Univ Karachi, Dr Panjwani Ctr Mol Med & Drug Res, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan; [Siddiqui, Salman; Naqeeb, Uzma; Khan, Khalid M.; Choudhary, Muhammad I.] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan; [Khan, Khalid M.] Imam Abdulrahman Bin Faisal Univ, Inst Res & Med Consultat IRMC, Dept Clin Pharm, POB 31441, Dammam, Saudi Arabia; [Choudhary, Muhammad I.] King Abdulaziz Univ, Dept Biochem, Fac Sci, Jeddah 21412, Saudi Arabia in 2020.0, Cited 59.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Formula: C2H4N4

Background: Advanced glycation end products (AGEs) are known to be involved in the pathophysiology of diabetic complications, neurodegenerative diseases, and aging. Preventing the formation of AGEs can be helpful in the management of these diseases. Objectives: Two classes of previously synthesized traizole Schiff’s bases (4H-1,2,4-triamle-4-Schiff’s bases 1-14, and 4H-1,2,4-triazole-3-Schiff’s bases 15-23) were evaluated for their in vitro antiglycation activity. Methods: In vitro fructose-mediated human serum albumin (HSA) glycation assay was employed to assess the antiglycation activity of triazole Schiff’s bases. The active compounds were subjected to cytotoxicity analysis by MTT assay on mouse fibroblast (3T3) cell line. Molecular docking and simulation studies were carried out to evaluate the interactions and stability of compounds with HSA. Anti-hyperglycemic and antioxidant activities of selected non-cytotoxic compounds were evaluated by in vitro a-glucosidase inhibition, and DPPH free radical scavenging assays, respectively. Results: Compound 1 (IC50 =47.30 +/- 0.38 mu M) from 4H-1,2,4-triazole-4-Schiff’s bases has exhibited antiglycation activity comparable to standard rutin (IC50 =54.5 +/- 0.05 mu M) along with a stable RMSD profile in MD simulation studies. Compound 1 also exhibited a potent a-glucosidase inhibitory activity, and moderate antioxidant property. Other derivatives showed a weak antiglycation activity with IC50 values between 248.1-637.7 mu M. Compounds with potential antiglycation profile were found to be non-cytotoxic in a cellular assay. Conclusion: The study identifies triazole Schiff s bases active against fructose-mediated glycation of HSA, thus indicates their potential against late diabetic complications due to production of advancedend products (AGEs).

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Shaikh, M; Siddiqui, S; Zafar, H; Naqeeb, U; Subzwari, F; Imad, R; Khan, KM; Choudhary, MI or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Mesoporous Polymeric Cyanamide-Triazole-Heptazine Photocatalysts for Highly-Efficient Water Splitting WOS:000558656000001 published article about GRAPHITIC CARBON NITRIDE; HYDROGEN EVOLUTION; FACILE SYNTHESIS; SEMICONDUCTORS; REDUCTION; NITROGEN; PERFORMANCE; PRECURSORS; NANOSHEETS; STRATEGY in [Wu, Chongbei; Yu, Guanhang; Yin, Yue; Wang, Yuze; Chen, Li; Han, Qing; Wang, Bo] Beijing Inst Technol, Key Lab Cluster Sci, Key Lab Photoelect Electrophoton Convers Mat, Minist Educ China,Sch Chem & Chem Engn, Beijing 100081, Peoples R China; [Tang, Junwang] UCL, Dept Chem Engn, London WC1E 7JE, England in 2020.0, Cited 65.0. HPLC of Formula: C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Conjugated polymers are promising light harvesters for water reduction/oxidation due to their simple synthesis and adjustable bandgap. Herein, both cyanamide and triazole functional groups are first incorporated into a heptazine-based carbon nitride (CN) polymer, resulting in a mesoporous conjugated cyanamide-triazole-heptazine polymer (CTHP) with different compositions by increasing the quantity of cyanamide/triazole units in the CN backbone. Varying the compositions of CTHP modulates its electronic structures, mesoporous morphologies, and redox energies, resulting in a significantly improved photocatalytic performance for both H(2)and O(2)evolution under visible light irradiation. A remarkable H(2)evolution rate of 12723 mu mol h(-1)g(-1)is observed, resulting in a high apparent quantum yield of 11.97% at 400 nm. In parallel, the optimized photocatalyst also exhibits an O(2)evolution rate of 221 mu mol h(-1) g(-1), 9.6 times higher than the CN counterpart, with the value being the highest among the reported CN-based bifunctional photocatalysts. This work provides an efficient molecular engineering approach for the rational design of functional polymeric photocatalysts.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wu, CB; Yu, GH; Yin, Y; Wang, YZ; Chen, L; Han, Q; Tang, JW; Wang, B or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2020.0 FLUID PHASE EQUILIBR published article about GREEN; MIXTURES; PARACETAMOL; IBUPROFEN in [Seyf, Jaber Yousefi] Hamedan Univ Technol, Dept Chem Engn, Hamadan, Hamadan, Iran; [Asgari, Mohammad] Sharif Univ Technol, Dept Chem Engn, Hamadan, Hamadan, Iran in 2020.0, Cited 26.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Quality Control of 1H-1,2,4-Triazol-5-amine

The recently reported UNIversal QUAsiChemical Segment Activity coefficient (UNIQUAC-SAC) model [developed by Haghtalab and Yousefi Seyf Ind. Eng. Chem. Res. 2015, 54, 8611] provides a practical thermodynamic framework to be used in VLE, LLE, and SLE calculations. The UNIQUAC-SAC model has the advantage of being independent of area (q) and volume (r) structural parameters used in the combinatorial part. While the UNIFAC or UNIFAC-DMD could not apply to the 47% (44 of 94) of the studied molecules because of the undefined groups. Here, the numbers of solvents with identified segment numbers were extended from 82 to 130 with a slight refinement to the previous values. The model parameters obtained via a large consistent set of VLE (isobaric and isothermal), and LLE experimental data. Also, the model was tested with pharmaceutical solubility experimental data in pure (94 solutes with 6210 solubility data), binary, and ternary solvents. The model provides a robust correlation of pharmaceuticals solubility in a mono-solvent and robust prediction of pharmaceuticals solubility in mixed solvents. The UNIQUAC-SAC model was successfully evaluated in solvent screening in cooling crystallization of ibuprofen and valsartan in both pure and binary solvents mixture (combined cooling and anti-solvent crystallization). The model with 130 solvents as a robust database provides a useful and practical thermodynamic tool in the conceptual design of pharmaceutical processes. A MATLAB based graphical user interface (GUI), finally, was developed to be used in the conceptual segment numbers regression procedure. (C) 2020 Elsevier B.V. All rights reserved.

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Seyf, JY; Asgari, M or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Plant Sciences very interesting. Saw the article Dual regulation of xylem formation by an auxin-mediated PaC3H17-PaMYB199 module in Populus published in 2020.0. Recommanded Product: 61-82-5, Reprint Addresses Chai, GH; Zhou, GK (corresponding author), Chinese Acad Sci, Qingdao Inst BioEnergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Peoples R China.; Chai, GH (corresponding author), Qingdao Agr Univ, Coll Resources & Environm, Qingdao 266109, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Wood (secondary xylem) formation in tree species is dependent on auxin-mediated vascular cambium activity in stems. However, the complex regulatory networks underlying xylem formation remain elusive. Xylem development in Populus was characterized based on microscopic observations of stem sections in transgenic plants. Transcriptomic, quantitative real-time PCR, chromatin immunoprecipitation PCR, and electrophoretic mobility shift assay analyses were conducted to identify target genes involved in xylem development. Yeast two-hybrid, pull-down, bimolecular fluorescence complementation, and co-immunoprecipitation assays were used to validate protein-protein interactions. PaC3H17 and its target PaMYB199 were found to be predominantly expressed in the vascular cambium and developing secondary xylem in Populus stems and play opposite roles in controlling cambial cell proliferation and secondary cell wall thickening through an overlapping pathway. Further, PaC3H17 interacts with PaMYB199 to form a complex, attenuating PaMYB199-driven suppression of its xylem targets. Exogenous auxin application enhances the dual control of the PaC3H17-PaMYB199 module during cambium division, thereby promoting secondary cell wall deposition. Dual regulation of xylem formation by an auxin-mediated PaC3H17-PaMYB199 module represents a novel regulatory mechanism in Populus, increasing our understanding of the regulatory networks involved in wood formation.

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Tang, XF; Wang, D; Liu, Y; Lu, MZ; Zhuang, YM; Xie, Z; Wang, CP; Wang, SM; Kong, YZ; Chai, GH; Zhou, GK or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Name: 1H-1,2,4-Triazol-5-amine. I found the field of Plant Sciences very interesting. Saw the article Dual regulation of xylem formation by an auxin-mediated PaC3H17-PaMYB199 module in Populus published in 2020.0, Reprint Addresses Chai, GH; Zhou, GK (corresponding author), Chinese Acad Sci, Qingdao Inst BioEnergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Peoples R China.; Chai, GH (corresponding author), Qingdao Agr Univ, Coll Resources & Environm, Qingdao 266109, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

Wood (secondary xylem) formation in tree species is dependent on auxin-mediated vascular cambium activity in stems. However, the complex regulatory networks underlying xylem formation remain elusive. Xylem development in Populus was characterized based on microscopic observations of stem sections in transgenic plants. Transcriptomic, quantitative real-time PCR, chromatin immunoprecipitation PCR, and electrophoretic mobility shift assay analyses were conducted to identify target genes involved in xylem development. Yeast two-hybrid, pull-down, bimolecular fluorescence complementation, and co-immunoprecipitation assays were used to validate protein-protein interactions. PaC3H17 and its target PaMYB199 were found to be predominantly expressed in the vascular cambium and developing secondary xylem in Populus stems and play opposite roles in controlling cambial cell proliferation and secondary cell wall thickening through an overlapping pathway. Further, PaC3H17 interacts with PaMYB199 to form a complex, attenuating PaMYB199-driven suppression of its xylem targets. Exogenous auxin application enhances the dual control of the PaC3H17-PaMYB199 module during cambium division, thereby promoting secondary cell wall deposition. Dual regulation of xylem formation by an auxin-mediated PaC3H17-PaMYB199 module represents a novel regulatory mechanism in Populus, increasing our understanding of the regulatory networks involved in wood formation.

Name: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Tang, XF; Wang, D; Liu, Y; Lu, MZ; Zhuang, YM; Xie, Z; Wang, CP; Wang, SM; Kong, YZ; Chai, GH; Zhou, GK or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 61-82-5. In 2021.0 CERAM INT published article about VISIBLE-LIGHT; HETEROJUNCTION; NANOSHEETS; OXIDATION; COMPOSITE; REMOVAL; GREEN; BIOI in [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Anhui Jianzhu Univ, Sch Environm & Energy Engn, Hefei 230601, Peoples R China; [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Anhui Prov Key Lab Environm Pollut Control & Reso, Hefei 230601, Peoples R China; [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Key Lab Water Pollut Control & Wastewater Reuse A, Hefei 230601, Peoples R China; [Feng, Li; Li, Xuhao; You, Weihong] Guangdong Univ Technol, Sch Civil & Transportat Engn, Guangzhou 510006, Guangdong, Peoples R China in 2021.0, Cited 63.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Bismuth oxyhalides (BiOX (X = Cl, Br, I) are considered to be an important p-type semiconductors in the photocatalysis applications. In particular, tetragonal BiOBr is considered as a stable photocatalyst due to its resilient absorption in the visible region with an band gap energy of 2.8 eV. In the meantime, lanthanide ions (with 3+ oxidation state) implies as conversion catalyst gained huge impact and remain a serious topic in materials chemistry. Here we synthesized upconversion photocatalyst mainly consists of BiOBr with the Er 3+ and Tb 3+ ions along with low band gap g-C3N5 for the improved photocatalytic performances. The synthesized Er3+/ Tb3+@BiOBr-g-C3N5 heterojunction was systematically characterized by XRD, and FT-IR for the confirmation of the composite and their morphology were analysed with FESEM and HR-TEM analysis which revealed that the sheets of g-C3N5 were decorated by Er3+/Tb3+ loaded BiOBr microspheres. The XPS analysis confirmed the suitable oxidation state of all the individual elements existing in the composite. As the UV-DRS analysis showed that the band gap of the Er3+/Tb3+ BiOBr-gC3N5 heterojunction was narrowed to 2.64 eV. To evaluate the photocatalytic efficiency of the synthesized g-C3N5, Er3+/Tb3+@BiOBr and Er3+/Tb3+@BiOBr-gC3N5 heterojunction under the simulated visible light irradiation source towards the aqueous sulfamethoxazole degradation. The Er3+/Tb3+@BiOBr-gC3N5 heterojunction shows maximum degradation efficiency of 94.2% after 60 min of visible light irradiation whereas the pure g-C3N5 provided about 43.8% and Er3+/Tb3+@BiOBr implies 55.2% degradation efficiency. The plausible degradation mechanism of pollutant removal was proposed.

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wei, W; Gong, HY; Sheng, L; Wu, HF; Zhu, SG; Feng, L; Li, XH; You, WH or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2020.0 SCI TOTAL ENVIRON published article about ELECTROCHEMICAL SENSOR; WO3 NANORODS; OXIDATION; NANOPARTICLES; BEHAVIOR; OXIDE; NANOTUBE; DRUG in [Ilager, Davalasab; Shetti, Nagaraj P.] KLE Inst Technol, Ctr Electrochem Sci & Mat, Dept Chem, Hubballi 580030, Karnataka, India; [Seo, Hyungtak; Kalanur, Shankara S.] Ajou Univ, Dept Mat Sci & Engn, Suwon 16499, South Korea; [Aminabhavi, Tejraj M.] SETs Coll Pharm, Pharmaceut Engn, Dharwad 580002, Karnataka, India in 2020.0, Cited 52.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. HPLC of Formula: C2H4N4

Environmental pollution by the heavy usage of pesticides has been a pandemic issue in view of the rising farming operations for increasing the crop yield to meet the requirements of food chain supply. Throughout the world, environmental pollution by the presence of pesticides, particularly the use of herbicides in large quantities to protect the crops, has posed many environmental issues. In this research, an electrochemical sensor based on tungsten oxide hydrates (WO3 center dot 0.33H(2)O) nanorod modified carbon paste electrode (CPE) was developed for the detection of herbicide, amitrole (AMT) by the cydic voltammeter. Hydrotheimally synthesized and characterized WO3 center dot 0.33H(2)O nanorod was found to be sensitive towards the detection of AMT due to its superior sensing property as the sensor showed enhanced current and catalytic property when used in phosphate buffer solution (PBS) of pH 5.0 by the cyclic voltammetric (CV) and square wave voltammetric (SWV) techniques. The influence of electro kinetic parameters viz., scan rate, pH, accumulation time and temperature with respect to AMT oxidation was studied using CV. The linearity range was in between 1.0 x 10(-8) M and 24 x 10(-5) M and limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 233 nM and 7.8 nM respectively. The proposed simple method demonstrated the potential applicability to detect AMT from the soil and water samples. (C) 2020 Elsevier B.V. All rights reserved.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ilager, D; Seo, H; Shetti, NP; Kalanur, SS; Aminabhavi, TM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

COA of Formula: C2H4N4. I found the field of Chemistry very interesting. Saw the article Efficient Synthesis and Antimicrobial Evaluation of New Azolopyrimidines-Bearing Pyrazole Moiety published in 2019.0, Reprint Addresses Gomha, SM (corresponding author), Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt.; Gomha, SM (corresponding author), Islamic Univ Almadinah Almonawara, Fac Sci, Dept Chem, Almadinah Almonawara 42351, Saudi Arabia.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

Sodium salt of 3-hydroxy-1-(1-aryl-5-methylpyrazolyl)propenone derivatives was used as a precursor for synthesis of various fused azolopyrimidine ring systems as pyrazolopyrimidines, triazolopyrimidines, and pyrimidobenzimidazoles following many procedures. The identity of the prepared compounds was elucidated by their spectral data and elemental analyses. The in vitro antimicrobial activity of 13 new compounds was evaluated, and many derivatives showed good to moderate activity.

COA of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Abdelhamid, AO; Gomha, SM; El-Enany, WAMA or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

HPLC of Formula: C2H4N4. In 2021.0 CRYST GROWTH DES published article about CRYSTAL-STRUCTURE; ACTINIDE; LANTHANIDE; SEPARATION; CHEMISTRY; COVALENCY; LIGAND in [Nayak, Amrita; Rogers, Robin D.] Univ Alabama, Coll Arts & Sci, Tuscaloosa, AL 35487 USA; [Smetana, Volodymyr; Mudring, Anja-Verena; Rogers, Robin D.] Stockholm Univ, Dept Mat & Environm Chem, S-10691 Stockholm, Sweden in 2021.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Continuing our investigations of ionic liquid (IL) based routes to a library of f-element/soft donor complexes which could be studied crystallographically, we have explored the dissolution of f-element salts in protic imidazole-based ILs containing only soft donors at high temperatures to drive off volatiles, including water and carboxylic or mineral acids. Here we present our results, reacting acidic and basic azoles in 1:3 or 1:1 stoichiometric compositions at elevated temperature, followed by saturation with Nd(OAc)(3)center dot xH(2)O or Ce(OAc)(3)center dot xH(2)O, which led to 13 new metal-acetate polymeric complexes identified by single-crystal X-ray diffraction. We found that the diversity in coordination modes of the simple acetate ligand that interfere with substitution of the softer N donors led to several readily crystallizable complexes forming two distinct groups with respect to f-element interaction with the ionic liquid precursors. When the acidic/basic azole ratio was 1:3, acetate and a neutral basic azole were found to be coordinated to the metal centers but no water, although in one case (2) water was observed in the secondary coordination sphere: [Ce(mu(2)-OAc)(3)(C(1)im)](n) (1, C(1)im = 1-methylimidazole), [Nd(mu(2)-(OAc)(3)(C(1)im)](n)center dot nH(2)O (2), [Ce(mu(2)-OAc)(3)(C(2)im)](n) (3, C(2)im = 1-ethylimidazole), [Ln(mu(2)-OAc)(3)DMF](n) (Ln = Nd (4), Ce (5); dimethylformamide (DMF) was substituted for the azole mixture), and [Nd(mu(2)-OAc)(3)(C(4)im)](n) (6, C(4)im = 1-butylimidazole). However, when the stoichiometric ratio was 1:1, water was always observed coordinated to the metal ions with the acidic azole included in the structure as a solvate or cocrystal, despite a higher reaction temperature: [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(1,2,3-Taz) (7,1,2,3-Taz = 1,2,3-triazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(4,5-DCim) (Ln = Nd (8), Ce (9), 4,5-DCim = 4,5-dicyanoimidazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(3,5-diNH(2)-1,2,4-Taz) (Ln = Nd (10), Ce (11), 3,5diNH(2)-1,2,4-Taz = 3,5-diamino-1,2,4-triazole), [Ce(mu(2)-OAc)(3)(OH2)](n)center dot n(3-NH2-1,2,4-Taz) (12, 3-NH2-1,2,4-Taz = 3-amino-1,2,4-triazole), and [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(5-NH2-Tz) (13, 5-NH2-Tz = 5-aminotetrazole). All of the compounds retain the Ln:OAc- ratio of 1:3 and form 1D polymeric chains; however, they exhibit a variety of coordination modes affecting the degree of chain condensation. The isolation of both hydrated and anhydrous products revealed different abilities of the investigated soft N-donors to compete with O-donors finding their place in the coordination sphere of the lanthanide or in the crystal lattice.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Nayak, A; Smetana, V; Mudring, AV; Rogers, RD or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics