Category: Triazoles

An article Novel bio-based core-shell organic-inorganic nanohybrid from embedding aspartic acid-guanine ionic liquid on the hydroxylated nano silica surface (nano [(Asp-Gua) IL@PEG-SiO2]): A versatile nanostructure for the synthesis of bis(2,3-dihydroquinazolin-4(1H)-one) derivatives and tricarboxamides under green media WOS:000523757900016 published article about MULTICOMPONENT REACTIONS; CATALYTIC APPLICATIONS; DESIGN; ANTICANCER; NANOCOMPOSITE in [Nikoofar, Kobra; Shahriyari, Fatemeh] Alzahra Univ, Fac Phys & Chem, Dept Chem, Tehran, Iran in 2020.0, Cited 47.0. Computed Properties of C2H4N4. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

A new multi-layered nano structure has been prepared using hydroxylated nano silica (as core) and novel guaninium aspartate ionic liquid (as shell) (nano [(Asp-Gua) IL@PEG-SiO2]). It characterized by FT-IR, H-1 NMR, FESEM, EDAX, XRD, TGA/ DTG, and BET analysis. This bio-based organic-inorganic hybrid catalyzed synthesis of peptide-like tricarboxamides though the pseudo five-component condensation of aromatic aldehydes, aromatic amines, tert-butyl isocyanide, and Meldrum’s acid under green solventless conditions at room temperature successfully. Its efficacy affirmed in the preparation of bis (2,3-dihydroquinazolin-4(1H)-one) derivatives via one-pot pseudo five-component reaction of aldehydes, amines, and isatoic anhydride in 70 degrees C aqueous media. The protocol contains several advantages such as relatively short reaction times, simple work-up procedure, economic and environmentally-friend because of performing the two class of MCRs under green media, utilizing wide-range of substrates, and reusability and recoverability of the core-shell nano-promoter for 3 runs without significant activity loss. (C) 2020 Published by Elsevier Ltd.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Nikoofar, K; Shahriyari, F or concate me.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Pore-size tuning in pillared-layer metal-organic framework with self-penetrated rob net for selective gas adsorption and efficient dyes adsorption in aqueous solution WOS:000474310000008 published article about COORDINATION POLYMERS; CRYSTAL-STRUCTURES; UNITS; SEPARATION; CH4; CO2; PERFORMANCE; STABILITY; TOPOLOGY; LIGANDS in [Liu, Jie; Wei, Yuhui; Bao, Fenlin; Li, Guixiang; Liu, Huiyan; Wang, Haiying] Jiangsu Normal Univ, Jiangsu Key Lab Green Synthet Chem Funct Mat, Sch Chem & Mat Sci, Xuzhou 221116, Jiangsu, Peoples R China in 2019.0, Cited 45.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Safety of 1H-1,2,4-Triazol-5-amine

Two metal-organic frameworks, [Zn-2(atrz)(2)(bpdc)]center dot 0.5H(2)O (1) and [Zn-2(mtrz)(2)(azdc)]center dot DMA center dot CH3OH center dot H2O (2), with 3-substitued 1,2,4-triazole (Hatrz = 3-amino-1,2,4-triazole, Hmtrz = 3-methyl-1,2,4-triazole) have been constructed. Both MOFs possess 3D self-penetrated frameworks featuring Zn-triazolate layers pillared by dicarboxylate ligands (H(2)bdc = 1,4-benzenedicarboxylate, H(2)azdc = azobenzene-4,4′-dicarboxylate). In particular, 2 exhibits a rare rob network with the dimeric Zn-triazolate as the 6-connected nodes, which resulted from the synergistic effects of both 3-substitued group of triazolate and size-alterable dicarboxylate pillar on the final frameworks. Detailed structural analysis of 1 and 2 and its comparison with commonly observed pcu net in pillared-layer structure has been presented. Pore-size tuning and functionalities have also been achieved related to diverse molecular length of pillars. 2 with long pillar displays suitable pore size, and consequently, demonstrates selective CO2 uptake and efficient dyes adsorption in aqueous solution based on size-exclusion effect. (C) 2019 Elsevier Ltd. All rights reserved.

Safety of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Liu, J; Wei, YH; Bao, FL; Li, GX; Liu, HY; Wang, HY or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2020.0 J BIOL INORG CHEM published article about OXYGEN SPECIES ROS; DNA-BINDING; LIGAND; CYTOTOXICITY; POTENT; SPECTROSCOPY; HETEROCYCLES; TRANSFERRIN; DERIVATIVES; RESISTANCE in [Fandzloch, Marzena] PAS, Inst Low Temp & Struct Res, Okolna 2, PL-50422 Wroclaw, Poland; [Fandzloch, Marzena; Jezierska, Julia] Univ Wroclaw, Fac Chem, F Joliot Curie 14, PL-50383 Wroclaw, Poland; [Dobrzanska, Liliana; Wisniewska, Joanna; Lakomska, Iwona] Nicolaus Copernicus Univ Torun, Fac Chem, Gagarina 7, PL-87100 Torun, Poland; [Jedrzejewski, Tomasz] Nicolaus Copernicus Univ Torun, Fac Biol & Vet Sci, Lwowska 1, PL-87100 Torun, Poland in 2020.0, Cited 80.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. SDS of cas: 61-82-5

Six novel ruthenium(III) complexes of general formula [RuCl3(L)(3)] (1,3,5) and [RuCl3(H2O)(L)(2)] (2,4,6), where L stands for three different triazolopyrimidine-derived ligands, are reported. The compounds have been structurally characterized (IR, EPR, SCXRD), and their magnetic moments have been determined. The single-crystal X-ray diffraction study revealed a slightly distorted octahedral geometry of the Ru(III) complexes with mer configuration in 1 and 5, and fac configuration in 3. In 2 and 4, three chloride ions are in mer configuration and the two triazolopyrimidines are oriented trans mutually with the water molecule playing the role of the sixth ligand. All complexes have been thoroughly screened for their in vitro cytotoxicity against human breast cancer cell line MCF-7, human cervical cancer cell line HeLa, and L929 murine fibroblast cells, uncovering among others that the most lipophilic complexes 5 and 6, containing the bulky ligand dptp (5,7-diphenyl-1,2,4-triazolo[1,5-a]pyrimidine), display high cytotoxic activity against MCF-7, and HeLa cells. Moreover, it was also revealed that during the interaction of the complexes 1-6 with the cancer MCF-7 cell line, reactive oxygen species are released intracellularly, which could indicate that they are involved in cell apoptosis. Furthermore, extensive studies have been carried out to reveal the mechanism by which complexes 1-6 interact with DNA, albumin, and apotransferrin. The biological studies were complemented by detailed kinetic studies of the hydrolysis of the complexes in the pH range 5-8, to determine the stability of the complexes in solution. Graphic abstract Six novel ruthenium(III) complexes with triazolopyrimidine derivatives demonstrated the potential for use as anticancer agents by maintaining the toxic effect on MCF-7 and HeLa cells.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Fandzloch, M; Dobrzanska, L; Jedrzejewski, T; Jezierska, J; Wisniewska, J; Lakomska, I or concate me.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 1H-1,2,4-Triazol-5-amine. In 2019.0 CHEM HETEROCYCL COM+ published article about DESIGN; INHIBITOR; POTENT; 5-AMINOPYRAZOLE; ANAGLIPTIN; DINACICLIB; ESSRAMYCIN; PYRAZOLE in [Gol, Ravindra M.; Barot, Vijaykumar M.] Smt SM Panchal Sci Coll, Dept Chem, Talod 383215, Gujarat, India; [Khatri, Taslimahemad T.] Govt Sci Coll, Dept Chem, Chikhli 396521, Gujarat, India in 2019.0, Cited 50.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Efficient and regioselective on-water synthesis of variously substituted 5-amino-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carbonitriles and 5-amino-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles using 1,8-diazabicyclo[5.4.0]undec-7-ene as catalyst has been demonstrated. The reaction of 2-benzylidenemalononitriles and 3-aryl-1H-pyrazol-5-amines or 1H-1,2,4-triazol-5-amine allows to obtain the respective pyrazolo[1,5-a]pyrimidines and [1,2,4]triazolo[1,5-a]pyrimidines in high yields up to 93%. Main advantages of the developed synthetic protocol are application of water as environmentally friendly solvent, short reaction times, simple workup procedure that often does not require further purification of products, and broad substrate scope.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Gol, RM; Khatri, TT; Barot, VM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Biochemistry & Molecular Biology; Chemistry; Pharmacology & Pharmacy very interesting. Saw the article A novel protocol for catalyst-free synthesis of fused six-member rings to triazole and pyrazole published in 2020.0. Product Details of 61-82-5, Reprint Addresses Karami, B (corresponding author), Univ Yasuj, Dept Chem, Yasuj 7591874831, Iran.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Herein, an effectual, quick and novel method is described for the synthesis of new triazolo[1,5-a]pyrimidine, triazolo[5,1-b][1,3] thiazine and pyrazolo[1,5-a]pyrimidine derivatives. This series of fused six-member rings to triazole and pyrazole was prepared via the catalyst-free reaction of dialkyl acetylenedicarboxylates and 3-substituted 1H-1,2,4-triazole or 3-amino-1H-pyrazole-4-carbonitrile. The structures of the prepared products were deduced from their Fourier-transform infrared, elemental analysis and proton and carbon-13 nuclear magnetic resonance spectral data. Graphical abstract A novel and green method is described for the synthesis of new triazolo[1,5-a]pyrimidine, triazolo[5,1-b][1,3] thiazine and pyrazolo[1,5-a]pyrimidine derivatives. [GRAPHICS] .

Product Details of 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Akrami, S; Karami, B; Farahi, M or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Cobalt oxide nanoparticles anchored polyaniline-appended cobalt tetracarboxy phthalocyanine, modified glassy carbon electrode for facile electrocatalysis of amitrole WOS:000455274100030 published article about REDUCED GRAPHENE OXIDE; GOLD NANOPARTICLES; NANOCOMPOSITES; OXIDATION; BEHAVIOR; TETRAAMINOPHTHALOCYANINE; NANOSHEETS; REDUCTION; NANOTUBES; OXYGEN in [Mafuwe, Peter T.; Moyo, Mambo; Mugadza, Tawanda; Shumba, Munyaradzi] Midlands State Univ, Dept Chem Technol, Sensors Lab, P Bag 9055,Senga Rd, Gweru, Zimbabwe; [Nyoni, Steven] Chinhoyi Univ Technol, Dept Chem, Chinhoyi, Zimbabwe in 2019.0, Cited 37.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Safety of 1H-1,2,4-Triazol-5-amine

Cobalt oxide nanoparticles were anchored on polyaniline-appended cobalt phthalocyanine and used to modify glassy carbon electrodes for enhanced electrocatalytic oxidation of amitrole. The modified electrodes were characterised by cyclic voltammetry, electrochemical impedance spectroscopy and scanning electron microscopy. Cyclic voltammetry, linear sweep voltammetry, chronoamperometry and differential pulse voltammetry were used to evaluate the electrocatalytic behaviour of the designed sensors. Catalytic rate constant of 6.26×10(5)M(-1)s(-1) and apparent electron transfer rate constant of 8.84×10(-3)cms(-1) were observed on CoTCPc-PANI-Co3O4NP-GCE. The adsorption equilibrium constant and Gibbs energy were 4.8×10(1)M(-1) and -12.1kJmol(-1), respectively, confirming substrate adsorption during a spontaneous reaction on the surface of the modified electrode. The limit of detection and limit of quantification were 6.61×10(-8)M and 2×10(-7)M, respectively, for the electrocatalytic detection of amitrole and only suffered 4% signal loss after repetitive ten runs in 1mM amitrole.

Safety of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Mafuwe, PT; Moyo, M; Mugadza, T; Shumba, M; Nyoni, S or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Safety of 1H-1,2,4-Triazol-5-amine. I found the field of Polymer Science very interesting. Saw the article Organotin Polymers as Antiviral Agents Including Inhibition of Zika and Vaccinia Viruses published in 2020.0, Reprint Addresses Roner, MR (corresponding author), Univ Texas Arlington, Dept Biol, Arlington, TX 76010 USA.; Carraher, CE (corresponding author), Florida Atlantic Univ, Dept Chem & Biochem, Boca Raton, FL 33431 USA.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

The ability to inhibit two important viruses is described. Two groups of polymers exhibited ability to totally inhibit the Zika virus. These polymers are derived from organotin dihalides and camphoric acid and lamivudine. This is the initial report of complete inhibition of the Zika virus by simple drugs. The ability to inhibit vaccinia virus is also reported. The inhibition of the vaccinia virus is shown by a number of organotin drugs including those also derived from lamivudine and camphoric acid and additional drugs derived from 3-amino-1,2,4-triazole, dicumarol, 4,6-diaminopyridine, alpha-cyano-4-hydroxcinnamic acid, and a variety of organotin polyethers including water soluble polymers derived from poly(ethylene glycol). All the drugs described in these studies are rapidly (< 30 s) synthesized using commercially available reactants at room temperature employing the interfacial reaction system that is employed industrially so that scale up to kilograms is relatively straight forward. Safety of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Roner, MR; Carraher, CE; Miller, L; Mosca, F; Slawek, P; Haky, JE; Frank, J or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 61-82-5. Authors Tkachenko, IG; Komykhov, SA; Gladkov, ES; Musatov, VI; Chebanov, VA; Desenko, SM in SPRINGER published article about in [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Musatov, Vladimir I.; Chebanov, Valentyn A.; Desenko, Sergey M.] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, 60 Nauky Ave, UA-61072 Kharkov, Ukraine; [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Chebanov, Valentyn A.; Desenko, Sergey M.] Kharkov Natl Univ, 4 Svobody Sq, UA-61022 Kharkov, Ukraine; [Tkachenko, Irina G.] Minist Internal Affairs Ukraine, Kharkiv Forens Sci Ctr, 32 Kovtuna St, UA-61036 Kharkov, Ukraine in 2019.0, Cited 22.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Three-component reaction of 3-amino-1H-1,2,4-triazole or 5-amino-2H-1,2,3-triazole derivatives, acetaldehyde, and 1,3-dicarbonyl compounds (acetylacetone or -keto esters) in water under microwave irradiation leads to regioselective formation of 4,7-dihydro[1,2,4]-triazolo- and 4,7-dihydro[1,2,3]triazolo[1,5-a]pyrimidines. Using ethyl 4,4,4-trifluoro-3-oxobutanoate as 1,3-dicarbonyl compound under the same conditions allows to obtain the corresponding 5-hydroxy-4,5,6,7-tetrahydro derivatives, which fail to dehydrate in the reaction medium.

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Tkachenko, IG; Komykhov, SA; Gladkov, ES; Musatov, VI; Chebanov, VA; Desenko, SM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Formula: C2H4N4. Authors Tkachenko, IG; Komykhov, SA; Gladkov, ES; Musatov, VI; Chebanov, VA; Desenko, SM in SPRINGER published article about in [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Musatov, Vladimir I.; Chebanov, Valentyn A.; Desenko, Sergey M.] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, 60 Nauky Ave, UA-61072 Kharkov, Ukraine; [Tkachenko, Irina G.; Komykhov, Sergey A.; Gladkov, Eugene S.; Chebanov, Valentyn A.; Desenko, Sergey M.] Kharkov Natl Univ, 4 Svobody Sq, UA-61022 Kharkov, Ukraine; [Tkachenko, Irina G.] Minist Internal Affairs Ukraine, Kharkiv Forens Sci Ctr, 32 Kovtuna St, UA-61036 Kharkov, Ukraine in 2019.0, Cited 22.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Three-component reaction of 3-amino-1H-1,2,4-triazole or 5-amino-2H-1,2,3-triazole derivatives, acetaldehyde, and 1,3-dicarbonyl compounds (acetylacetone or -keto esters) in water under microwave irradiation leads to regioselective formation of 4,7-dihydro[1,2,4]-triazolo- and 4,7-dihydro[1,2,3]triazolo[1,5-a]pyrimidines. Using ethyl 4,4,4-trifluoro-3-oxobutanoate as 1,3-dicarbonyl compound under the same conditions allows to obtain the corresponding 5-hydroxy-4,5,6,7-tetrahydro derivatives, which fail to dehydrate in the reaction medium.

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Tkachenko, IG; Komykhov, SA; Gladkov, ES; Musatov, VI; Chebanov, VA; Desenko, SM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Structures, Single-Molecule Magnets, and Fluorescent Properties of Four Dinuclear Lanthanide Complexes Based on 4-Azotriazolyl-3-hydroxy-2-naphthoic Acid WOS:000467351100062 published article about METAL-ORGANIC FRAMEWORKS; ION; ANISOTROPY; MAGNETIZATION; EXCHANGE; AXIALITY; BLOCKING; BEHAVIOR in [Xie, Shang-Fang; Huang, Li-Qian; Zhong, Li; Lai, Bi-Lin; Yang, Meng; Chen, Wen-Bin; Dong, Wen] Guangzhou Univ, Sch Chem & Chem Engn, Guangzhou Key Lab Environm Funct Mat & Technol, Guangzhou 510006, Guangdong, Peoples R China; [Zhang, Yi-Quan] Nanjing Normal Univ, Sch Phys Sci & Technol, Jiangsu Key Lab NSLSCS, Nanjing 210023, Jiangsu, Peoples R China in 2019.0, Cited 67.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Computed Properties of C2H4N4

Four isostructural dinuclear lanthanide complexes based on 4-azotriazolyl-3-hydroxy-2-naphthoic acid (H(3)ATNA) and 3-hydroxy-2-naphthoic acid (H(2)NA) ligands, {[Ln(2)(HATNA)(2)(HNA)(2)(H2O)(4)].6DMF} (Ln = Dy (1), Tb (2), Sm (3), Eu (4); DMF = N,N-dimethylformamide) have been prepared and characterized by X-ray diffraction crystallography, dc/ac magnetic characterization, and fluorescent spectrometry. The crystallographic data reveal dinuclear lanthanide cores of complexes 1-4, bridged by phenoxo and mu(1,3) carboxyl groups. Each nine-coordinated Ln(III) ion is located in a slightly distorted monocapped square antiprism. The ligand of H(3)ATNA displays a unique antenna effect in complex 4. Complexes 1-3 display only two ligand-centered fluorescent emissive peaks around 450 and 600 nm, and complex 4 shows four characteristic Eu(III)centered emission bands at 593, 618, 653, and 698 nm under excitation at 348 nm. Complex 1 exhibits single-molecule magnet behavior that is rationalized through ab initio calculations.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Xie, SF; Huang, LQ; Zhong, L; Lai, BL; Yang, M; Chen, WB; Zhang, YQ; Dong, W or concate me.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics