Interesting scientific research on 61-82-5

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wei, W; Gong, HY; Sheng, L; Wu, HF; Zhu, SG; Feng, L; Li, XH; You, WH or concate me.

Recommanded Product: 61-82-5. In 2021.0 CERAM INT published article about VISIBLE-LIGHT; HETEROJUNCTION; NANOSHEETS; OXIDATION; COMPOSITE; REMOVAL; GREEN; BIOI in [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Anhui Jianzhu Univ, Sch Environm & Energy Engn, Hefei 230601, Peoples R China; [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Anhui Prov Key Lab Environm Pollut Control & Reso, Hefei 230601, Peoples R China; [Wei, Wei; Gong, Haoyang; Sheng, Lin; Wu, Houfan; Zhu, Shuguang] Key Lab Water Pollut Control & Wastewater Reuse A, Hefei 230601, Peoples R China; [Feng, Li; Li, Xuhao; You, Weihong] Guangdong Univ Technol, Sch Civil & Transportat Engn, Guangzhou 510006, Guangdong, Peoples R China in 2021.0, Cited 63.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Bismuth oxyhalides (BiOX (X = Cl, Br, I) are considered to be an important p-type semiconductors in the photocatalysis applications. In particular, tetragonal BiOBr is considered as a stable photocatalyst due to its resilient absorption in the visible region with an band gap energy of 2.8 eV. In the meantime, lanthanide ions (with 3+ oxidation state) implies as conversion catalyst gained huge impact and remain a serious topic in materials chemistry. Here we synthesized upconversion photocatalyst mainly consists of BiOBr with the Er 3+ and Tb 3+ ions along with low band gap g-C3N5 for the improved photocatalytic performances. The synthesized Er3+/ Tb3+@BiOBr-g-C3N5 heterojunction was systematically characterized by XRD, and FT-IR for the confirmation of the composite and their morphology were analysed with FESEM and HR-TEM analysis which revealed that the sheets of g-C3N5 were decorated by Er3+/Tb3+ loaded BiOBr microspheres. The XPS analysis confirmed the suitable oxidation state of all the individual elements existing in the composite. As the UV-DRS analysis showed that the band gap of the Er3+/Tb3+ BiOBr-gC3N5 heterojunction was narrowed to 2.64 eV. To evaluate the photocatalytic efficiency of the synthesized g-C3N5, Er3+/Tb3+@BiOBr and Er3+/Tb3+@BiOBr-gC3N5 heterojunction under the simulated visible light irradiation source towards the aqueous sulfamethoxazole degradation. The Er3+/Tb3+@BiOBr-gC3N5 heterojunction shows maximum degradation efficiency of 94.2% after 60 min of visible light irradiation whereas the pure g-C3N5 provided about 43.8% and Er3+/Tb3+@BiOBr implies 55.2% degradation efficiency. The plausible degradation mechanism of pollutant removal was proposed.

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Wei, W; Gong, HY; Sheng, L; Wu, HF; Zhu, SG; Feng, L; Li, XH; You, WH or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

How did you first get involved in researching 1H-1,2,4-Triazol-5-amine

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ilager, D; Seo, H; Shetti, NP; Kalanur, SS; Aminabhavi, TM or concate me.

In 2020.0 SCI TOTAL ENVIRON published article about ELECTROCHEMICAL SENSOR; WO3 NANORODS; OXIDATION; NANOPARTICLES; BEHAVIOR; OXIDE; NANOTUBE; DRUG in [Ilager, Davalasab; Shetti, Nagaraj P.] KLE Inst Technol, Ctr Electrochem Sci & Mat, Dept Chem, Hubballi 580030, Karnataka, India; [Seo, Hyungtak; Kalanur, Shankara S.] Ajou Univ, Dept Mat Sci & Engn, Suwon 16499, South Korea; [Aminabhavi, Tejraj M.] SETs Coll Pharm, Pharmaceut Engn, Dharwad 580002, Karnataka, India in 2020.0, Cited 52.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. HPLC of Formula: C2H4N4

Environmental pollution by the heavy usage of pesticides has been a pandemic issue in view of the rising farming operations for increasing the crop yield to meet the requirements of food chain supply. Throughout the world, environmental pollution by the presence of pesticides, particularly the use of herbicides in large quantities to protect the crops, has posed many environmental issues. In this research, an electrochemical sensor based on tungsten oxide hydrates (WO3 center dot 0.33H(2)O) nanorod modified carbon paste electrode (CPE) was developed for the detection of herbicide, amitrole (AMT) by the cydic voltammeter. Hydrotheimally synthesized and characterized WO3 center dot 0.33H(2)O nanorod was found to be sensitive towards the detection of AMT due to its superior sensing property as the sensor showed enhanced current and catalytic property when used in phosphate buffer solution (PBS) of pH 5.0 by the cyclic voltammetric (CV) and square wave voltammetric (SWV) techniques. The influence of electro kinetic parameters viz., scan rate, pH, accumulation time and temperature with respect to AMT oxidation was studied using CV. The linearity range was in between 1.0 x 10(-8) M and 24 x 10(-5) M and limit of detection (LOD) and limit of quantification (LOQ) was calculated to be 233 nM and 7.8 nM respectively. The proposed simple method demonstrated the potential applicability to detect AMT from the soil and water samples. (C) 2020 Elsevier B.V. All rights reserved.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ilager, D; Seo, H; Shetti, NP; Kalanur, SS; Aminabhavi, TM or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Awesome Chemistry Experiments For C2H4N4

COA of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Abdelhamid, AO; Gomha, SM; El-Enany, WAMA or concate me.

COA of Formula: C2H4N4. I found the field of Chemistry very interesting. Saw the article Efficient Synthesis and Antimicrobial Evaluation of New Azolopyrimidines-Bearing Pyrazole Moiety published in 2019.0, Reprint Addresses Gomha, SM (corresponding author), Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt.; Gomha, SM (corresponding author), Islamic Univ Almadinah Almonawara, Fac Sci, Dept Chem, Almadinah Almonawara 42351, Saudi Arabia.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

Sodium salt of 3-hydroxy-1-(1-aryl-5-methylpyrazolyl)propenone derivatives was used as a precursor for synthesis of various fused azolopyrimidine ring systems as pyrazolopyrimidines, triazolopyrimidines, and pyrimidobenzimidazoles following many procedures. The identity of the prepared compounds was elucidated by their spectral data and elemental analyses. The in vitro antimicrobial activity of 13 new compounds was evaluated, and many derivatives showed good to moderate activity.

COA of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Abdelhamid, AO; Gomha, SM; El-Enany, WAMA or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Downstream Synthetic Route Of 61-82-5

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Nayak, A; Smetana, V; Mudring, AV; Rogers, RD or concate me.

HPLC of Formula: C2H4N4. In 2021.0 CRYST GROWTH DES published article about CRYSTAL-STRUCTURE; ACTINIDE; LANTHANIDE; SEPARATION; CHEMISTRY; COVALENCY; LIGAND in [Nayak, Amrita; Rogers, Robin D.] Univ Alabama, Coll Arts & Sci, Tuscaloosa, AL 35487 USA; [Smetana, Volodymyr; Mudring, Anja-Verena; Rogers, Robin D.] Stockholm Univ, Dept Mat & Environm Chem, S-10691 Stockholm, Sweden in 2021.0, Cited 36.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Continuing our investigations of ionic liquid (IL) based routes to a library of f-element/soft donor complexes which could be studied crystallographically, we have explored the dissolution of f-element salts in protic imidazole-based ILs containing only soft donors at high temperatures to drive off volatiles, including water and carboxylic or mineral acids. Here we present our results, reacting acidic and basic azoles in 1:3 or 1:1 stoichiometric compositions at elevated temperature, followed by saturation with Nd(OAc)(3)center dot xH(2)O or Ce(OAc)(3)center dot xH(2)O, which led to 13 new metal-acetate polymeric complexes identified by single-crystal X-ray diffraction. We found that the diversity in coordination modes of the simple acetate ligand that interfere with substitution of the softer N donors led to several readily crystallizable complexes forming two distinct groups with respect to f-element interaction with the ionic liquid precursors. When the acidic/basic azole ratio was 1:3, acetate and a neutral basic azole were found to be coordinated to the metal centers but no water, although in one case (2) water was observed in the secondary coordination sphere: [Ce(mu(2)-OAc)(3)(C(1)im)](n) (1, C(1)im = 1-methylimidazole), [Nd(mu(2)-(OAc)(3)(C(1)im)](n)center dot nH(2)O (2), [Ce(mu(2)-OAc)(3)(C(2)im)](n) (3, C(2)im = 1-ethylimidazole), [Ln(mu(2)-OAc)(3)DMF](n) (Ln = Nd (4), Ce (5); dimethylformamide (DMF) was substituted for the azole mixture), and [Nd(mu(2)-OAc)(3)(C(4)im)](n) (6, C(4)im = 1-butylimidazole). However, when the stoichiometric ratio was 1:1, water was always observed coordinated to the metal ions with the acidic azole included in the structure as a solvate or cocrystal, despite a higher reaction temperature: [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(1,2,3-Taz) (7,1,2,3-Taz = 1,2,3-triazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(4,5-DCim) (Ln = Nd (8), Ce (9), 4,5-DCim = 4,5-dicyanoimidazole), [Ln(mu(2)-OAc)(3)(OH2)](n)center dot n(3,5-diNH(2)-1,2,4-Taz) (Ln = Nd (10), Ce (11), 3,5diNH(2)-1,2,4-Taz = 3,5-diamino-1,2,4-triazole), [Ce(mu(2)-OAc)(3)(OH2)](n)center dot n(3-NH2-1,2,4-Taz) (12, 3-NH2-1,2,4-Taz = 3-amino-1,2,4-triazole), and [Nd(mu(2)-OAc)(3)(OH2)](n)center dot n(5-NH2-Tz) (13, 5-NH2-Tz = 5-aminotetrazole). All of the compounds retain the Ln:OAc- ratio of 1:3 and form 1D polymeric chains; however, they exhibit a variety of coordination modes affecting the degree of chain condensation. The isolation of both hydrated and anhydrous products revealed different abilities of the investigated soft N-donors to compete with O-donors finding their place in the coordination sphere of the lanthanide or in the crystal lattice.

HPLC of Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Nayak, A; Smetana, V; Mudring, AV; Rogers, RD or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Final Thoughts on Chemistry for 61-82-5

Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Antil, B; Ranjan, R; Gopinath, CS; Deka, S or concate me.

Recommanded Product: 1H-1,2,4-Triazol-5-amine. In 2020.0 J MATER CHEM A published article about GRAPHITIC CARBON NITRIDE; PHOTOCATALYTIC H-2 EVOLUTION; POLYMERIC PHOTOCATALYST; ELECTRON-TRANSFER; SURFACE-AREA; NANOSHEETS; WATER; NANOPARTICLES; G-C3N4; DOTS in [Antil, Bindu; Deka, Sasanka] Univ Delhi, Dept Chem, Nanochem Lab, North Campus, Delhi 110007, India; [Ranjan, Ravi; Gopinath, Chinnakonda S.] CSIR, Catalysis & Inorgan Chem Div, Natl Chem Lab, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India; [Ranjan, Ravi; Gopinath, Chinnakonda S.] CSIR, Acad Sci & Innovat Res AcSIR, Natl Chem Lab, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India in 2020.0, Cited 47.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

It is desirable yet challenging to synthesize a highly ordered holey carbon nitride material with excess nitrogen atoms for a sustainable solar H(2)evolution. Herein, we report the development of directed highly ordered nitrogen-rich honeycomb-like mesoporous carbon nitride nanosheets by using a novel synthetic approach for this purpose. The unique formation route, surface structure and charge carrier dynamics of the two dimensional holey nanosheets are comprehensively monitored and confirmed by SAXS, HRTEM, AFM, BET, XPS and TRPL analyses. Non-stoichiometric high nitrogen content mesoporous nanosheets with the final stoichiometry of g-C(3)N(4.5)acquiring a high specific surface area (382 m(2)g(-1)), remarkable pore size (7.2 nm) and sheet thickness similar to 5-6 nm are realized in this first report. This elegant material possesses unique low band-gap energy (2.42 eV). Remarkably, the as-synthesized g-C(3)N(4.5)NSs exhibit a record high photocatalytic H(2)evolution rate of 8180 mu mol g(-1)h(-1)under the present light irradiation (420 <=lambda <= 510 nm) condition. The apparent quantum efficiency is found to be as high as 27.14% at 420 nm and retains its photocatalytic activity for longer consecutive catalytic cycles. Bigger pore size and pore volume, and thin walls leading to shortening of the path length of exciton pairs, efficient charge separation and the prolonged average life time of the charge carriers, and lone electron pairs associated with the excess nitrogen content are found to be the reasons behind the excellent visible light driven water splitting reaction. Recommanded Product: 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Antil, B; Ranjan, R; Gopinath, CS; Deka, S or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An update on the compound challenge: 61-82-5

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhang, QM; Li, D; Cao, XK; Gu, HX; Deng, W or concate me.

Zhang, QM; Li, D; Cao, XK; Gu, HX; Deng, W in [Zhang, Qinmei; Li, Dan; Cao, Xiukai; Deng, Wei] Shanghai Inst Technol, Sch Chem & Environm Engn, 100 Haiquan Rd, Shanghai 201418, Peoples R China; [Gu, Haixin] Shanghai Fire Res Inst MEM, 918 Minjing Rd, Shanghai 200438, Peoples R China published Self-Assembled Microgels Arrays for Electrostatic Concentration and Surface-Enhanced Raman Spectroscopy Detection of Charged Pesticides in Seawater in 2019.0, Cited 36.0. Quality Control of 1H-1,2,4-Triazol-5-amine. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

Development of flexible surface-enhanced Raman spectroscopy (SERS) substrate with controllable hot spots has spurred increasing interest because of its unique structure and plasmonic properties. Here, charged poly(vinyl alcohol) microgels containing silver nanoparticles are developed by using microfluidic emulsification to produce a smart SERS sensor with charge screening and signals amplification. Importantly, this charged microgel enables the selective concentration of counter-charged molecules and induces the formation of assembled arrays at an immiscible liquid-liquid interface because of the electrostatic interaction. The SERS-active microgels arrays possess controllable structures and facilitate on-site determination of charged pesticides with an enhancement factor of 5.0 x 10(5). Such nanostructures present the ease of assembly, stability, and reproducibility which allow multiplex detection of analytes at aqueous and organic phases without any pretreatment of complex matrix samples. The interfacial sensing platform for on-site SERS analysis of charged pesticides will open vast possibilities for a wide range of in-field applications.

Quality Control of 1H-1,2,4-Triazol-5-amine. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Zhang, QM; Li, D; Cao, XK; Gu, HX; Deng, W or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

What advice would you give a new faculty member or graduate student interested in a career 61-82-5

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ilager, D; Seo, H; Shetti, NP; Kalanur, SS or concate me.

Computed Properties of C2H4N4. I found the field of Engineering very interesting. Saw the article CTAB modified Fe-WO3 as an electrochemical detector of amitrole by catalytic oxidation published in 2020.0, Reprint Addresses Shetti, NP (corresponding author), KLE Inst Technol, Ctr Electrochem Sci & Mat, Dept Chem, Hubballi 580027, Karnataka, India.; Kalanur, SS (corresponding author), Ajou Univ, Dept Mat Sci & Engn, Suwon 16499, South Korea.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine.

The increasing health risk associated with the exposure to mutagenic, teratogenic and carcinogenic herbicide the environment has encouraged a significant interest towards the development of rapid and cheaper detection technologies for the accurate quantification. The present work involves the exploitation of catalytic oxidation herbicide, amitrole (AMT) at iron doped tungsten oxide (Fe-WO3) nanoparticles and cationic surfactant cetyltrimethylammonium bromide (CTAB) based carbon paste electrode for the sensitive quantification. The working electrode assembly of Fe-WO3/CTAB causes the catalytic oxidation via faster electron transfer compared to bare electrode. Furthermore, the physiochemical properties and thermodynamic properties of AMT were explored. Under the optimized conditions, the modified sensor exhibits good linear detection range (5.0 x 10(-8) M to 8.0 x 10(-5) M), lower limit of detection (0.82 nM) and limit of quantification (2.82 nM) by square wave voltammetric (SWV) technique. Hence, developed senor showed an intensification of peak current of AMT with significant sensitivity, selectivity and reproducibility for AMT analysis and received acceptable results indicates the application of sensors for the analysis of AMT in water as well as soil samples.

Computed Properties of C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Ilager, D; Seo, H; Shetti, NP; Kalanur, SS or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Now Is The Time For You To Know The Truth About 61-82-5

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Gol, RM; Khatri, TT; Barot, VM or concate me.. Product Details of 61-82-5

An article Facile Regioselective On-Water Synthesis of 4,7-Dihydropyrazolo[1,5-a]Pyrimidines and 4,7-Dihydro[1,2,4]Triazolo[1,5-a]Pyrimidines WOS:000467059700011 published article about DESIGN; INHIBITOR; POTENT; 5-AMINOPYRAZOLE; ANAGLIPTIN; DINACICLIB; ESSRAMYCIN; PYRAZOLE in [Gol, Ravindra M.; Barot, Vijaykumar M.] Smt SM Panchal Sci Coll, Dept Chem, Talod 383215, Gujarat, India; [Khatri, Taslimahemad T.] Govt Sci Coll, Dept Chem, Chikhli 396521, Gujarat, India in 2019.0, Cited 50.0. Product Details of 61-82-5. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5

Efficient and regioselective on-water synthesis of variously substituted 5-amino-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carbonitriles and 5-amino-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles using 1,8-diazabicyclo[5.4.0]undec-7-ene as catalyst has been demonstrated. The reaction of 2-benzylidenemalononitriles and 3-aryl-1H-pyrazol-5-amines or 1H-1,2,4-triazol-5-amine allows to obtain the respective pyrazolo[1,5-a]pyrimidines and [1,2,4]triazolo[1,5-a]pyrimidines in high yields up to 93%. Main advantages of the developed synthetic protocol are application of water as environmentally friendly solvent, short reaction times, simple workup procedure that often does not require further purification of products, and broad substrate scope.

About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Gol, RM; Khatri, TT; Barot, VM or concate me.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

More research is needed about C2H4N4

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact El Sayed, MT; Sarhan, AE; Ahmed, E; Khattab, RR; Elnaggar, M; El-Messery, SM; Shaldam, MA; Hassan, GS or concate me.

Formula: C2H4N4. In 2020.0 CHEMISTRYSELECT published article about TRANSITION-METAL COMPOUNDS; DENSITY-FUNCTIONAL THEORY; MOLECULAR-STRUCTURES; DOCKING; MOLYBDENUM; INDOLES; MANNICH; BONDS in [El Sayed, Mardia T.] Natl Res Ctr, Chem Ind Res Div, Appl Organ Chem Dept, Dokki 12311, Egypt; [Sarhan, Alaadin E.] Natl Res Ctr, Pharmaceut Div, Therapeut Chem Dept, Dokki 12311, Egypt; [Ahmed, Entsar] Al Azhar Univ, Chem Dept, Fac Sci, Girls Branch, Cairo, Egypt; [Khattab, Reham R.] Natl Res Ctr, Chem Ind Res Div, Photochem Dept, Dokki 12311, Egypt; [Elnaggar, Mohamed] Univ Sharjah, Fac Sci, Chem Dept, Sharjah 27272, U Arab Emirates; [El-Messery, Shahenda M.] Mansoura Univ, Fac Pharm, Dept Organ Pharmaceut Chem, POB 35516, Mansoura, Egypt; [Shaldam, Moataz A.] Kafrelsheikh Univ, Fac Pharm, Dept Pharmaceut Chem, Kafr Al Sheikh 33516, Egypt; [Hassan, Ghada S.] Mansoura Univ, Fac Pharm, Dept Med Chem, Mansoura 35516, Egypt in 2020.0, Cited 39.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In the present investigation, some novel nitro Mannich bases derived from Michael type addition of activated nitro olefin, beta-nitrostyrene with various amines either primary or secondary including some amino sugars were designed and synthesized. The produced Mannich bases have been full characterized through different spectroscopic techniques. Antimicrobial evaluation has been performed against the Gram positive S. aureus and methicillin-resistant S. aurues (MRSA) infections. 5 of the synthesized compounds represent the best candidates in the biological screening, they have exhibited good activity with MIC values range from 100 to 250 mu g/ml. The active agents have been tested for pyruvate kinase inhibition activity with % of inhibition range from 30 to 79 % with IC50 in a nano molar range. They also exhibited significant Pyruvate kinase inhibition in nanomolar range with IC50 of 1066, 662, 1887, 418 and 1128 ng/ml, respectively (versus 196 ng/ml for AZD7545). Molecular docking calculations for active agents were performed. A complete conformational analysis molecular modeling utilizing Gaussian 09 program (HF/DFT) was used to verify the mode of bonding through the optimized geometries as well as essential quantum parameters were calculated using frontier energies (EHOMO & ELUMO) for the active candidates indicating the overall stability of the structure.

Formula: C2H4N4. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact El Sayed, MT; Sarhan, AE; Ahmed, E; Khattab, RR; Elnaggar, M; El-Messery, SM; Shaldam, MA; Hassan, GS or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

What kind of challenge would you like to see in a future of compound:61-82-5

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Voitekhovich, SV; Grigoriev, YV; Lyakhov, AS; Matulis, VE; Ivashkevich, LS; Bogomyakov, AS; Lavrenova, LG; Ivashkevich, OA or concate me.

Recently I am researching about MAGNETIC-PROPERTIES; CRYSTAL-STRUCTURE; COORDINATION POLYMERS; CHAINS; LIGANDS; PROTON; THERMODYNAMICS; PERFORMANCE; TETRAZOLES; STRATEGY, Saw an article supported by the Belarusian Republican Foundation for Fundamental Research [X1 6P-009, X18P-043]; Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR) [18-53-00006 Bel_a]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Voitekhovich, SV; Grigoriev, YV; Lyakhov, AS; Matulis, VE; Ivashkevich, LS; Bogomyakov, AS; Lavrenova, LG; Ivashkevich, OA. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine. Recommanded Product: 61-82-5

1-(1,2,4-Triazol-3-yl)-1H-tetrazole (trt) and 1-(1-tert-butyl-1,2,4-triazol-3-yl)-1H-tetrazole (btrt) were synthesized by heterocyclization of corresponding amines with triethyl orthoformate and sodium azide. The interaction of trt with copper(II) chloride in ethanol in the presence of hydrochloric acid was found to result in 10 coordination polymer [CuCl2(trt)(H2O)](n)center dot nH(2)O. N-tert-butylated ligand btrt reacts with the copper salt in ethanol giving 2D coordination polymer [CuCl2(btrt)](n). Tetrazole ring-opening reaction with the formation of [CuCl2(3-amino-1,2,4-triazolium)(2)][CuCl4]center dot 2H(2)O was observed in the interaction of trt with copper(II) chloride in aqueous hydrochloric acid. The temperature-dependent magnetic susceptibility measurements of [CuCl2(btrt)](n) revealed that the copper(II) ions were weakly ferromagnetically coupled showing a coupling constant J of 1.2 cm(-1). (C) 2019 Elsevier Ltd. All rights reserved.

Recommanded Product: 61-82-5. About 1H-1,2,4-Triazol-5-amine, If you have any questions, you can contact Voitekhovich, SV; Grigoriev, YV; Lyakhov, AS; Matulis, VE; Ivashkevich, LS; Bogomyakov, AS; Lavrenova, LG; Ivashkevich, OA or concate me.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics