Reference of 626248-56-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 626248-56-4 name is 3-(2H-1,2,3-Triazol-2-yl)aniline, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
The 4,6-dichloro-2 – (methyl mercapto) pyrimidine-5-a nitrile (4.0g, 18mmol), 3 – (2H-1, 2, 3-triazol-2-yl) aniline (2.9g, 18mmol) and sodium acetate (3.0g, 36mmol) dissolved in 100 ml ethanol, stirring at room temperature the reaction solution 5h, filtering, the filter cake washing with ethanol 5.0g yellow solid, yield 80%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-(2H-1,2,3-Triazol-2-yl)aniline, and friends who are interested can also refer to it.
Reference:
Patent; KBP Biosciences Co., Ltd.; Wang, Aichen; Qian, Linyi; (29 pag.)CN104640863; (2016); B;,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics