Category: 288-36-8

《Gas-phase UV absorption spectra and OH-oxidation kinetics of 1H-1,2,3-triazole and pyrazole》 was written by Samir, Brahim; Kalalian, Carmen; Roth, Estelle; Salghi, Rachid; Chakir, Abdelkhaleq. Safety of 1H-1,2,3-TriazoleThis research focused ontriazole pyrazole oxidation kinetics mechanism gas phase UV spectra. The article conveys some information:

In this work, we report the gas phase UV absorption spectra and the kinetics of the OH-oxidation of 1H-1,2,3-triazole and pyrazole. UV spectra were determined between 200 and 250 nm, at 350 ± 2 K and at pressures between 0.09 and 0.3 Torr. The reported maximal UV absorption cross sections are (cm2 per mol.): σ206 nm, 1H-1H-1,2,3-triazole = 2.04 x 10-18 and σ203 nm, pyrazole = 5.44 x 10-18. The very low absorption capacity of these compounds beyond 240 nm indicates that their atm. photodissociation is negligible. The OH-oxidation of these species was performed in an atm. simulation chamber coupled to an FTIR spectrometer and to a GC/MS over the temperature range 298-357 K and at atm. pressure. Experiments were conducted in relative mode using benzaldehyde, trans-2-hexenal and heptane as references The obtained rate constants at 298 K were (x10-11 cm3 per mol. per s): k(OH + 1H-1,2,3-triazole) = 2.16 ± 0.41; k(OH + pyrazole) = 2.94 ± 0.42. These results were compared to those available in the literature and discussed in terms of structure-reactivity and temperature dependency. Their tropospheric lifetimes with respect to reaction with OH radicals were then estimated In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole(cas: 288-36-8Safety of 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Safety of 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

《Electrochemical Decarboxylative N-Alkylation of Heterocycles》 was written by Sheng, Tao; Zhang, Hai-Jun; Shang, Ming; He, Chi; Vantourout, Julien. C.; Baran, Phil. S.. Computed Properties of C2H3N3 And the article was included in Organic Letters in 2020. The article conveys some information:

An operationally simple method to employ nonactivated carboxylic acids as alkylating agents in the N-alkylation of heterocycles is reported through an electrochem. driven anodic decarboxylative process. A wide substrate scope across a range of heterocycles is demonstrated along with a series of applications that significantly reduce the step count required to access such medicinally relevant structures. In the experiment, the researchers used 1H-1,2,3-Triazole(cas: 288-36-8Computed Properties of C2H3N3)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Computed Properties of C2H3N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

《ab-initio study of hydrogen bond networks in 1,2,3-triazole phases》 was written by Peschel, Christopher; Dressler, Christian; Sebastiani, Daniel. Reference of 1H-1,2,3-TriazoleThis research focused ontriazole hydrogen bond; ab-initio molecular dynamics; crystal structure; diffusion coefficient; fuel cell; hydrogen bond network; pi-pi-stacking; proton conductivity; tautomerism. The article conveys some information:

The research in storage and conversion of energy is an everlasting process. The use of fuel cells is very tempting but up to now there are still several conceptual challenges to overcome. Especially, the requirement of liquid water causes difficulties due to the temperature limit. Therefore, imidazoles and triazoles are increasingly investigated in a manifold of exptl. and theor. publications as they are both very promising in overcoming this problem. Recently, triazoles were found to be superior to imidazoles in proton conduction. An ab-initio mol. dynamics simulation of pure triazole phases for investigating the behavior of both tautomer species of the triazole mol. has never been done. In this work, we investigate the structural and dynamical properties of two different solid phases and the liquid phase at two different temperatures We are able to show how the distinct tautomers contribute to the mechanism of proton conduction, to compute dynamical properties of the four systems and to suggest a mechanism of reorientation in solid phase. The results came from multiple reactions, including the reaction of 1H-1,2,3-Triazole(cas: 288-36-8Reference of 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Reference of 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

COA of Formula: C2H3N3In 2020 ,《Effect of Pore Size on the Separation of Ethylene from Ethane in Three Isostructural Metal Azolate Frameworks》 appeared in Inorganic Chemistry. The author of the article were Jiang, Xue; Zhang, Tao; Cao, Jian-Wei; Zhao, Chong-Kai; Yang, Rong; Zhang, Qiu-Yu; Chen, Kai-Jie. The article conveys some information:

The pore-size effect on ethane adsorption and ethane/ethylene separation in three isostructural metal azolate frameworks (MAF-123-Mn/Zn/Cu) were thoroughly investigated. MAF-123-Mn/Zn/Cu were synthesized by the solvothermal method on a gram scale. Decreasing the pore size from 6.1 to 4.9 Å leads to an increase in the ethane adsorption energy from 23 to 27.5 kJ mol-1 and further ethane/ethylene separation efficiency. Mol. simulations revealed that a shorter ethane-framework interaction distance in MAF-123-Zn than that in MAF-123-Mn is responsible for the increased adsorption energy. Dynamic breakthrough experiments manifest that these metal azolate frameworks can effectively produce high-purity ethylene from ethane in one adsorption step. Exquisite pore-size control by metal alternation was achieved in three metal azolate frameworks for enhanced ethane/ethylene separation The experimental part of the paper was very detailed, including the reaction process of 1H-1,2,3-Triazole(cas: 288-36-8COA of Formula: C2H3N3)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties COA of Formula: C2H3N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

《Organophotoredox-Catalyzed Direct C-H Amination of 2H-Indazoles with Amines》 was published in Organic Letters in 2020. These research results belong to Neogi, Sukanya; Ghosh, Asim Kumar; Majhi, Koushik; Samanta, Sadhanendu; Kibriya, Golam; Hajra, Alakananda. Application In Synthesis of 1H-1,2,3-Triazole The article mentions the following:

A general and practical method for the direct C-H amination of 2H-indazoles with a series of amines including aliphatic primary amines, secondary amines, azoles and sulfoximines via organophotoredox-catalyzed oxidative coupling to gave aryl(amine/imino)indazols I [R1 = 4-Me, 3-OMe, 4-i-Pr, etc.; R2 = H, 5-F, 5-Cl, 5-OMe; R3 = NH2, pyrazol-1-yl, 1-piperidyl, etc.] was disclosed at room temperature under ambient air conditions. Addnl., this protocol was used for free aminated 2H-indazole I [R1 = Me; R2 = H, 5-Cl; R3 = NH2] synthesis. A mechanistic study revealed that a single electron transfer (SET) pathway might be involved in this reaction.1H-1,2,3-Triazole(cas: 288-36-8Application In Synthesis of 1H-1,2,3-Triazole) was used in this study.

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Application In Synthesis of 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019,Organic Letters included an article by Wang, Jing-Hao; Lei, Tao; Nan, Xiao-Lei; Wu, Hao-Lin; Li, Xu-Bing; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu. Recommanded Product: 1H-1,2,3-Triazole. The article was titled 《Regioselective Ortho Amination of an Aromatic C-H Bond by Trifluoroacetic Acid via Electrochemistry》. The information in the text is summarized as follows:

Aryl ethers such as anisole underwent regioselective electrochem. ortho-amination/arylation with pyrazoles and aromatic nitrogen heterocycles mediated by trifluoroacetic acid (TFA) in an undivided cell to give arylpyrazoles such as 1-(2-methoxyphenyl)pyrazole and arylated nitrogen heterocycles. The results came from multiple reactions, including the reaction of 1H-1,2,3-Triazole(cas: 288-36-8Recommanded Product: 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Recommanded Product: 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Related Products of 288-36-8In 2020 ,《Imidazole-Selective Alkyne Hydroamination under Physiological Conditions》 appeared in Organic Letters. The author of the article were Kang, Hyung-Joon; Lee, Joon-Ho; Kim, Dong-Hyun; Cho, Cheon-Gyu. The article conveys some information:

Imidazole-selective intermol. hydroamination reaction has been discovered. This unprecedented additive-free addition reaction proceeds in an exclusively regioselective and stereoselective manner with high atom economy under extremely mild reaction conditions. In the experiment, the researchers used many compounds, for example, 1H-1,2,3-Triazole(cas: 288-36-8Related Products of 288-36-8)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Related Products of 288-36-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2022,Salinas-Torres, Angelica; Portilla, Jaime; Rojas, Hugo; Becerra, Diana; Castillo, Juan-Carlos published an article in Molbank. The title of the article was 《Synthesis, Spectroscopic Analysis, and In Vitro Anticancer Evaluation of 2-(Phenylsulfonyl)-2H-1,2,3-triazole》.Application of 288-36-8 The author mentioned the following in the article:

The 1,2,3-triazole derivatives containing the sulfonyl group have proved their biol. importance in medicinal chem. and drug design. In this sense, the regioselective synthesis of 2-(phenylsulfonyl)-2H-1,2,3-triazole in good yield through a classical sulfonamidation reaction of 1H-1,2,3-triazole with benzenesulfonyl chloride in dichloromethane using a slight excess of triethylamine at 20° for 3 h is described. This procedure is distinguished by its short reaction time, high yield, excellent regioselectivity, clean reaction profile, and operational simplicity. The sulfonamide exhibited moderate activity against UO-31 renal, SNB-75 central nervous system, HCT-116 colon, and BT-549 breast cancer cell lines, with growth inhibition percentages (GI%) ranging from 10.83% to 17.64%. The experimental part of the paper was very detailed, including the reaction process of 1H-1,2,3-Triazole(cas: 288-36-8Application of 288-36-8)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Application of 288-36-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019,Organic Letters included an article by Roshandel, Sahar; Lunn, Maiko J.; Rasul, Golam; Muthiah Ravinson, Daniel Sylvinson; Suri, Suresh C.; Prakash, G. K. Surya. SDS of cas: 288-36-8. The article was titled 《Catalyst-Free Regioselective N2 Arylation of 1,2,3-Triazoles Using Diaryl Iodonium Salts》. The information in the text is summarized as follows:

The widespread application of 1,2,3-triazoles in pharmaceuticals has resulted in substantial interest toward developing efficient postmodification methods. Whereas there are many postmodification methods available to obtain N1-substituted 1,2,3-triazoles, developing a selective and convenient protocol to synthesize N2-aryl-1,2,3-triazoles has been challenging. A catalyst-free and regioselective method to access N2-aryl-1,2,3-triazoles in good to excellent yields (66-97%), is reported. This scalable postmodification protocol is effective for a wide range of substrates. The experimental process involved the reaction of 1H-1,2,3-Triazole(cas: 288-36-8SDS of cas: 288-36-8)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties SDS of cas: 288-36-8

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Recommanded Product: 1H-1,2,3-TriazoleIn 2020 ,《Access to α-Pyrazole and α-Triazole Derivatives of Ketones from Oxidative Heteroarylation of Silyl Enolethers》 appeared in Organic Letters. The author of the article were Dhanju, Sandeep; Caravana, Aidan C.; Thomson, Regan J.. The article conveys some information:

The synthesis of α-pyrazole and α-triazole derivatives of ketones by the ceric ammonium nitrate-mediated oxidative coupling of enolsilanes with heteroarenes is reported. The reaction proceeds under mild reaction conditions to provide a diversity of products, including sterically hindered fully substituted derivatives The results came from multiple reactions, including the reaction of 1H-1,2,3-Triazole(cas: 288-36-8Recommanded Product: 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Recommanded Product: 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics