Month: October 2022

Lee, Anna; Scheidt, Karl A. published an article in 2015, the title of the article was N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins.Name: (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate And the article contains the following content:

A highly efficient asym. formal [4+2] annulation for the synthesis of dihydrocoumarins has been developed via an in situ activated NHC catalysis. Both electrophilic and nucleophilic species are generated in situ simultaneously whereby acyl imidazoles facilitated rapid formation of an NHC-enolate intermediate to afford the [4+2] dihydrocoumarin adducts. The experimental process involved the reaction of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate(cas: 1469801-67-9).Name: (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate

The Article related to nitrogen heterocyclic carbene catalyzed enantioselective formal annulation addition, dihydrocoumarin adduct preparation in situ activated nhc catalyst, acylimidazole facilitated nhc enolate intermediate formation, in situ generated electrophile nucleophile dihydrocoumarin preparation and other aspects.Name: (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Vorona, Svetlana V.; Zevatskii, Yuri E.; Myznikov, Leonid V. published an article in 2019, the title of the article was Zinc (II) Chloride as Phase Transfer Catalyst and as Catalyst of Cycloaddition Azide Ion to Heterocumulenes and Terminal Alkynes in Organic Solvents.Name: 4-(p-Tolyl)-1H-1,2,3-triazole And the article contains the following content:

The system of NaN3-ZnCl2 in organic solvents was effective for azide ion cycloaddition to heterocumulenes and terminal alkynes. The reaction proceeded readily in the case of heterocumulenes, so these transformations fall into the category of click reactions. The study on the reaction mechanism showed that role of zinc salt consists in transferring azide ion to the organic phase and decreasing the energy barrier of nucleophilic addition of azide ion to the unsaturated substrate. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Name: 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to isothiocyanate sodium azide zinc chloride catalyst cycloaddition, thiotetrazole preparation, carbodiimide sodium azide zinc chloride catalyst cycloaddition, aminotetrazole preparation, terminal alkyne sodium azide zinc chloride catalyst regioselective cycloaddition, triazole preparation and other aspects.Name: 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On January 14, 2015, Goodman, C. Guy; Walker, Morgan M.; Johnson, Jeffrey S. published an article.Computed Properties of 1469801-67-9 The title of the article was Enantioconvergent Synthesis of Functionalized γ-Butyrolactones via (3 + 2)-Annulation. And the article contained the following:

A dynamic kinetic resolution of β-halo α-keto esters, RO2CC(:O)CHXR’ [R = Me, Bu-t, R’ = CH2Ph, X = Cl; R = Bu-t, R’ = Ph, Me, CH2CH2Me, CH2CCSiMe3, (CH2)3OCH2Ph; R = Bu-t, R’ = Ph, X = F] in an asym. homoenolate reaction is described. A chiral N-hetereocyclic carbene catalyzes the a3 → d3-umpolung addition of α,β-enals to racemic α-keto esters, forming γ-butyrolactones I [R1 = Ph, C6H4OMe-4, C6H4Cl-4, C6H4Me-4, C6H4Me-3, thien-2-yl, furan-2-yl, CH:CHPh-(E), CO3Et] and II [R2 = Ph, Me, CH2CH:CH2, CH2CCSiMe3, (CH2)3OCH2Ph, X = Cl; R = Ph, X = F] with three contiguous stereocenters. The addition occurs with high regio-, diastereo-, and enantiocontrol. This methodol. constitutes an intermol. DKR process to set three stereocenters during the key bond forming event. The experimental process involved the reaction of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate(cas: 1469801-67-9).Computed Properties of 1469801-67-9

The Article related to butyrolactone gamma derivative enantioconvergent annulation synthesis, halo keto ester dynamic kinetic resolution asym homoenolate reaction, alkenal annulation halo keto ester hetereocyclic carbene catalyst, regioselective annulation halo keto ester alkenal hetereocyclic carbene catalyst and other aspects.Computed Properties of 1469801-67-9

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On March 3, 2010, Grimster, Neil; Zhang, Li; Fokin, Valery V. published an article.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole The title of the article was Synthesis and Reactivity of Rhodium(II) N-Triflyl Azavinyl Carbenes. And the article contained the following:

Highly reactive rhodium(II) N-trifluoromethylsulfonyl azavinyl carbenes are formed in situ from NH-1,2,3-triazoles, triflic anhydride, and rhodium carboxylates. They rapidly and selectively react with olefins, providing cyclopropane carboxaldehydes and 2,3-dihydropyrroles in generally excellent yields and high enantio- and diastereoselectivity. The experimental process involved the reaction of 4-(p-Tolyl)-1H-1,2,3-triazole(cas: 5301-96-2).Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

The Article related to triazole triflic anhydride chiral rhodium carboxylate catalyst, rhodium azavinyl carbene triflyl derivative formation alkene cyclopropanation, cyclopropane carboxaldehyde stereoselective preparation, alkene rhodium triflyl azavinyl carbene dipolar cycloaddition, dihydropyrrole derivative regioselective preparation and other aspects.Reference of 4-(p-Tolyl)-1H-1,2,3-triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

On September 21, 2018, Sun, Jun; Mou, Chengli; Wang, Zhongyao; He, Fangcheng; Wu, Jian; Chi, Yonggui Robin published an article.Quality Control of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate The title of the article was Carbene-Catalyzed [4 + 2] Cycloadditions of Vinyl Enolate and (in Situ Generated) Imines for Enantioselective Synthesis of Quaternary α-Amino Phosphonates. And the article contained the following:

A carbene-catalyzed enantioselective addition of enals to five-membered cyclic imines is developed. The reaction gives chiral quaternary α-amino phosphonates bearing tetrasubstituted C centers with excellent enantioselectivities. The imine substrates can be generated in situ from the corresponding amines under an oxidative condition that is compatible with the carbene catalysis. Thus, a 1-pot cross-dehydrogenative-coupling (CDC) reaction between enals and amines is also realized with high enantioselectivity remaining. The method provides quick enantioselective access to amino phosphonates with potential applications in medicines and pesticides. The experimental process involved the reaction of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate(cas: 1469801-67-9).Quality Control of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate

The Article related to carbene catalyzed cycloaddition vinyl enolate imine, ketiminophosphonate cyclic preparation cycloaddition vinyl enolate carbene catalyst, quaternary alpha amino phosphonate preparation, crystal structure benzoisothiazolopyridinylphosphonate quaternary alpha amino phosphonate, mol structure benzoisothiazolopyridinylphosphonate quaternary alpha amino phosphonate and other aspects.Quality Control of (R)-5-Benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Application In Synthesis of 1H-1,2,3-TriazoleIn 2020 ,《Identification of the Electronic and Structural Dynamics of Catalytic Centers in Single-Fe-Atom Material》 was published in Chem. The article was written by Li, Xuning; Cao, Chang-Su; Hung, Sung-Fu; Lu, Ying-Rui; Cai, Weizheng; Rykov, Alexandre I.; Miao, Shu; Xi, Shibo; Yang, Hongbin; Hu, Zehua; Wang, Junhu; Zhao, Jiyong; Alp, Esen Ercan; Xu, Wei; Chan, Ting-Shan; Chen, Haoming; Xiong, Qihua; Xiao, Hai; Huang, Yanqiang; Li, Jun; Zhang, Tao; Liu, Bin. The article contains the following contents:

The lack of model single-atom catalysts (SACs) and at.-resolution operando spectroscopic techniques greatly limits our comprehension of the nature of catalysis. Herein, based on the designed model single-Fe-atom catalysts with well-controlled microenvironments, we have explored the exact structure of catalytic centers and provided insights into a spin-crossover-involved mechanism for oxygen reduction reaction (ORR) using operando Raman, X-ray absorption spectroscopies, and the developed operando57Fe Mossbauer spectroscopy. In combination with theor. studies, the N-FeN4C10 moiety is evidenced as a more active site for ORR. Moreover, the potential-relevant dynamic cycles of both geometric structure and electronic configuration of reactive single-Fe-atom moieties are evidenced via capturing the peroxido (*O-2) and hydroxyl (*OH-) intermediates under in situ ORR conditions. We anticipate that the integration of operando techniques and SACs in this work shall shed some light on the electronic-level insight into the catalytic centers and underlying reaction mechanism. In the experimental materials used by the author, we found 1H-1,2,3-Triazole(cas: 288-36-8Application In Synthesis of 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Application In Synthesis of 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2022,Wu, Yingxiao; Cheng, Jinqian; Liang, Zibin; Tang, Yanqun; Qiu, Tianjie; Gao, Song; Zhong, Ruiqin; Zou, Ruqiang published an article in Small. The title of the article was 《Puffing Up Hollow Carbon Nanofibers with High-Energy Metal-Organic Frameworks for Capacitive-Dominated Potassium-Ion Storage》.Reference of 1H-1,2,3-Triazole The author mentioned the following in the article:

Nitrogen-doped carbon materials with abundant defects and strong potassium adsorption ability have been recognized as potential anodes for potassium ion batteries (PIBs). However, the limited content and uncontrolled type of nitrogen-doped sites hinder the further performance improvement of PIBs. Herein, this work proposes nitrogen phosphorous co-doped hollow carbon nanofibers (PNCNFs) derived from high-energy metal-organic frameworks (MOFs) with an ultra-high nitrogen content of 19.52 wt% and a high portion of more reactive pyridinic N sites. Furthermore, the highly open architecture exploded by released gases from high-energy MOFs provides sufficient edge sites to settle the N atoms and further form pyridinic N sites induced by phosphorous dopants. The resulting PNCNFs achieve excellent potassium ion storage performance with high reversible capacity (466.2 mAh g-1), superb rate capability (244.4 mAh g-1 at 8 A g-1), and excellent cycling performance (294.6 mAh g-1 after 3250 cycles). The d. functional theory calculation reveals that the N/P defects enhance the potassium adsorption ability and improve the conductivity The experimental process involved the reaction of 1H-1,2,3-Triazole(cas: 288-36-8Reference of 1H-1,2,3-Triazole)

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Reference of 1H-1,2,3-Triazole

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

The author of 《Development of human serum albumin selective fluorescent probe using thieno[3,2-b]pyridine-5(4H)-one fluorophore derivatives》 were Lee, Suji; Sung, Dan-Bi; Kang, Seungyoon; Parameswaran, Saravanan; Choi, Jun-Ho; Lee, Jong Seok; Han, Min Su. And the article was published in Sensors in 2019. Recommanded Product: 56602-33-6 The author mentioned the following in the article:

The level of human serum albumin (HSA) in biol. fluids is a key health indicator and its quant. determination has great clin. importance. In this study, we developed a selective and sensitive fluorescent HSA probe by fluorescence-based high-throughput screening of a set of fluorescent thieno[3,2-b]pyridine-5(4H)-one derivatives against major plasma proteins: HSA, bovine serum albumin (BSA), globulin, fibrinogen, and transferrin. The fluorophore chosen finally (4) showed noticeable fluorescence enhancement in the presence of HSA (160-fold increase), and it exhibited rapid response, high sensitivity (detection limit 8 nM), and the ability to clearly distinguish HSA from BSA in pH 9 buffer condition. Moreover, the probe could be applicable to detect trace amounts of HSA in an artificial urine sample; further, it might be applied to the determination of the HSA concentration in complex biol. samples for pre-clin. diagnosis. In the part of experimental materials, we found many familiar compounds, such as ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6Recommanded Product: 56602-33-6)

((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)(cas: 56602-33-6) is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It acts as a substitute for (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.Recommanded Product: 56602-33-6

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

《Energetic metal-organic frameworks derived highly nitrogen-doped porous carbon for superior potassium storage》 was written by Tong, Huigang; Wang, Changlai; Lu, Jian; Chen, Shi; Yang, Kang; Huang, Minxue; Yuan, Qing; Chen, Qianwang. Electric Literature of C2H3N3 And the article was included in Small in 2020. The article conveys some information:

The carbonaceous materials with low cost and high safety have been considered as promising anodes for potassium-ion batteries (PIBs). However, it is still a challenge to design a carbonaceous material with long cycle life and high rate performance due to the poor K+ reaction kinetics. Herein, this article reports a N-doped porous carbon framework (NPCF) with a high nitrogen content of 13.57 at% within high doping level of the pyrrolic N and pyridinic N, which exhibits a high reversible capacity of 327 mA h g-1 over 100 cycles at a c.d. of 100 mA g-1, excellent rate capability (144 and 105 mA h g-1 at 10 and 20 A g-1, resp.) and great cyclability of 258.9 mA h g-1 after 2000 cycles at 1 A g-1. Such a high rate performance and excellent cycling stability anode material is seldom reported in PIBs. D. functional theory (DFT) calculations reveal that the pyrrolic and pyridinic N-doping are helpful to enhance the K adsorption ability, thereby increasing the specific capacity. In addition to this study using 1H-1,2,3-Triazole, there are many other studies that have used 1H-1,2,3-Triazole(cas: 288-36-8Electric Literature of C2H3N3) was used in this study.

1H-1,2,3-Triazole(cas: 288-36-8) belongs to triazoles. Triazoles are an important group of nitrogen-containing five-membered heterocyclic scaffolds. Triazoles are core structures of several drugs and pharmaceutical agents. Triazole derivatives possess antimicrobial, antiparasitic, antidiabetic, analgesic, and anti-inflammatory properties Electric Literature of C2H3N3

Referemce:
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics