Akula, Hari K.’s team published research in Organic & Biomolecular Chemistry in 2017 | CAS: 56602-33-6

((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.Synthetic Route of C12H22F6N6OP2

In 2017,Akula, Hari K.; Kokatla, Hariprasad; Andrei, Graciela; Snoeck, Robert; Schols, Dominique; Balzarini, Jan; Yang, Lijia; Lakshman, Mahesh K. published 《Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products [Erratum to document cited in CA166:166082]》.Organic & Biomolecular Chemistry published the findings.Synthetic Route of C12H22F6N6OP2 The information in the text is summarized as follows:

Correction for ′Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biol. evaluations of the products′ by Hari K. Akula, et al., Organic Biomol. Chem., 2017, DOI: 10.1039/c6ob02334g. The experimental part of the paper was very detailed, including the reaction process of ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6Synthetic Route of C12H22F6N6OP2)

((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is a peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.Synthetic Route of C12H22F6N6OP2

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics