Month: November 2021

Name: 1H-1,2,4-Triazol-5-amine. Recently I am researching about HIRSHFELD SURFACE-ANALYSIS; X-RAY; BENZIMIDAZOLE; DERIVATIVES; OXIDATION; ISOMERISM; LIGAND; CO(II); ALPHA; ACID, Saw an article supported by the Fonds de la Recherche Scientifique-FNRSFonds de la Recherche Scientifique – FNRS [CDR 33694457]; bilateral WBI action with Morocco (COP 22 Program 2018-2022). Published in ELSEVIER SCIENCE INC in NEW YORK ,Authors: Chkirate, K; Fettach, S; El Hafi, M; Karrouchi, K; Elotmani, B; Mague, JT; Radi, S; Faouzi, ME; Adarsh, NN; Essassi, E; Garcia, Y. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Two Cu(II) coordination complexes, C1 and C2 of the formula [Cu(4)2(H2O)(2)], have been prepared by reaction between CuCl2 center dot 2H(2)O and 7-ethoxycarbonylmethyl-5-methyl-1,2,4[1,5-a]pyrimidine (L) in a 1:2 M:L molar ratio. The L molecule decomposes during the reaction process into 7-carboxy-5-methyl-[1,2,4]-triazolo[1,5-a]pyrimidine (4) through an intermediate, ethyl 2,2-dihydroxy-2-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl) acetate (5), which has been isolated and its crystal structure determined by X-ray diffraction. The X-ray analysis of the single crystals of [Cu(4)(2)(H2O)(2)] obtained from the slow evaporation of EtOH and MeOH, separately, revealed the formation of solvent induced polymorphs C1 and C2, respectively. The primary supramolecular synthon for C1 and C2 are six membered ring, and square shaped hydrogen bonded architecture, respectively. The self-assembly of such synthons resulted in a two dimensional hydrogen bonded sheet supported by O-H center dot center dot center dot O interactions. In addition, the antioxidant properties of the ligands and its complexes were evaluated in vitro using 1,1-diphenyl-2-picrylhydrazyl acid, 2,2′-azino-bis (3-ethylbenzothiazoline-6 sulfonic acid radical scavenging methods and ferric reducing antioxidant power.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Name: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Computed Properties of C2H4N4. In 2021.0 INT J BIOL MACROMOL published article about SOFTWOOD KRAFT LIGNIN; POLYPROPYLENE; POLYETHYLENE; TOUGHNESS; BLENDS in [Huang, Jinhao; Liu, Weifeng; Tu, Zhikai; Li, Jinxing; Lou, Hongming] South China Univ Technol, Guangdong Engn Res Ctr Green Fine Chem, Sch Chem & Chem Engn, Wushan Rd 381, Guangzhou 510640, Guangdong, Peoples R China; [Qiu, Xueqing] Guangdong Univ Technol, Guangzhou Higher Educ Mega Ctr, Sch Chem Engn & Light Ind, Waihuan Xi Rd 100, Guangzhou 510006, Peoples R China in 2021.0, Cited 31.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In this work, the coordination-based energy sacrificial bonds have been constructed in the interphase between lignin and polyolefin elastomer to prepare high performance lignin-based thermoplastic elastomers (TPEs). The strength and toughness of lignin-based TPEs can be adjusted by choosing different nitrogen heterocyclic compounds as reactive assistants and Fe3+ or Zr2+ as metal coordination centers. It was demonstrated that 3-Amino-1,2,4-triazole with three nitrogen atoms in the heterocydic ring and one nitrogen branch chain could form the most efficient coordination bond system and generate the best mechanical performance. The system with ferric iron as coordination center exhibited better enhancement effect than divalent zinc. By adjusting the nitrogen-containing reactive additives or metal salts as coordination centers, the mechanical performance of the lignin-based TPE can be regulated, which provides a method for making green bio-composites with good strength and toughness, and also promotes the high value utilization of lignin in polymer materials. (C) 2021 Elsevier B.V. All rights reserved.

Welcome to talk about 61-82-5, If you have any questions, you can contact Huang, JH; Liu, WF; Qiu, XQ; Tu, ZK; Li, JX; Lou, HM or send Email.. Computed Properties of C2H4N4

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

In 2019.0 NANO published article about EFFICIENT CARBOCATALYST; NANOPARTICLES; GRAPHENE; ACID; NANOSPHERES; PERFORMANCE; ELECTRODES; OXIDATION in [Zhou, Shenghai; Xu, Hongbo; Wei, Yanjun; Gao, Jing; Feng, Yue; Gao, Junfeng] Hebei Normal Univ Nationalities, Dept Chem & Chem Engn, Chengde 067000, Peoples R China; [Wang, Ning] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050024, Hebei, Peoples R China in 2019.0, Cited 43.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Safety of 1H-1,2,4-Triazol-5-amine

Heteroatom-doped ordered mesoporous carbons (OMCs) have currently been considered as promising electrode materials for electrochemical sensors due to the combined advantages of ordered mesoporous materials and heteroatom-doped carbon materials. Herein, a novel nitrogen and sulfur co-doped OMCs (N,S-OMC) has been prepared via a nanocasting strategy with an inexpensive methylene blue as single precursor. The obtained mesoporous carbon has platelet morphology, short mesoporous channel together with a large surface area (549 m(2)/g) as well as rich N- and S-containing functional groups (6.8 at.% N and 2.3 at.% S). Compared with the graphene (GR) and carbon nanotube (CNT) electrode material, the N,S-OMC exhibited a higher electrochemical activity towards the oxidation of herbicide amitrole, ascribable to N,S-OMC’s open mesoporous structures and abundant electroactive defect sites on the carbon skeleton. And, an amitrole electrochemical sensor with N,S-OMC modified electrode as working electrode was fabricated, exhibiting a good selectivity, stability, reproducibility and wide linear range of 3-750 mu M. Moreover, the N,S-OMC-based electrochemical sensor was proved feasible in river water sample analyses, showing a satisfied recovery ranging from 97.03% to 105.42%. The results not only demonstrate cheap methylene blue can be used as single precursor for the N,S-OMC preparation, but also confirm the N,S-OMC is promising in amitrole sensor fabrication.

Welcome to talk about 61-82-5, If you have any questions, you can contact Zhou, SH; Xu, HB; Wei, YJ; Gao, J; Feng, Y; Wang, N; Gao, JF or send Email.. Safety of 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

HPLC of Formula: C2H4N4. Recently I am researching about APIS-MELLIFERA; NEONICOTINOID INSECTICIDES; ENVIRONMENTAL RISKS; WARDECKER WATERERS; WATERING DEVICE; SURFACE WATERS; HYMENOPTERA; RESIDUES; WORKERS; APIDAE, Saw an article supported by the Prime-Vert; Volet 4 – Appui au developpement et au transfert de connaissances en agroenvironnement of the Ministere de l’Agriculture, des Pecheries et de l’Alimentation du Quebec (MAPAQ) [LAVA-1-13-1690]. Published in SPRINGER HEIDELBERG in HEIDELBERG ,Authors: McCune, F; Samson-Robert, O; Rondeau, S; Chagnon, M; Fournier, V. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

Water is essential for honey bees (Apis mellifera L.), but contaminated sources of water in agricultural environments represent a risk of exposure to potentially harmful contaminants. Providing clean water to honey bees could be an efficient and cost-effective measure for beekeepers to reduce bee mortality associated with pesticides and improve the health of their colonies. The main goal of this study was to design a waterer prototype to fulfill the water requirements of honey bees and to evaluate the potential of this waterer in improving colonies’ health in agricultural settings, through mitigating the possible impact of an exposure to pesticides from puddle water. We tested the preference of honey bees regarding water composition and waterer prototypes, among which honey bees showed a strong preference for salted water and a poultry-type waterer. Our waterer models were quickly adopted and intensively used through the season in both the context of honey production in field crops and pollination services in cranberry crops. However, in neither context did the use of waterers reduce worker mortality nor increase overall colony weight. Our waterers provided bees with water containing fewer pesticides and were associated with reduced risks of drowning compared to natural sources of water. Our study suggests that the use of waterers fulfills an important requirement for honey bees and represents an interesting and convenient precautionary measure for beekeepers.

HPLC of Formula: C2H4N4. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

Product Details of 61-82-5. Recently I am researching about DRUG; 5-ENE-4-THIAZOLIDINONES; INHIBITORS; DESIGN; AGENTS; ASSAY, Saw an article supported by the . Published in ACADEMIC PRESS INC ELSEVIER SCIENCE in SAN DIEGO ,Authors: Holota, S; Kryshchyshyn, A; Derkach, H; Trufin, Y; Demchuk, I; Gzella, A; Grellier, P; Lesyk, R. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

A series of novel 2-(5-aminomethylene-4-oxo-2-thioxothiazolidin-3-yl)-3-phenylpropionic acid ethyl esters has been synthesized. Target compounds were evaluated for their trypanocidal activity towards Trypanosoma brucei brucei and Trypanosoma brucei gambiense. Several hit-compounds (8, 10, 12) inhibited growth of the parasites at sub-micromolar concentrations (IC50 0.027-1.936 mu M) and showed significant selectivity indices (SI= 108-1396.2) being non-toxic towards the human primary fibroblasts. The screening of anticancer activity in vitro within NCI DTP protocol allowed to identify active 2-(5-{[5-(2,4-dichlorobenzyl)-thiazol-2-ylamino]methylene}- 4-oxo-2-thioxothiazolidin-3-yl)-3-phenylpropionic acid ethyl ester 14 that demonstrated inhibition against all 59 human tumor cell lines with the average GI(50) value of 2.57 mu M. It was established that the activity type (antitrypanosomal or anticancer) as well as its level depends on the character of enamine fragment in the C5 position of thiazolidinone core.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Synthesis of Some Benzimidazole-based Heterocycles and their Application as Copper Corrosion Inhibitors WOS:000458310800002 published article about SODIUM-CHLORIDE SOLUTIONS; ACIDIC PICKLING SOLUTIONS; MILD-STEEL; ALUMINUM CORROSION; ANODIC-DISSOLUTION; BENZOTRIAZOLE; SERIES; DERIVATIVES; ADDITIONS in [Eldebss, Taha M. A.; Farag, Ahmad M.] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt; [Shamy, Adel Y. M.] Egyptian Energy & Elect Minist, Cent Chem Labs, Cairo, Egypt in 2019.0, Cited 62.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Product Details of 61-82-5

A series of new substituted benzimidazoles embedded with a variety of function groups has been synthesized from N-methyl-2-bromoacetylbenzimidazole. The synthesized compounds were fully characterized, and their structures were elucidated based on elemental analysis, spectral data, and alternative synthetic pathways, whenever possible. Some of benzimidazole derivatives were tested as corrosion inhibitors.

Product Details of 61-82-5. Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Development of a Multiresidue Method for Endocrine-Disrupting Pesticides by Solid Phase Extraction and Determination by UHPLC-MS/MS from Drinking Water Samples published in 2020.0. Product Details of 61-82-5, Reprint Addresses Liu, SY (corresponding author), Hangzhou Ctr Dis Control & Prevent, Lab Chem & Phys, Hangzhou, Peoples R China.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

A rapid and efficient method based on solid phase extraction and liquid chromatography-tandem mass spectrometry was validated, allowing the determination of the endocrine-disrupting herbicides (acetochlor, alachlor, amitrole and atrazine), fungicides (carbendazim, triadimefon, penconazole and propiconazole), and insecticides (carbaryl and carbofuran) in drinking water. Low method detection limits (0.01-0.64 ng/L) and method quantification limits (0.03-2.13 ng/L) were obtained with satisfactory recoveries and precision for the endocrine-disrupting pesticides. The method was applied for real drinking water samples collected in the area of the city of Hangzhou (Zhejiang, China); the results showed that carbendazim, atrazine and acetochlor were detected in the drinking water samples and acetochlor was the most detected analyte.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Product Details of 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

An article Direct measurements of the reactivity of singlet oxygen to some persistent herbicides in aqueous solutions WOS:000527924400062 published article about DISSOLVED ORGANIC-MATTER; MOLECULAR-OXYGEN; PHOTOLYSIS; DEGRADATION; PESTICIDES; MECHANISM; ATRAZINE; STATE in [Pozdnyakov, Ivan P.] Novosibirsk State Univ, Novosibirsk 630090, Russia; [Pozdnyakov, Ivan P.] VV Voevodsky Inst Chem Kinet & Combust, Novosibirsk 630090, Russia; [Parkhats, Marina, V] Natl Acad Sci Belarus, BI Stepanov Inst Phys, Minsk 220072, BELARUS in 2020.0, Cited 15.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Reactivity of the singlet oxygen (SO), which is assumed to be one of the important oxidizers in natural waters, towards to a set of persistent herbicides, was measured for the first time using time resolved luminescence technique. It was observed that rate constants of SO reactions with the majority of studied herbicides are less than 10(6) M(-1)s(-1) allowing to conclude about negligible participation of SO in oxidation of the compounds in natural waters. (C) 2020 Elsevier Ltd. All rights reserved.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 1H-1,2,4-Triazol-5-amine

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

SDS of cas: 61-82-5. In 2020.0 CHEMISTRYSELECT published article about TRANSITION-METAL COMPOUNDS; DENSITY-FUNCTIONAL THEORY; MOLECULAR-STRUCTURES; DOCKING; MOLYBDENUM; INDOLES; MANNICH; BONDS in [El Sayed, Mardia T.] Natl Res Ctr, Chem Ind Res Div, Appl Organ Chem Dept, Dokki 12311, Egypt; [Sarhan, Alaadin E.] Natl Res Ctr, Pharmaceut Div, Therapeut Chem Dept, Dokki 12311, Egypt; [Ahmed, Entsar] Al Azhar Univ, Chem Dept, Fac Sci, Girls Branch, Cairo, Egypt; [Khattab, Reham R.] Natl Res Ctr, Chem Ind Res Div, Photochem Dept, Dokki 12311, Egypt; [Elnaggar, Mohamed] Univ Sharjah, Fac Sci, Chem Dept, Sharjah 27272, U Arab Emirates; [El-Messery, Shahenda M.] Mansoura Univ, Fac Pharm, Dept Organ Pharmaceut Chem, POB 35516, Mansoura, Egypt; [Shaldam, Moataz A.] Kafrelsheikh Univ, Fac Pharm, Dept Pharmaceut Chem, Kafr Al Sheikh 33516, Egypt; [Hassan, Ghada S.] Mansoura Univ, Fac Pharm, Dept Med Chem, Mansoura 35516, Egypt in 2020.0, Cited 39.0. The Name is 1H-1,2,4-Triazol-5-amine. Through research, I have a further understanding and discovery of 61-82-5.

In the present investigation, some novel nitro Mannich bases derived from Michael type addition of activated nitro olefin, beta-nitrostyrene with various amines either primary or secondary including some amino sugars were designed and synthesized. The produced Mannich bases have been full characterized through different spectroscopic techniques. Antimicrobial evaluation has been performed against the Gram positive S. aureus and methicillin-resistant S. aurues (MRSA) infections. 5 of the synthesized compounds represent the best candidates in the biological screening, they have exhibited good activity with MIC values range from 100 to 250 mu g/ml. The active agents have been tested for pyruvate kinase inhibition activity with % of inhibition range from 30 to 79 % with IC50 in a nano molar range. They also exhibited significant Pyruvate kinase inhibition in nanomolar range with IC50 of 1066, 662, 1887, 418 and 1128 ng/ml, respectively (versus 196 ng/ml for AZD7545). Molecular docking calculations for active agents were performed. A complete conformational analysis molecular modeling utilizing Gaussian 09 program (HF/DFT) was used to verify the mode of bonding through the optimized geometries as well as essential quantum parameters were calculated using frontier energies (EHOMO & ELUMO) for the active candidates indicating the overall stability of the structure.

Welcome to talk about 61-82-5, If you have any questions, you can contact El Sayed, MT; Sarhan, AE; Ahmed, E; Khattab, RR; Elnaggar, M; El-Messery, SM; Shaldam, MA; Hassan, GS or send Email.. SDS of cas: 61-82-5

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics

I found the field of Pharmacology & Pharmacy very interesting. Saw the article Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction published in 2019.0. Category: Triazoles, Reprint Addresses Fesik, SW (corresponding author), Vanderbilt Univ, Dept Biochem, Sch Med, Nashville, TN 37232 USA.; Fesik, SW (corresponding author), Vanderbilt Univ, Dept Pharmacol, Sch Med, Nashville, TN 37232 USA.; Fesik, SW (corresponding author), Vanderbilt Univ, Dept Chem, Nashville, TN 37232 USA.. The CAS is 61-82-5. Through research, I have a further understanding and discovery of 1H-1,2,4-Triazol-5-amine

The treatment of tumors driven by overexpression or amplification of MYC oncogenes remains a significant challenge in drug discovery. Here, we present a new strategy toward the inhibition of MYC via the disruption of the protein-protein interaction between MYC and its chromatin cofactor WD Repeat-Containing Protein 5. Blocking the association of these proteins is hypothesized to disrupt the localization of MYC to chromatin, thus disrupting the ability of MYC to sustain tumorigenesis. Utilizing a high-throughput screening campaign and subsequent structure-guided design, we identify small-molecule inhibitors of this interaction with potent in vitro binding affinity and report structurally related negative controls that can be used to study the effect of this disruption. Our work suggests that disruption of this protein-protein interaction may provide a path toward an effective approach for the treatment of multiple tumors and anticipate that the molecules disclosed can be used as starting points for future efforts toward compounds with improved drug-like properties.

Bye, fridends, I hope you can learn more about C2H4N4, If you have any questions, you can browse other blog as well. See you lster.. Category: Triazoles

Reference:
Article; Safari, Niloufar; Shirini, Farhad; Tajik, Hassan; Journal of Molecular Structure; vol. 1201; (2020);,
1,2,3-Triazole – Wikipedia,
Triazoles – an overview | ScienceDirect Topics