Wang, Yanwei published the artcileSynthesis and antifungal activity of novel triazole compounds containing piperazine moiety, Name: 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, the publication is Molecules (2014), 19(8), 11333-11340, 8 pp., database is CAplus and MEDLINE.
Design and synthesis of triazole library antifungal agents having piperazine side chains, analogs to fluconazole I (R = 2-F, 3-F, 4-F, etc.) were documented. The synthesis highlighted utilization of the click chem. on the basis of the active site of the cytochrome P 450 14α-demethylase (CYP51). The influences of piperazine moiety on in vitro antifungal activities of all the target compounds were evaluated against eight human pathogenic fungi.
Molecules published new progress about 86386-77-8. 86386-77-8 belongs to triazoles, auxiliary class Epoxides,Triazole,Fluoride,Salt,Sulfonic acid,Benzene, name is 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate, and the molecular formula is C24H26ClNO4, Name: 1-((2-(2,4-Difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole methanesulfonate.
Referemce:
https://en.wikipedia.org/wiki/1,2,3-Triazole,
Triazoles – an overview | ScienceDirect Topics